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Parry and colleagues1 described the long-term follow-up in a large cohort of mismatch repair (MMR) gene mutation carriers and estimated that among the 332 subjects who had segmental resections, the risk of metachronous colorectal cancer (CRC) was 62% at 30 years after segmental colectomy. In this setting, the appropriate estimate of the probability of failure (ie, metachronous CRC) is cumulative incidence, but as illustrated by Gooley et al,2 the complement of a Kaplan–Meier estimate (1-KM), as used in this paper, is often inappropriately used. In using 1-KM, the failures from a competing event (eg, …
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