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  1. Grace Lai-Hung Wong,
  2. Vincent Wai-Sun Wong,
  3. Henry Lik-Yuen Chan
  1. Institute of Digestive Disease and Department of Medicine and Therapeutics, The Chinese University of Hong Kong; Hong Kong SAR, China
  1. Correspondence to Dr Henry LY Chan, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, 9/F Prince of Wales Hospital, 30–32 Ngan Shing Street, Shatin, Hong Kong, China; hlychan{at}cuhk.edu.hk

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We appreciate the interest and comments by Drs Jeng and Chu on our recent publication.1 We would like to acknowledge the results from the Taiwanese longitudinal study concerning the effect of fatty liver, obesity and type 2 diabetes on the risk of liver cirrhosis and hepatocellular carcinoma in a large cohort of patients with or without chronic hepatitis B (CHB) or chronic hepatitis C. This evidence echoed the conclusion of the present study that metabolic risk factors increased the risk of liver cirrhosis in CHB.

We re-examined our data concerning the …

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