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Hyponatraemia during terlipressin therapy
  1. Aleksander Krag1,2,
  2. Lise Hobolth1,2,
  3. Søren Møller2,
  4. Flemming Bendtsen1
  1. 1Department of Gastroenterology, Hvidovre University Hospital, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
  2. 2Department of Clinical Physiology, Hvidovre University Hospital, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
  1. Correspondence to Dr Aleksander Krag, Department of Medical Gastroenterology 439, Hvidovre Hospital, Hvidovre DK-2650, Denmark; aleksanderkrag{at}hotmail.com

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We have read with interest the study by Lo et al1 in a recent issue of Gut. Apart from the findings that short-term therapy with terlipressin in combination with ligation seems to improve outcome in bleeding oesophageal varices (BOVs) compared to longer treatment with terlipressin, a shorter treatment period with terlipressin most likely reduces the risk of severe side effects. Recently, a study observed that during a 5-day terlipressin treatment with 1 mg/4 h, the serum sodium decreased from 138±5 to 130±9 and in …

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