Genetic variants in CDC42 and NXPH1 as susceptibility factors for constipation and diarrhoea predominant irritable bowel syndrome

Mira M Wouters; Diether Lambrechts; Michael Knapp; Isabelle Cleynen; Peter Whorwell; Lars Agréus; Aldona Dlugosz; Peter Thelin Schmidt; Jonas Halfvarson; Magnus Simrén; Bodil Ohlsson; Pontus Karling; Sander Van Wanrooy; Stéphanie Mondelaers; Severine Vermeire; Greger Lindberg; Robin Spiller; George Dukes; Mauro D'Amato; Guy Boeckxstaens

doi:10.1136/gutjnl-2013-304570

Article info

Neurogastroenterology

Original article

Genetic variants in CDC42 and NXPH1 as susceptibility factors for constipation and diarrhoea predominant irritable bowel syndrome

Authors

Mira M Wouters Translational Research Center for Gastrointestinal Disorders, Leuven University, Leuven, Belgium PubMed articles Google scholar articles
Diether Lambrechts Vesalius Research Center, VIB, Leuven University, Leuven, Belgium Laboratory for Translational Genetics, Department of Oncology, Leuven University, Leuven, Belgium PubMed articles Google scholar articles
Michael Knapp Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany PubMed articles Google scholar articles
Isabelle Cleynen Translational Research Center for Gastrointestinal Disorders, Leuven University, Leuven, Belgium PubMed articles Google scholar articles
Peter Whorwell Department of Medicine, University of Manchester, Manchester, UK PubMed articles Google scholar articles
Lars Agréus Centre for Family Medicine, Karolinska Institutet, Stockholm, Sweden PubMed articles Google scholar articles
Aldona Dlugosz Department of Medicine, Karolinska Institutet, Stockholm, Sweden PubMed articles Google scholar articles
Peter Thelin Schmidt Department of Medicine, Karolinska Institutet, Stockholm, Sweden PubMed articles Google scholar articles
Jonas Halfvarson Department of Internal Medicine, Örebro University Hospital, Örebro, Sweden PubMed articles Google scholar articles
Magnus Simrén Department of Internal Medicine, Gothenburg University, Gothenburg, Sweden PubMed articles Google scholar articles
Bodil Ohlsson Department of Clinical Sciences, Skånes University Hospital, Malmoe, Sweden PubMed articles Google scholar articles
Pontus Karling Department of Medicine, Umeå University, Umeå, Sweden PubMed articles Google scholar articles
Sander Van Wanrooy Translational Research Center for Gastrointestinal Disorders, Leuven University, Leuven, Belgium PubMed articles Google scholar articles
Stéphanie Mondelaers Translational Research Center for Gastrointestinal Disorders, Leuven University, Leuven, Belgium PubMed articles Google scholar articles
Severine Vermeire Translational Research Center for Gastrointestinal Disorders, Leuven University, Leuven, Belgium PubMed articles Google scholar articles
Greger Lindberg Department of Medicine, Karolinska Institutet, Stockholm, Sweden PubMed articles Google scholar articles
Robin Spiller Queen's Medical Centre, Nottingham, UK PubMed articles Google scholar articles
George Dukes Academic DPU, GlaxoSmithKline, Research Triangle Par, North Carolina, USA PubMed articles Google scholar articles
Mauro D'Amato Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden PubMed articles Google scholar articles
Guy Boeckxstaens Translational Research Center for Gastrointestinal Disorders, Leuven University, Leuven, Belgium PubMed articles Google scholar articles

Correspondence to Dr Mira Wouters, Translational Research Center for Gastrointestinal Disorders, Leuven University, Herestraat 49 bus 701, Leuven 3000, Belgium; mira.wouters{at}med.kuleuven.be

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Citation

Wouters MM, Lambrechts D, Knapp M, et al

Genetic variants in CDC42 and NXPH1 as susceptibility factors for constipation and diarrhoea predominant irritable bowel syndrome

Gut 2014;63:1103-1111.

Publication history

Received January 24, 2013
Revised August 19, 2013
Accepted August 21, 2013
First published September 16, 2013.

Online issue publication

April 18, 2016

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