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Letter
The relevance of symptom association analysis in GORD patients undergoing anti-reflux surgery
  1. Edoardo Savarino,
  2. Patrizia Zentilin,
  3. Simona Inferrera,
  4. Vincenzo Savarino
  1. Gastroenterology Unit, Department of Internal Medicine, University of Genoa, Genoa, Italy
  1. Correspondence to Edoardo Savarino, Di.M.I. Gastroenterology Unit, Department of Internal Medicine, University of Genoa, Genoa, Italy edoardo.savarino{at}unige.it

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We read with great interest the article by Broeders et al1 on the effects of anti-reflux surgery on weakly acidic reflux and belching. The authors evaluated 31 gastro-oesophageal reflux disease (GORD) patients, refractory to proton pump inhibitors, by means of upper gastrointestinal endoscopy, validated symptoms questionnaires, stationary oesophageal manometry and 24-hour impedance–pH monitoring off antisecretory therapy before and 6 months after laparoscopic Nissen fundoplication (LNF). They observed that LNF reduced oesophageal acid exposure time (AET) and proximal migration of reflux events and similarly controlled …

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