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Hyponatraemia during terlipressin therapy
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We have read with interest the study by Lo et al1 in a recent issue of Gut. Apart from the findings that short-term therapy with terlipressin in combination with ligation seems to improve outcome in bleeding oesophageal varices (BOVs) compared to longer treatment with terlipressin, a shorter treatment period with terlipressin most likely reduces the risk of severe side effects. Recently, a study observed that during a 5-day terlipressin treatment with 1 mg/4 h, the serum sodium decreased from 138±5 to 130±9 and in …
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