Table of contents

Original articles

Oesophagus

• Original article: Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus (13 April, 2012)

  Willemijn A van Dop, Sanne L Rosekrans, Anja Uhmann, Viljar Jaks, G Johan A Offerhaus, Marius A van den Bergh Weerman, Maria Kasper, Jarom Heijmans, James C H Hardwick, Hein W Verspaget, Daan W Hommes, Rune Toftgård, Heidi Hahn, Gijs R van den Brink

Helicobacter pylori

• Original article:

  Protein kinase C isozymes regulate matrix metalloproteinase-1 expression and cell invasion in Helicobacter pylori infection

  (22 March, 2012)

  Olga Sokolova, Michael Vieth, Michael Naumann

Inflammatory bowel disease

• Original article: Work disability in inflammatory bowel disease patients 10 years after disease onset: results from the IBSEN Study (20 June, 2012)

  Marte Lie Høivik, Bjørn Moum, Inger Camilla Solberg, Magne Henriksen, Milada Cvancarova, Tomm Bernklev, IBSEN Group
• Original article: mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease (25 April, 2012) Free

  Stefanie Derer, Andreas Till, Robert Haesler, Christian Sina, Nils Grabe, Sascha Jung, Susanna Nikolaus, Tanja Kuehbacher, Joachim Groetzinger, Stefan Rose-John, Philip C Rosenstiel, Stefan Schreiber
• Original article: Preoperative biological therapy and short-term outcomes of abdominal surgery in patients with inflammatory bowel disease (22 May, 2012)

  Matti Waterman, Wei Xu, Amreen Dinani, A Hillary Steinhart, Kenneth Croitoru, Geoffrey C Nguyen, Robin S McLeod, Gordon R Greenberg, Zane Cohen, Mark S Silverberg

Endoscopy

• Original article: In vivo targeting of colonic dysplasia on fluorescence endoscopy with near-infrared octapeptide (17 March, 2012)

  Zhongyao Liu, Sharon J Miller, Bishnu P Joshi, Thomas D Wang

Colon

• Original article: Serrated polyposis: rapid and relentless development of colorectal neoplasia (5 April, 2012)

  Daniel L Edelstein, Jennifer E Axilbund, Linda M Hylind, Katharine Romans, Constance A Griffin, Marcia Cruz-Correa, Francis M Giardiello
• Original article: Random comparison of repeated faecal immunochemical testing at different intervals for population-based colorectal cancer screening (2 March, 2012)

  Aafke H C van Roon, S Luuk Goede, Marjolein van Ballegooijen, Anneke J van Vuuren, Caspar W N Looman, Katharina Biermann, Jacqueline C I Y Reijerink, Hans 't Mannetje, Alexandra C M van der Togt, J Dik F Habbema, Monique E van Leerdam, Ernst J Kuipers
• Original article:

  Heterocyclic amine intake, smoking, cytochrome P450 1A2 and N-acetylation phenotypes, and risk of colorectal adenoma in a multiethnic population

  (24 May, 2012)

  Jenna Voutsinas, Lynne R Wilkens, Adrian Franke, Thomas M Vogt, Lance A Yokochi, Robert Decker, Loïc Le Marchand
• Original article: Single measures of performance do not reflect overall institutional quality in colorectal cancer surgery (16 February, 2012)

  Alex M Almoudaris, Elaine M Burns, Alex Bottle, Paul Aylin, Ara Darzi, Charles Vincent, Omar Faiz

Pancreas

• Original article: Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice (5 April, 2012)

  Matthias Sendler, Annegret Dummer, Frank U Weiss, Burkhard Krüger, Thomas Wartmann, Karin Scharffetter-Kochanek, Nico van Rooijen, Sudarshan Ravi Malla, Ali Aghdassi, Walter Halangk, Markus M Lerch, Julia Mayerle

Hepatology

• Original article: HDGF-related protein-3 is required for anchorage-independent survival and chemoresistance in hepatocellular carcinomas (5 April, 2012)

  Qianyi Xiao, Kai Qu, Chenji Wang, Yahui Kong, Chao Liu, Deke Jiang, Hexige Saiyin, Fan Jia, Canrong Ni, Taoyang Chen, Yuanyuan Zhang, Pingzhao Zhang, Wenxin Qin, Qingwen Sun, Hongyang Wang, Qing Yi, Jun Liu, Haojie Huang, Long Yu
• Original article: Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis (25 May, 2012)

  Silvia Affò, Marlene Dominguez, Juan José Lozano, Pau Sancho-Bru, Daniel Rodrigo-Torres, Oriol Morales-Ibanez, Montserrat Moreno, Cristina Millán, Aurora Loaeza-del-Castillo, José Altamirano, Juan Carlos García-Pagán, Vicente Arroyo, Pere Ginès, Juan Caballería, Robert F Schwabe, Ramon Bataller