A rare cause of dysphagia
- 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands
- 2Department of Radiology, Maastricht University Medical Center, Maastricht, The Netherlands
- 3Department of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands
- Correspondence to Dr José M Conchillo, Division of Gastroenterology and Hepatology, Maastricht University Medical Center, PO Box 5800, 6202 AZ Maastricht, The Netherlands; j.conchillo{at}mumc.nl
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Contributors JMC: identified the case, conception and drafting of the manuscript; MdH: principal radiologist, review of manuscript; GWHS: principal surgeon, review of manuscript; AAMM: gastroenterologist, critical revision of manuscript.
- Accepted 6 April 2012
- Published Online First 3 June 2012
- Gastrointestinal motility
- gastroesophageal reflux disease
- intestinal motility
- probiotics
- oesophageal motility
- oesophageal physiology
- epithelial barrier
- colorectal motility
- functional dyspepsia
- colorectal function
- gastrointestinal hormones
- small bowel motility
- visceral hypersensitivity
- functional bowel disorder
- irritable bowel syndrome
- microscopic colitis
Clinical presentation
A 54-year-old woman, with a history of partial strumectomy due to hyperthyroidism, was referred for evaluation of chronic dysphagia for solids for more than 10 years. In the last few months, she was only fed on a liquid diet and lost approximately 6 kg in weight. Neither reflux symptoms nor thoracic pain were present. Physical examination and screening blood tests were unremarkable. Upper endoscopy (supplementary video, figure 1), oesophageal high-resolution manometry (figure 2 …








