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Surveillance in individuals at high risk of pancreatic cancer: too early to tell?
  1. Femme Harinck1,
  2. Marcia Irene Canto2,∗,§,
  3. Richard Schulick2,§,±,
  4. Michael Goggins2,∗,¶,§,
  5. Jan-Werner Poley1,
  6. Paul Fockens3,
  7. Irma Kluijt4,
  8. Marco Bruno1
  1. 1Department of Gastroenterology and Hepatology, Erasmus Medical Center, University Medical Center Rotterdam, the Netherlands
  2. 2Departments of ∗Medicine (Gastroenterology), ¶Pathology, §Oncology and, ±Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
  3. 3Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, the Netherlands
  4. 4Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, the Netherlands
  1. Correspondence to M J Bruno, Department of Gastroenterology and Hepatology, Erasmus Medical Center, University Medical Center Rotterdam, 's Gravendijkwal 230, Rotterdam 3015 CE, the Netherlands; m.bruno{at}erasmusmc.nl

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We have read with great interest the publication by Langer et al.1 Pancreatic cancer surveillance of high-risk individuals may have the potential to alter the dismal prognosis of this deadly disease. Although promising, its application is a learning experience and results of pancreatic cancer surveillance studies are eagerly awaited. Although we greatly value the efforts of Langer et al we have some comments and questions.

The title of their paper suggests a prospective cohort study with a median follow-up observation period of 5 years. …

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