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Prothrombin index slope is an early prognostic marker in patients with severe acute liver diseases
  1. Bertrand Nalpas1,2,
  2. Claire Francoz3,
  3. Philippe Ichaï4,
  4. Laure Jamot5,
  5. Jamila Faivre6,7,
  6. Sara Lemoinne4,
  7. Didier Samuel4,6,
  8. François Durand3,8,
  9. Jacques Bernuau3,
  10. Christian Bréchot5,6,
  11. Paul Amouyal5,
  12. Gilles Amouyal5
  1. 1U1016, Inserm, Paris, France
  2. 2Unité d'Hépatologie, Hôpital Cochin, Paris, France
  3. 3Pôle des maladies de l'appareil digestif, Service d'Hépatologie, Unité de réanimation hépato-digestive, Hôpital Beaujon, Clichy, France
  4. 4Centre de Soins Intensifs Hépatique, Centre Hépato-Biliaire, Hôpital Paul Brousse, Villejuif, France
  5. 5Alfact Innovation, Paris, France
  6. 6U785, Inserm, Villejuif, France
  7. 7Faculté de Medecine, Université Paris sud, Villejuif, France
  8. 8U773, Inserm, Clichy, France
  1. Correspondence to Dr Gilles Amouyal, Alfact Innovation, 320 rue Saint Honoré, Paris 75001, France; gamouyal{at}orange.fr

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