Article Text


Oesophageal II
PWE-038 Influence of postoperative morbidity on longterm cancer survival after oesophagogastric surgery
  1. A Eltweri,
  2. S Satheesan,
  3. S Ubhi,
  4. D Bowrey
  1. Department of Surgery, University Hospitals of Leicester NHS Trust, Leicester, UK


Introduction Previous studies have shown that postoperative adverse events after colorectal resection predict a poor prognosis with early cancer relapse. The aim of this study was to report the outcome of patients undergoing oesophagogastric resection to assess the influence of in-hospital factors on longterm cancer survival.

Methods Retrospective review of patients undergoing oesophagogastric resection for carcinoma during the years 2006–2010 at our institution. Minimum follow-up of 12 months was required.

Results The study population was 164 patients (110 male) of median age 64 years (range 32–84). 84 underwent oesophagectomy, 80 gastrectomy. 99 received neoadjuvant chemotherapy. The 90-day, 1-year and 3-year survivals were 92%, 84% and 49% respectively. 69 patients (42%) developed postoperative complications (commonest: pneumonia 19%, anastomotic leak 7%, wound infection 6%). None of tumour site (oesophagus vs stomach, p=0.73), length of ITU stay (<3 days vs >3 days, p=0.50) or development of postoperative complications (p=0.70) influenced longterm prognosis. The only two factors that influenced longterm outcome were UICC stage (p<0.001) and circumferential resection margin (positive vs negative, p<0.001).

Conclusion Patients experiencing postoperative morbidity can expect the same longterm oncologic outcome as those not suffering these early setbacks.

Competing interests None declared.

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