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Metabolic syndrome on top of chronic hepatitis B: the more, the worse?
  1. Li-Chun Chang1,
  2. Chen-Shuan Chung1,
  3. Chun-Jen Liu1,2,3,
  4. Jia-Horng Kao1,2,3,4
  1. 1Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
  2. 2Graduate Institute of Clinical Medicine, National Taiwan University Hospital, Taipei, Taiwan
  3. 3Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan
  4. 4Department of Medical Research National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan
  1. Correspondence to Professor Jia-Horng Kao, Hepatitis Research Center, National Taiwan University Hospital, 1 Chang-Te Street, Taipei 10002, Taiwan; kaojh{at}ntu.edu.tw

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We read with interest the article entitled ‘Metabolic syndrome increases the risk of liver cirrhosis in chronic hepatitis B’ by Wong et al in the January 2009 of Gut.1 Chronic hepatitis B virus (HBV) infection remains a global health problem, affecting more than 350 million people worldwide. It is estimated that approximately one million chronic hepatitis B (CHB) patients die of liver-related diseases per annum. Through the launch of an effective hepatitis B vaccination programme for more than two decades, a dramatic decline of HBV infection rate as well as hepatocellular carcinoma (HCC) incidence rate has been observed in children of many HBV endemic countries.2 Nevertheless, CHB is still a health threat to adult HBV carriers. Therefore, it is important for …

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