Background Granular cell tumours (GCT) are soft tissue tumours that present in the skin/oral cavity, with 5% presenting in the gastrointestinal tract.

We present a local case series, illustrating endoscopic, ultrasonograpic and histological appearances of GCT in the oesophagus and subsequent management.

Aim Describing clinicopathological characteristics of oesophageal GCT with follow up.

Method Retrospective case notes review.

Results Case 1-A 51 year old female presented with dysphagia. OGD showed two small oesophageal lesions (<1 cm) at 30/32 cm. Endoscopic Ultrasound (EUS) revealed a submucosal lesion. MDT discussion recommended a conservative approach, with yearly endoscopy and EUS.

Case 2-A 55 year old female presented with lethargy. OGD showed a small oesophageal lesion (0.6 cm) at 34 cm. EUS revealed a mucosal lesion with minimal submucosal involvement. MDT discussion for both patients recommended a conservative approach, follow up for >3 years has shown no ultrasonographic change.

Case 3-A 31 year old male presented with dyspepsia. OGD showed a small oesophageal lesion (<1 cm) at 34 cm. EUS revealed a submucosal lesion. MDT discussion adopted a conservative approach, with yearly endoscopy and EUS, and follow up at 2 years has shown no ultrasonographic change.

Case 4-A 67 year old female presented with dyspepsia. OGD revealed a small oesophageal lesion (<1 cm) in the distal oesophagus. EUS is awaited.

Conclusions GCT’s are rare, with low malignant potential. They are usually asymptomatic, and have a classical endoscopic appearance of a firm, yellow, submucosal lesion. EUS is critical in staging, with MDT discussion. A conservative approach appears justified, with yearly endoscopy and EUS for surveillance.