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Footnotes
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Contributors MJJ: Study concept and design, acquisition of data, analysis and interpretation of data, statistical analysis and drafting and revising of the manuscript. JS: Acquisition of data, analysis and interpretation of data, technical support and revising the draft paper. CB: Acquisition of data, technical support and revising the draft paper. RP: Acquisition of data, analysis and interpretation of data, critical revision of the manuscript for important intellectual content, technical and material support. JPHD: Study concept and design, critical revision of the manuscript for important intellectual content, obtained funding and supervised the study.
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Funding Funding for this study was provided by the Institute for Genetic and Metabolic Diseases (Radboudumc).
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Competing interests CB is an employee of Bioscientia/Sonic Healthcare.
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Patient consent Obtained.
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Ethics approval Commissie Mensgebonden Onderzoek (CMO) regio Arnhem-Nijmegen.
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Provenance and peer review Not commissioned; internally peer reviewed.