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  1. K Etherson1,
  2. A Davidson1,
  3. Y Yiannakou1,
  4. J Mason2
  1. 1 Department of Surgery, University Hospital of North Durham, County Durham and Darlington NHS Foundation Trust, County Durham, UK
  2. 2 Wolfson Research Institute, Durham University, County Durham, UK


Introduction Sacral nerve stimulation testing (TSNS) for chronic constipation is not accurately predictive of a long-term response1. The decision to implant a permanent device relies on these results.

Aims/Background We recognised that the testing stimulator was an analogue device with potentially inaccurate dial settings. We sought verification of the output waveform.

Method 19 test stimulators were connected to a cross-calibrated oscilloscope. The output Frequency (f), and Pulse Width (pw) of the waveforms generated were measured according to: run 1) the physician's best attempt to set the dials correctly (pw=210 µ Sec, f=14 Hz), and run 2) the closest dial increment to these settings (pw=200 µ Sec, f=10 Hz). Output Voltage (V) was measured in run 3 at dial increments of 0V, 1V, 2V, 5V, and 10V.

Results We assumed an acceptable margin of error of 20% in runs 1 and 2, and 0.5V in run 3.

There was a marked range of frequency values; run 1) 10.6 to 29.0 Hz (26% failed), and run 2) 7.9 to 13.0 Hz (11% failed).

Findings for pulse width were similarly variable; run 1) 242 to 326 µ Sec (89% failed), and run 2)215 to 274 µ Sec (63% failed).

All devices had a residual positive voltage at zero(range:0.29 to 1.00V), and the failure rates at 0,1,2,5 and 10V were 53%, 100%, 100%, 68% and 47% respectively.

Conclusion All fields of clinical practice and research have their instrumentation which requires calibration to provide verifiable readings. Failure to calibrate during TSNS results in patients receiving variable stimulation, potentially reducing the clarity of research findings, and may be a factor in the poor predictive power of testing in chronic constipation.

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