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We read the paper by Bajor et al with interest.1 The authors demonstrated that 18% of patients who meet criteria for IBS may have underlying bile acid diarrhoea (BAD), using 23-seleno-25-homo-tauro-cholic acid (SeHCAT) scanning. This issue has been the subject of a previous systematic review and meta-analysis2 which reported that up to 30% of individuals with IBS had evidence of idiopathic BAD. However, many of the included studies were retrospective, and few used accepted symptom-based criteria to define the presence of IBS, underlining the importance of the data from Bajor et al 1 who recruited a well characterised and rigorously defined cohort of patients meeting the Rome II criteria for IBS.
We therefore congratulate the authors …