Gut: 66 (12)

Leading article

Illusions regarding Helicobacter pylori clinical trials and treatment guidelines
(21 September, 2017)
David Y Graham

Commentaries

Gastro-oesophageal reflux events: just another trigger in chronic cough? (25 April, 2017)
L A Houghton, J A Smith
Janus-like monocytes regulate postoperative ileus (14 June, 2017)
Allan McI Mowat
SENP1 activity sustains cancer stem cell in hypoxic HCC (13 April, 2017)
Alice Conigliaro, Marco Tripodi, Maurizio Parola
Prioritising treatment among people who inject drugs in order to eliminate hepatitis C: addressing reluctance with sound economic analyses (26 August, 2016)
Yvan J-F Hutin, Stefan Z Wiktor

Endoscopy news

Lumen-apposing metal stents (LAMS) for pancreatic fluid collection (PFC) drainage: may not be business as usual (31 August, 2016)
Ji Young Bang, Muhammad Hasan, Udayakumar Navaneethan, Robert Hawes, Shyam Varadarajulu

Oesophagus

Original article: Determinants of reflux-induced chronic cough (15 March, 2017)
Thomas V K Herregods, Ans Pauwels, Jafar Jafari, Daniel Sifrim, Albert J Bredenoord, Jan Tack, André J P M Smout

Inflammatory bowel disease

Original article: Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC (2 September, 2016)
Jean-Frédéric Colombel, Mary E Keir, Alexis Scherl, Rui Zhao, Gert de Hertogh, William A Faubion, Timothy T Lu
Original article: Alterations in the epithelial stem cell compartment could contribute to permanent changes in the mucosa of patients with ulcerative colitis (1 November, 2016)
Isabella Dotti, Rut Mora-Buch, Elena Ferrer-Picón, Núria Planell, Peter Jung, M Carme Masamunt, Raquel Franco Leal, Javier Martín de Carpi, Josep Llach, Ingrid Ordás, Eduard Batlle, Julián Panés, Azucena Salas

Coeliac disease

Original Article: ROC-king onwards: intraepithelial lymphocyte counts, distribution & role in coeliac disease mucosal interpretation (11 September, 2017)
Kamran Rostami, Michael N Marsh, Matt W Johnson, Hamid Mohaghegh, Calvin Heal, Geoffrey Holmes, Arzu Ensari, David Aldulaimi, Brigitte Bancel, Gabrio Bassotti, Adrian Bateman, Gabriel Becheanu, Anna Bozzola, Antonio Carroccio, Carlo Catassi, Carolina Ciacci, Alexandra Ciobanu, Mihai Danciu, Mohammad H Derakhshan, Luca Elli, Stefano Ferrero, Michelangelo Fiorentino, Marilena Fiorino, Azita Ganji, Kamran Ghaffarzadehgan, James J Going, Sauid Ishaq, Alessandra Mandolesi, Sherly Mathews, Roxana Maxim, Chris J Mulder, Andra Neefjes-Borst, Marie Robert, Ilaria Russo, Mohammad Rostami-Nejad, Angelo Sidoni, Masoud Sotoudeh, Vincenzo Villanacci, Umberto Volta, Mohammad R Zali, Amitabh Srivastava

Gut microbiota

Original article: Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease (30 September, 2016)
Robert Häsler, Raheleh Sheibani-Tezerji, Anupam Sinha, Matthias Barann, Ateequr Rehman, Daniela Esser, Konrad Aden, Carolin Knecht, Berenice Brandt, Susanna Nikolaus, Sascha Schäuble, Christoph Kaleta, Andre Franke, Christoph Fretter, Werner Müller, Marc-Thorsten Hütt, Michael Krawczak, Stefan Schreiber, Philip Rosenstiel

Neurogastroenterology

Original Article: CCR2-dependent monocyte-derived macrophages resolve inflammation and restore gut motility in postoperative ileus (14 June, 2017)
Giovanna Farro, Michelle Stakenborg, Pedro J Gomez-Pinilla, Evelien Labeeuw, Gera Goverse, Martina Di Giovangiulio, Nathalie Stakenborg, Elisa Meroni, Francesca D’Errico, Yvon Elkrim, Damya Laoui, Zofia M Lisowski, Kristin A Sauter, David A Hume, Jo A Van Ginderachter, Guy E Boeckxstaens, Gianluca Matteoli
Original Article:
Irf4-dependent CD103⁺CD11b⁺ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus
(14 June, 2017)
Judith-Mira Pohl, Sebastian Gutweiler, Stephanie Thiebes, Julia K Volke, Ludger Klein-Hitpass, Denise Zwanziger, Matthias Gunzer, Steffen Jung, William W Agace, Christian Kurts, Daniel Robert Engel
Original article: Stress activates pronociceptive endogenous opioid signalling in DRG neurons during chronic colitis (2 September, 2016)
Raquel Guerrero-Alba, Eduardo E Valdez-Morales, Nestor N Jimenez-Vargas, Cintya Lopez-Lopez, Josue Jaramillo-Polanco, Takanobu Okamoto, Yasmin Nasser, Nigel W Bunnett, Alan E Lomax, Stephen J Vanner

