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Letter
The Authors' reply
  1. Grazia Grazzini1,
  2. Marco Zappa2,
  3. Stephen P Halloran3
  1. 1Screening Department, Cancer Prevention and Research Institute (ISPO), Florence, Italy
  2. 2Clinical and Descriptive Epidemiology Department, Cancer Prevention and Research Institute (ISPO), Florence, Italy
  3. 3Bowel Cancer Screening Southern Programme Hub, Postgraduate Medical School, University of Surrey, Guildford, Surrey, England
  1. Correspondence to Grazia Grazzini, Department of Screening, Cancer Prevention and Research Institute (ISPO), Viale A. Volta 171 50131 Firenze, Italy; g.grazzini{at}ispo.toscana.it

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The Authors' reply The new data presented in Dr Zorzi's letter1 2 are a valuable contribution to the evolving evidence that colorectal cancer screening programmes that use an immunochemical faecal occult blood test (iFOBT) should expect a difference in clinical effectiveness between periods of …

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