Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi)

Qiuwei Pan; Vedashree Ramakrishnaiah; Scot Henry; Suomi Fouraschen; Petra E de Ruiter; Jaap Kwekkeboom; Hugo W Tilanus; Harry L A Janssen; Luc J W van der Laan

doi:10.1136/gutjnl-2011-300449

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Hepatology

Original article

Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi)

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	Abstract	Full	Pdf
Dec 2011	122	49	57
Jan 2012	225	165	125
Feb 2012	104	52	37
Mar 2012	129	64	36
Apr 2012	119	41	61
May 2012	40	19	16
Jun 2012	67	23	17
Jul 2012	37	25	8
Aug 2012	774	42	77
Sep 2012	607	22	36
Oct 2012	311	14	27
Nov 2012	211	27	35
Dec 2012	132	17	19
Jan 2013	129	23	31
Feb 2013	120	15	16
Mar 2013	74	17	14
Apr 2013	84	26	19
May 2013	62	18	20
Jun 2013	36	12	15
Jul 2013	57	12	14
Aug 2013	60	10	11
Sep 2013	58	12	9
Oct 2013	61	11	17
Nov 2013	49	16	17
Dec 2013	46	11	16
Jan 2014	41	9	7
Feb 2014	27	13	37
Mar 2014	37	8	26
Apr 2014	30	6	24
May 2014	41	16	21
Jun 2014	33	14	22
Jul 2014	63	12	33
Aug 2014	37	6	6
Sep 2014	35	11	33
Oct 2014	50	11	28
Nov 2014	30	13	28
Dec 2014	31	8	26
Jan 2015	35	10	10
Feb 2015	23	10	6
Mar 2015	31	12	11
Apr 2015	28	6	5
May 2015	33	10	11
Jun 2015	32	6	12
Jul 2015	13	4	2
Aug 2015	38	12	11
Sep 2015	35	4	8
Oct 2015	15	5	7
Nov 2015	37	19	11
Dec 2015	31	10	8
Jan 2016	27	9	7
Feb 2016	18	1	0
Mar 2016	27	5	8
Apr 2016	21	8	8
May 2016	26	8	7
Jun 2016	17	2	7
Jul 2016	34	5	4
Aug 2016	29	9	8
Sep 2016	61	9	15
Oct 2016	29	9	5
Nov 2016	30	5	9
Dec 2016	26	5	7
Jan 2017	36	4	2
Feb 2017	25	4	5
Mar 2017	41	7	5
Apr 2017	24	5	2
May 2017	32	11	7
Jun 2017	36	8	10
Jul 2017	57	4	2
Aug 2017	48	3	3
Sep 2017	51	3	2
Oct 2017	92	14	5
Nov 2017	89	9	5
Dec 2017	65	5	1
Jan 2018	152	4	3
Feb 2018	45	4	0
Mar 2018	70	3	3
Apr 2018	127	7	1
May 2018	69	7	1
Jun 2018	74	5	2
Jul 2018	51	9	3
Aug 2018	69	7	4
Sep 2018	53	7	6
Oct 2018	62	3	2
Nov 2018	60	7	3
Dec 2018	49	4	7
Jan 2019	129	2	1
Feb 2019	46	8	4
Mar 2019	43	6	4
Apr 2019	72	3	2
May 2019	43	7	5
Jun 2019	63	7	2
Jul 2019	27	4	2
Aug 2019	45	3	0
Sep 2019	35	5	1
Oct 2019	53	4	3
Nov 2019	41	2	0
Dec 2019	43	6	3
Jan 2020	60	8	4
Feb 2020	53	3	7
Mar 2020	45	3	2
Apr 2020	78	5	3
May 2020	64	9	3
Jun 2020	30	2	1
Jul 2020	37	2	1
Aug 2020	24	2	4
Sep 2020	58	6	7
Oct 2020	39	6	3
Nov 2020	81	9	4
Dec 2020	27	3	4
Jan 2021	65	6	3
Feb 2021	55	4	5
Mar 2021	93	5	2
Apr 2021	55	5	2
May 2021	13	3	1
Jun 2021	9	8	2
Jul 2021	4	4	2
Aug 2021	10	6	2
Sep 2021	1	0	2
Oct 2021	116	4	7
Nov 2021	44	2	1
Dec 2021	86	12	0
Jan 2022	58	15	4
Feb 2022	51	3	0
Mar 2022	60	7	2
Apr 2022	50	4	1
May 2022	85	8	0
Jun 2022	109	3	1
Jul 2022	57	5	5
Aug 2022	100	3	1
Sep 2022	81	8	3
Oct 2022	75	6	3
Nov 2022	80	9	3
Dec 2022	102	10	3
Jan 2023	108	3	0
Feb 2023	62	2	0
Mar 2023	67	7	2
Apr 2023	60	4	1
May 2023	71	6	1
Jun 2023	34	2	0
Jul 2023	56	3	0
Aug 2023	55	3	0
Sep 2023	64	8	0
Oct 2023	231	3	0
Nov 2023	523	1	0
Dec 2023	110	2	0
Jan 2024	50	1	1
Feb 2024	78	4	8
Mar 2024	68	2	2
Total	10674	1503	1452

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