Colon

Original article: Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates (8 September, 2016)
Chelsie K Sievers, Luli S Zou, Perry J Pickhardt, Kristina A Matkowskyj, Dawn M Albrecht, Linda Clipson, Jeffery W Bacher, B Dustin Pooler, Fouad J Moawad, Brooks D Cash, Mark Reichelderfer, Tien N Vo, Michael A Newton, Bret R Larget, Richard B Halberg
Original article: BCL-2 system analysis identifies high-risk colorectal cancer patients (23 September, 2016)
Andreas U Lindner, Manuela Salvucci, Clare Morgan, Naser Monsefi, Alexa J Resler, Mattia Cremona, Sarah Curry, Sinead Toomey, Robert O'Byrne, Orna Bacon, Michael Stühler, Lorna Flanagan, Richard Wilson, Patrick G Johnston, Manuel Salto-Tellez, Sophie Camilleri-Broët, Deborah A McNamara, Elaine W Kay, Bryan T Hennessy, Pierre Laurent-Puig, Sandra Van Schaeybroeck, Jochen H M Prehn

Hepatology

Original article: SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop (3 March, 2017)
Chun-Ping Cui, Carmen Chak-Lui Wong, Alan Ka-Lun Kai, Daniel Wai-Hung Ho, Eunice Yuen-Ting Lau, Yu-Man Tsui, Lo-Kong Chan, Tan-To Cheung, Kenneth Siu-Ho Chok, Albert C Y Chan, Regina Cheuk-Lam Lo, Joyce Man-Fong Lee, Terence Kin-Wah Lee, Irene Oi Lin Ng
Original article: Lysophosphatidylcholine acyltransferase 1 is downregulated by hepatitis C virus: impact on production of lipo-viro-particles (31 August, 2016)
Frauke Beilstein, Matthieu Lemasson, Véronique Pène, Dominique Rainteau, Sylvie Demignot, Arielle R Rosenberg

Recent advances in basic science

A genetic roadmap of pancreatic cancer: still evolving (9 October, 2017)
Faiyaz Notta, Stephan A Hahn, Francisco X Real

Recent advances in clinical practice

Early intervention in Crohn’s disease: towards disease modification trials (5 September, 2017)
Silvio Danese, Gionata Fiorino, Laurent Peyrin-Biroulet

Book review

The principles and practice of nutritional support (12 October, 2016)
Simon Lal

JournalScan

GI highlights from the literature (10 November, 2017)
Mairi H McLean

Postscript

Letter: Re-evaluation of the role of lumen-apposing metal stents (LAMS) for pancreatic ﬂuid collection drainage (17 March, 2017)
Huiyun Zhu, Han Lin, Zhendong Jin, Yiqi Du
Letter: Response to letter to the editor (12 January, 2017)
Ji Young Bang, Shyam Varadarajulu
Letter: Epithelial organoid cultures from patients with ulcerative colitis and Crohn's disease: a truly long-term model to study the molecular basis for inflammatory bowel disease? (3 February, 2017)
Manuel Noben, Bram Verstockt, Magali de Bruyn, Nikolai Hendriks, Gert Van Assche, Séverine Vermeire, Catherine Verfaillie, Marc Ferrante
Letter:
In vitro and in silico evidence against a significant effect of the SPINK1 c.194G>A variant on pre-mRNA splicing
(20 March, 2017)
Hao Wu, Arnaud Boulling, David N Cooper, Zhao-Shen Li, Zhuan Liao, Jian-Min Chen, Claude Férec

Editor’s quiz: GI snapshot

Thinking out of the Gut: a case of obscure lower GI bleeding
(13 December, 2016)
Frederick H Koh, Hian-Li Chan, Fredrik Petersson, Choon-Seng Chong

Correction

Correction: Quality standards in upper gastrointestinal endoscopy: a position statement of the British Society of Gastroenterology (BSG) and Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland (AUGIS) (10 November, 2017)

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Table of contents

December 2017 - Volume 66 - 12

Leading article

Commentaries

Endoscopy news

Oesophagus

Inflammatory bowel disease

Coeliac disease

Gut microbiota

Neurogastroenterology

Colon

Hepatology

Recent advances in basic science

Recent advances in clinical practice

Book review

JournalScan

Postscript

Editor’s quiz: GI snapshot

Correction

Issue Information

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Table of contents

December 2017 - Volume 66 - 12

Leading article

Commentaries

Endoscopy news

Oesophagus

Inflammatory bowel disease

Coeliac disease

Gut microbiota

Neurogastroenterology

Colon

Hepatology

Recent advances in basic science

Recent advances in clinical practice

Book review

JournalScan

Postscript

Editor’s quiz: GI snapshot

Correction

Issue Information