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Gut 63:205 doi:10.1136/gutjnl-2013-304988
  • PostScript
  • Letter

Obesity and colorectal cancer

  1. Jesper Lagergren2
  1. 1Leeds Institute of Biomedical & Clinical Sciences, St James's University Hospital, Leeds, UK
  2. 2Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden and Division of Cancer Studies, King's College, London, UK
  1. Correspondence to Dr Mark Hull, St James's University, Leeds Institute of Biomedical & Clinical Sciences, Leeds LS97TF, UK; M.A.Hull{at}leeds.ac.uk
  • Received 28 March 2013
  • Accepted 29 March 2013
  • Published Online First 3 May 2013

Bardou et al are to be congratulated on producing an excellent and comprehensive review of the existing literature on the link between excess body weight and colorectal neoplasia. The authors included the current literature on the effect of bariatric surgery on subsequent cancer risk and rightly pointed out that the previous small studies have lacked sufficient statistical power to determine accurately whether colorectal cancer (CRC) risk or mortality is impacted by bariatric surgery.1 However, Bardou et al conclude their Abstract by posing a provocative question regarding a possible role for bariatric surgery in the reduction of CRC risk, with the tacit …


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