Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

Thomas Sonnweber; David Nachbaur; Andrea Schroll; Manfred Nairz; Markus Seifert; Egon Demetz; David Haschka; Anna-Maria Mitterstiller; Axel Kleinsasser; Martin Burtscher; Susanne Trübsbach; Anthony T Murphy; Victor Wroblewski; Derrick R Witcher; Katarzyna Mleczko-Sanecka; Chiara Vecchi; Martina U Muckenthaler; Antonello Pietrangelo; Igor Theurl; Günter Weiss

doi:10.1136/gutjnl-2013-305317

Article info

Hepatology

Original article

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

Authors

Thomas Sonnweber Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
David Nachbaur Department of Internal Medicine V, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Andrea Schroll Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Manfred Nairz Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Markus Seifert Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Egon Demetz Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
David Haschka Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Anna-Maria Mitterstiller Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Axel Kleinsasser Department of Anaesthesia and Intensive Care Medicine, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Martin Burtscher Department of Sports Medicine, Leopold-Franzens University, Innsbruck, Austria PubMed articles Google scholar articles
Susanne Trübsbach Department of Anaesthesia and Intensive Care Medicine, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Anthony T Murphy Biotechnology Discovery Research, Lilly Research Laboratories, Indianapolis, Indiana, USA PubMed articles Google scholar articles
Victor Wroblewski Biotechnology Discovery Research, Lilly Research Laboratories, Indianapolis, Indiana, USA PubMed articles Google scholar articles
Derrick R Witcher Biotechnology Discovery Research, Lilly Research Laboratories, Indianapolis, Indiana, USA PubMed articles Google scholar articles
Katarzyna Mleczko-Sanecka Department of Pediatric Oncology, Haematology and Immunology, University Hospital of Heidelberg, Heidelberg, Germany PubMed articles Google scholar articles
Chiara Vecchi Division of Internal Medicine 2 and Center for Hemochromatosis, “Mario Coppo” Liver Research Center, University Hospital of Modena, Modena, Italy PubMed articles Google scholar articles
Martina U Muckenthaler Department of Pediatric Oncology, Haematology and Immunology, University Hospital of Heidelberg, Heidelberg, Germany PubMed articles Google scholar articles
Antonello Pietrangelo Division of Internal Medicine 2 and Center for Hemochromatosis, “Mario Coppo” Liver Research Center, University Hospital of Modena, Modena, Italy PubMed articles Google scholar articles
Igor Theurl Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Günter Weiss Department of Internal Medicine VI, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles

Correspondence to Professors Guenter Weiss and Igor Theurl, Department of Internal Medicine VI, Infectious Diseases, Immunology, Rheumatology, Pneumology, Anichstrasse 35, Medical University Innsbruck, Innsbruck A-6020, Austria; igor.theurl{at}i-med.ac.at or guenter.weiss{at}i-med.ac.at

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Citation

Sonnweber T, Nachbaur D, Schroll A, et al

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

Gut 2014;63:1951-1959.

Publication history

Received May 22, 2013
Revised February 6, 2014
Accepted February 7, 2014
First published March 5, 2014.

Online issue publication

April 18, 2016

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