Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene

Tsunamasa Watanabe; Fuminaka Sugauchi; Yasuhito Tanaka; Kentaro Matsuura; Hiroshi Yatsuhashi; Shuko Murakami; Sayuki Iijima; Etsuko Iio; Masaya Sugiyama; Takashi Shimada; Masakazu Kakuni; Michinori Kohara; Masashi Mizokami

doi:10.1136/gutjnl-2012-302553

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Hepatology

Original article

Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene

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	Abstract	Full	Pdf
Nov 2012	403	158	139
Dec 2012	189	69	46
Jan 2013	111	67	38
Feb 2013	53	62	27
Mar 2013	55	59	225
Apr 2013	44	48	34
May 2013	29	20	13
Jun 2013	30	34	14
Jul 2013	24	29	18
Aug 2013	2056	135	143
Sep 2013	1210	76	95
Oct 2013	509	16	32
Nov 2013	485	15	23
Dec 2013	343	13	21
Jan 2014	190	22	14
Feb 2014	59	13	10
Mar 2014	57	22	17
Apr 2014	59	20	14
May 2014	29	15	14
Jun 2014	46	7	8
Jul 2014	35	16	8
Aug 2014	22	11	10
Sep 2014	19	5	2
Oct 2014	22	9	13
Nov 2014	28	8	12
Dec 2014	13	6	7
Jan 2015	27	4	13
Feb 2015	16	3	11
Mar 2015	19	8	6
Apr 2015	18	5	15
May 2015	15	12	6
Jun 2015	14	2	7
Jul 2015	23	2	4
Aug 2015	16	3	11
Sep 2015	16	10	1
Oct 2015	10	4	1
Nov 2015	10	5	10
Dec 2015	33	17	10
Jan 2016	27	18	11
Feb 2016	13	4	10
Mar 2016	14	4	20
Apr 2016	20	4	6
May 2016	8	2	8
Jun 2016	18	7	4
Jul 2016	24	9	9
Aug 2016	23	4	2
Sep 2016	32	13	7
Oct 2016	32	15	16
Nov 2016	25	7	6
Dec 2016	20	4	0
Jan 2017	27	5	6
Feb 2017	3	3	4
Mar 2017	4	15	4
Apr 2017	3	15	3
May 2017	4	22	1
Jun 2017	6	13	4
Jul 2017	12	10	11
Aug 2017	33	24	3
Sep 2017	15	15	1
Oct 2017	27	25	5
Nov 2017	24	18	7
Dec 2017	13	13	4
Jan 2018	25	19	1
Feb 2018	23	14	2
Mar 2018	24	20	1
Apr 2018	27	25	1
May 2018	28	26	4
Jun 2018	41	35	1
Jul 2018	30	13	9
Aug 2018	12	9	3
Sep 2018	17	12	6
Oct 2018	18	12	9
Nov 2018	37	37	4
Dec 2018	37	37	2
Jan 2019	39	35	3
Feb 2019	33	28	3
Mar 2019	27	26	11
Apr 2019	12	9	7
May 2019	5	5	9
Jun 2019	6	6	5
Jul 2019	6	6	6
Aug 2019	15	14	8
Sep 2019	13	9	4
Oct 2019	12	9	4
Nov 2019	6	6	2
Dec 2019	14	10	6
Jan 2020	17	12	17
Feb 2020	14	14	8
Mar 2020	24	24	5
Apr 2020	5	5	6
May 2020	7	6	4
Jun 2020	13	13	5
Jul 2020	8	8	0
Aug 2020	0	0	6
Sep 2020	28	23	6
Oct 2020	22	18	4
Nov 2020	23	9	6
Dec 2020	19	10	6
Jan 2021	11	6	5
Feb 2021	6	7	2
Mar 2021	6	6	3
Apr 2021	3	3	2
May 2021	12	11	10
Jun 2021	12	10	8
Jul 2021	4	4	8
Aug 2021	9	8	5
Sep 2021	11	11	16
Oct 2021	9	5	21
Nov 2021	7	7	25
Dec 2021	12	10	2
Jan 2022	13	13	16
Feb 2022	22	23	4
Mar 2022	20	18	3
Apr 2022	24	19	5
May 2022	60	60	19
Jun 2022	33	33	7
Jul 2022	25	21	2
Aug 2022	18	16	9
Sep 2022	37	36	13
Oct 2022	48	44	7
Nov 2022	23	22	13
Dec 2022	8	8	3
Jan 2023	10	6	5
Feb 2023	3	3	2
Mar 2023	9	5	1
Apr 2023	2	2	3
May 2023	3	2	9
Jun 2023	3	3	1
Jul 2023	5	5	11
Aug 2023	3	3	6
Sep 2023	3	3	1
Oct 2023	7	5	3
Nov 2023	8	9	7
Dec 2023	11	11	5
Jan 2024	15	15	9
Feb 2024	12	12	6
Mar 2024	8	5	3
Total	7986	2353	1708

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