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Screening for bile acid diarrhoea in suspected irritable bowel syndrome
  1. Imran Aziz1,
  2. Matthew Kurien1,
  3. David S Sanders1,
  4. Alexander C Ford2,3
  1. 1 Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, UK
  2. 2 Leeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK
  3. 3 Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK
  1. Correspondence to Dr Alexander C Ford, Leeds Gastroenterology Institute, Room 125, 4th Floor, Bexley Wing, St. James's University Hospital, Beckett Street, Leeds LS9 7TF, UK; alexf12399{at}yahoo.com

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We read the paper by Bajor et al with interest.1 The authors demonstrated that 18% of patients who meet criteria for IBS may have underlying bile acid diarrhoea (BAD), using 23-seleno-25-homo-tauro-cholic acid (SeHCAT) scanning. This issue has been the subject of a previous systematic review and meta-analysis2 which reported that up to 30% of individuals with IBS had evidence of idiopathic BAD. However, many of the included studies were retrospective, and few used accepted symptom-based criteria to define the presence of IBS, underlining the importance of the data from Bajor et al 1 who recruited a well characterised and rigorously defined cohort of patients meeting the Rome II criteria for IBS.

We therefore congratulate the authors …

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