Gut 60:1023-1024 doi:10.1136/gut.2010.232892
  • PostScript
  • Letter

Immediate effect on fertility of a gluten-free diet in women with untreated coeliac disease

  1. Margherita Bonamico
  1. Department of Pediatrics, “Sapienza” University of Rome, Rome, Italy
  1. Correspondence to Professor Margherita Bonamico, Department of Paediatrics “Sapienza” University of Rome. Viale Regina Elena 324, Rome 00161, Italy; margherita.bonamico{at}

In a recent paper in Gut, describing a Swedish population-based cohort, Zugna et al found that women with coeliac disease had normal fertility, but their fertility had decreased in the 2 years preceding the diagnosis of coeliac disease.1

This study provides important answers to fertility problems in patients with coeliac disease by analysing a nationwide database. The results, however, must be interpreted with caution. This paper may be considered confusing because the role of coeliac disease as one of the causes of infertility has been underestimated taking into account population studies in general. Infertility, spontaneous abortion and delayed puberty represent subclinical coeliac disease presentations …

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