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Gut 62:182-184 doi:10.1136/gutjnl-2012-302656
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Quantitative hepatitis B core antibody level may help predict treatment response in chronic hepatitis B patients

  1. Ning-Shao Xia1
  1. 1National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen, China
  2. 2Graduate Institute of Clinical Medicine and Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
  3. 3Youan Hospital, Capital Medical University, Beijing, China
  4. 4Zhongshan Hospital and College of Medicine, Xiamen University, Xiamen, China
  5. 5China Medical University Hospital, China Medical University, Taichung, Taiwan
  1. Correspondence to Professor Jun Zhang, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, Xiamen University, Siming South Road No. 422, Xiamen 361005. China; zhangj{at}xmu.edu.cn

  1. Contributors JZ, NSX and PJC are co-corresponders for this paper. Study concept and design: QY, JZ, P-JC and N-SX. Acquisition of data: QY, L-WS, C-JL, C-HH, S-XG and Y-BW. Analysis and interpretation of data: QY, L-WS, P-JC. Drafting of the manuscript: QY and P-JC. Critical revision of the manuscript for important intellectual content: P-JC, JZ, J-HK, D-SC and N-SX. Statistical analysis: QY and L-WS. Technical, or material support: C-JC, ZL, P-GL, YY and C-YP. Obtained funding: S-XG, JZ and N-SX. Study supervision: JZ and N-SX. Approval of the final version of the manuscript: P-JC, JZ and N-SX.

  • Accepted 15 May 2012
  • Published Online First 14 June 2012

We read with interest the recent article by Dandri emphasising the use of novel quantitative biomarkers as tools for predicting treatment response and disease progression in chronic hepatitis B infection (CHB).1 The authors carried out a comprehensive review of the clinical implications of quantitative measurement of viral biomarkers both in blood and in liver, such as: serum HBsAg, serum HBeAg and intrahepatic cccDNA, based on current knowledge.1 In addition to these, …

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