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Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk

Authors

  • Sebastian Beer Department of Molecular and Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Jiayi Zhou Department of Molecular and Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • András Szabó Department of Molecular and Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Steven Keiles Ambry Genetics Corp., Aliso Viejo, California, USA PubMed articlesGoogle scholar articles
  • Giriraj Ratan Chandak Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Hyderabad, India PubMed articlesGoogle scholar articles
  • Heiko Witt Else Kröner-Fresenius-Zentrum für Ernährungsmedizin (EKFZ) & Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL), Technische Universität München (TUM), Freising, Germany Department of Pediatrics, Klinikum rechts der Isar (MRI), Technische Universität München (TUM), Munich, Germany PubMed articlesGoogle scholar articles
  • Miklós Sahin-Tóth Department of Molecular and Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Miklós Sahin-Tóth, Department of Molecular and Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University, 72 East Concord Street, Evans-433, Boston, MA 02118, USA; miklos{at}bu.edu
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Citation

Beer S, Zhou J, Szabó A, et al
Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk

Publication history

  • Received July 17, 2012
  • Accepted August 2, 2012
  • First published September 1, 2012.
Online issue publication 
October 26, 2017

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