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THE APPROPRIATENESS OF PPI PRESCRIPTION IN A GENERAL MEDICAL COHORT
  1. N Moran,
  2. E Jones,
  3. A O'Toole,
  4. S Patchett,
  5. G Harewood,
  6. F Murray
  1. Department of Gastroenterology and Hepatology, Beaumont Hospital, Dublin, Ireland

Abstract

Introduction Proton pump inhibitors (PPIs) are one of the most commonly prescribed groups of drug in Ireland, and at great expense. In addition PPIs are associated with side effects. Anecdotally, many patients receive regular PPI treatment for poorly defined reasons and for conditions where PPIs have not been shown to be of benefit.

Aims/Background To assess practices surrounding PPI prescription in acute medical admissions in a tertiary referral centre.

Method In the emergency department, we obtained details of all non-elective admissions during one week from 6th–10th February 2013. We reviewed admission notes to document PPI prescription prior to admission and questioned patients as to whether they knew the duration and indication of their PPI treatment.

Results In total, 102 patients were included, 54 female (53%) and 48 male (47%). The median age was 67 (range 19–88 years). 35.4 % (n=36) were on a PPI on admission. The indication for PPI treatment was documented in 8.3 % of patients. 7.8 % (n=8) were commenced on a PPI on admission. Following patient interviews, 35% (n=12) identified a reason for ongoing PPI use. 65% (n=24) were unclear as to why they were taking a PPI regularly. Indications included GI protection and subjective symptoms of dyspepsia.

Conclusion As PPI use has become more widespread, and in particular with the recent advent of OTC formulations, doctors are less likely to question the original indication for patients' prescription. In fact, patients themselves are often unaware of why they are taking these particular medications.

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