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A patient with biliary colic and intestinal obstruction
  1. Bas W van der Spek1,
  2. Miguel A Cuesta2,
  3. Maarten A Jacobs1
  1. 1Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands
  2. 2Department of Surgery, VU University Medical Center, Amsterdam, The Netherlands
  1. Correspondence to Dr Bas W van der Spek, Department of Gastroenterology and Hepatology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands; b.vanderspek{at}vumc.nl

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Clinical presentation

A 38-year-old Caucasian male patient was referred to our emergency department with typical biliary colic. Medical and family history were unremarkable. Physical examination revealed a non-feverish mildly ill patient, with normal bowel sounds. In addition a remarkably ‘freckled’ skin was found, especially on periorbital and perioral skin and buccal mucosa (figure 1). Apart from abnormal liver enzymes (bilirubin 1.35 mg/dl, gamma-glutamyltransferase 1049 IU/l and alanine aminotransferase 286 IU/l) laboratory tests were normal. Abdominal ultrasonography showed dilated intra- and extrahepatic bile ducts and cholecystolithiasis but no signs of choledocholithiasis. An endoscopic retrograde cholangiopancreatography was performed because of presumed choledocholithiasis, but common bile duct cannulation was unsuccessful because of a large polypoid mass at its insertion (figure 2). During endoscopy multiple smaller polyps were seen in duodenum and stomach. Following endoscopic retrograde cholangiopancreatography …

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