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  1. Aida Habtezion1,
  2. M Bishr Omary2
  1. 1Stanford University School of Medicine, Department of Medicine, Division of Gastroenterology and Hepatology, Stanford, California, USA
  2. 2University of Michigan Medical School, Department of Molecular and Integrative Physiology, Ann Arbor, Michigan, USA
  1. Correspondence to Dr Aida Habtezion, Stanford University School of Medicine, Department of Medicine, Division of Gastroenterology and Hepatology, 300 Pasteur Drive, Stanford, CA 94305-5187, USA; aidah{at}stanford.edu

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We thank Dr Braganza1 for the stimulating comments regarding our study.2 Haem-oxygenase-1 (HO-1) is a ubiquitous enzyme and plays an important role in many cell types. We previously demonstrated a protective role for HO-1+ monocytes/macrophages in acute pancreatitis using adoptive peritoneal cell transfers from haemin-treated mice into mice undergoing acute pancreatitis.3 We have not assessed the role or contribution of mast cells in our studies, …

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