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OC-073 The First Multicentre Experience from The UK and Ireland of the Use of the Hot Axios System for Transluminal Drainage of Pancreatic Fluid Collections
  1. SV Venkatachalapathy1,
  2. A Makin2,
  3. SP Pereira3,
  4. GJ Johnson3,
  5. N Bekkali3,
  6. I Penman4,
  7. KW Oppong5,
  8. MK Nayar5,
  9. NR Carroll6,
  10. EM Godfrey6,
  11. BM Ryan7,
  12. V Parihar7,
  13. CJ McKay8,
  14. MT Huggett1
  1. 1Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds
  2. 2Gastroenterology, Central Manchester University Hospitals NHS Foundation Trust, Manchester
  3. 3Gastroenterology, University College Hospitals NHS Foundation Trust, London
  4. 4Gastroenterology, Western General Hospital and Royal Infirmary, Edinburgh
  5. 5Gastroenterology, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle
  6. 6Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
  7. 7Gastroenterology, The Adelaide and Meath Hospital, Dublin, Ireland
  8. 8Pancreatic Surgery, Glasgow Royal Infirmary, Glasgow, UK

Abstract

Introduction Pancreatic fluid collections (PFC) are a common local complication of pancreatitis with incidences of 5–16% and 20–40% in acute and chronic pancreatitis, respectively.1 Classification of PFC includes acute peripancreatic fluid collection, pancreatic pseudocyst, acute necrotic collection and walled-off necrosis (WON). A new lumen-apposing, covered self-expanding metal stent on a catheter-based delivery system (Hot AXIOS, Boston Scientific) may have higher technical success rates, easier deployment and lower migration than plastic stents. We present the first multicentre prospective case series from the UK and Ireland to assess success and complication rates associated with Hot AXIOS stent for the drainage of PFC.

Methods All adult patients who had Hot AXIOS stent placement for PFC from July 2015-February 2016 were included. Eight centres participated (London, Glasgow, Edinburgh, Newcastle, Cambridge, Manchester, Dublin and Leeds). All patients had CT of the PFC prior to placement. Data including technical success, resolution of collection, complications and stent migration were collected.

Results Forty patients were treated with a single Hot AXIOS stent in each case. The median age was 57 years (range 31–78). 25 were male and 15 female. Indications were WON (24), pseudocyst (15) and abscess.1 The median size of the PFC was 11 cm (4–20 cm). Thirty-eight patients (95%) had trans-gastric stents, 1 had trans-duodenal and 1 had a trans-oesophageal stent. Procedures were technically successful in all patients.

Of 22 patients with available follow-up data to date, the collection resolved in 19 (86%) and reduced in size in 3 (14%). The median time to resolution was 36 (7–208) days. Twelve patients (30%) had 33 necrosectomies and/or endoscopic lavage following stent insertion.

Stents migrated out in 2 patients and was displaced during necrosectomy in 1. Serious adverse events occurred in 1/40 (2.5%): a small bowel obstruction resulting from stent migration, managed surgically. There was no procedure related or 30 day mortality (data available in 27 patients).

Conclusion This multicentre case series demonstrates that the Hot AXIOS system is safe and effective in draining PFC with a technical success rate of 100% and low serious adverse event rate.

Reference 1 Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis—2012: Revision of the Atlanta classification and definitions by international consensus. Gut 2013.

Disclosure of Interest None Declared

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