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We believe that the guidelines for the management of anticoagulant and antiplatelet treatment in patients undergoing endoscopic procedures, recently published in Gut, are an important tool for the correct management of such patients and are well balanced.1 However, we wish to make some comments about antiplatelet treatment. In the Introduction, the authors state that aspirin treatment can be continued for all endoscopic procedures (without reporting any reference), suggesting that this is an obvious and strongly evidence-based statement. In our opinion, although we broadly agree with this statement, evidence about it is weak. In fact, the “strongest” evidence about the low risk of bleeding after endoscopic biopsy or polipectomy in patients taking aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) comes from a prospective …
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