Direction of the brain–gut pathway in functional gastrointestinal disorders
- 1Leeds Gastroenterology Institute, St James's University Hospital, Leeds, UK
- 2Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK
- Correspondence to Dr Alexander C Ford, Leeds Gastroenterology Institute, Room 125, 4th Floor, Bexley Wing, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK; alexf12399{at}yahoo.com
- Accepted 3 February 2012
- Published Online First 2 March 2012
- Functional dyspepsia
- Irritable bowel syndrome
- anxiety
- depression
- absorption
- functional bowel disorder
- helicobacter pylori—treatment
- helicobacter pylori—epidemiology
- meta-analysis
- cost-effectiveness
We read the paper by Koloski and colleagues with interest.1 The authors are to be congratulated for conducting a study in >1000 individuals from the general population over such a long period of time. Their finding that the brain–gut axis appears to be bidirectional in functional gastrointestinal (GI) disorders is both important and novel.
In another longitudinal survey with a similar design, but with 10 years of follow-up, poor quality of …
