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Hereditary non-polyposis colorectal cancer: clinical and molecular evidence for a new entity of hereditary colorectal cancer
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  • Published on:
    A new entity of hereditary colorectal cancer

    Dear Editor,

    Mueller-Koch et al. in Gut 2005 June 14th (Epub) describe clinical and molecular evidence for a 'new entity' of hereditary colorectal cancer. Clustering of colorectal cancer (CRC) within families has been known for some time [1] and it is not surprising that some such families will meet the Amsterdam Criteria (AC) even though they do not carry a germline mutation in a DNA mismatch repair gene. It has bee...

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    Conflict of Interest:
    None declared.