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Original article
Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

Authors

  • Pål Møller Department of Medical Genetics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway Center for Hereditary Tumors, HELIOS-Klinikum Wuppertal, University of Witten-Herdecke, Wuppertal, Germany PubMed articlesGoogle scholar articles
  • Toni T Seppälä Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland PubMed articlesGoogle scholar articles
  • Inge Bernstein The Danish Hereditary Non-polyposis Colorectal Cancer Register, Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark PubMed articlesGoogle scholar articles
  • Elke Holinski-Feder Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Ziemssenstr, Germany MGZ – Medizinisch Genetisches Zentrum, Munich, Germany PubMed articlesGoogle scholar articles
  • Paulo Sala Unit of Hereditary Digestive Tract Tumors IRCCS Istituto Nazionale Tumori Milan, Milano, Italy PubMed articlesGoogle scholar articles
  • D Gareth Evans Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, London, UK Manchester Centre for Genomic Medicine, University of Manchester, London, UK PubMed articlesGoogle scholar articles
  • Annika Lindblom Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden PubMed articlesGoogle scholar articles
  • Finlay Macrae Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melborne, Australia Department of Medicine, Melbourne University, Melborne, Australia PubMed articlesGoogle scholar articles
  • Ignacio Blanco Hereditary Cancer Program, Institut Català d’Oncologia-IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Rolf H Sijmons Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Jacqueline Jeffries Division of Cancer and Genetics, Institute of Medical Genetics, Cardiff University School of Medicine, Heath Park, UK PubMed articlesGoogle scholar articles
  • Hans F A Vasen Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • John Burn Institute of Genetic Medicine Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • Sigve Nakken Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway PubMed articlesGoogle scholar articles
  • Eivind Hovig Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway Institute of Cancer Genetics and Informatics, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway Department of Informatics, University of Oslo, Olso, Norway PubMed articlesGoogle scholar articles
  • Einar Andreas Rødland Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway PubMed articlesGoogle scholar articles
  • Kukatharmini Tharmaratnam Department of Mathematics and Statistics, Lancaster University, Lancaster, UK PubMed articlesGoogle scholar articles
  • Wouter H de Vos tot Nederveen Cappel Department of Gastroenterology and Hepatology, Isala Clinics, Zwolle, The Netherlands PubMed articlesGoogle scholar articles
  • James Hill Department of Surgery, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester, London, UK PubMed articlesGoogle scholar articles
  • Juul T Wijnen Department of Clinical Genetics and Department of Human Genetics Leiden, University Medical Centre, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Mark A Jenkins Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia PubMed articlesGoogle scholar articles
  • Kate Green Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, London, UK Manchester Centre for Genomic Medicine, University of Manchester, London, UK PubMed articlesGoogle scholar articles
  • Fiona Lalloo Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, London, UK Manchester Centre for Genomic Medicine, University of Manchester, London, UK PubMed articlesGoogle scholar articles
  • Lone Sunde Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark Department of Biomedicine, Aarhus University, Aarhus, Denmark PubMed articlesGoogle scholar articles
  • Miriam Mints Department of Women’s and Children’s health, Division of Obstetrics and Gyneacology, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden PubMed articlesGoogle scholar articles
  • Lucio Bertario Unit of Hereditary Digestive Tract Tumors IRCCS Istituto Nazionale Tumori Milan, Milano, Italy PubMed articlesGoogle scholar articles
  • Marta Pineda Hereditary Cancer Program, Institut Català d’Oncologia-IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Matilde Navarro Hereditary Cancer Program, Institut Català d’Oncologia-IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Monika Morak Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Ziemssenstr, Germany MGZ – Medizinisch Genetisches Zentrum, Munich, Germany PubMed articlesGoogle scholar articles
  • Laura Renkonen-Sinisalo Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland PubMed articlesGoogle scholar articles
  • Mev Dominguez Valentin Department of Medical Genetics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway PubMed articlesGoogle scholar articles
  • Ian M Frayling PubMed articlesGoogle scholar articles
  • John-Paul Plazzer Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melborne, Australia PubMed articlesGoogle scholar articles
  • Kirsi Pylvanainen Department of Education and Science, Central Finland Health Care District, yväskylä, Finland PubMed articlesGoogle scholar articles
  • Maurizio Genuardi Institute of Genomic Medicine, "A. Gemelli" Faculty of Medicine, Catholic University of the Sacred Heart, Rome, Italy PubMed articlesGoogle scholar articles
  • Jukka-Pekka Mecklin University of Eastern Finland, Kuopio, Finland PubMed articlesGoogle scholar articles
  • Gabriela Moeslein PubMed articlesGoogle scholar articles
  • Julian R Sampson Division of Cancer and Genetics, Institute of Medical Genetics, Cardiff University School of Medicine, Heath Park, UK PubMed articlesGoogle scholar articles
  • Gabriel Capella Hereditary Cancer Program, Institut Català d’Oncologia-IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain Center for Hereditary Tumors, HELIOS-Klinikum Wuppertal, University of Witten-Herdecke, Wuppertal, Germany PubMed articlesGoogle scholar articles
  • in collaboration with The Mallorca Group
    Google scholar articles
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Citation

Møller P, Seppälä TT, Bernstein I in collaboration with The Mallorca Group, et al
Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
Gut 2018;67:1306-1316.

Publication history

  • Received February 28, 2017
  • Revised May 9, 2017
  • Accepted May 10, 2017
  • First published July 28, 2017.
Online issue publication 
June 09, 2020

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/