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Common pathways in inflammatory diseases revealed by genomics
  1. Dunecan C O Massey (dcom2{at}cam.ac.uk)
  1. IBD Genetics Research Group, Addenbrooke's Hospital and University of Cambridge, Cambridge, United Kingdom
    1. Miles Parkes (miles.parkes{at}addenbrookes.nhs.uk)
    1. IBD Genetics Research Group, Addenbrooke's Hospital and University of Cambridge, Cambridge, United Kingdom

      Abstract

      The past 12 months has seen a remarkable revolution in our ability to detect the genetic variants that predispose to common disease, largely due to application of the new methods of genome-wide association (GWA) scanning. This technique is demanding of cutting-edge genotyping and bioinformatic technologies, and requires robust statistical analysis [1], but has already proven itself capable of delivering highly resolved, highly replicated data in the select group of diseases to which it has so far been applied. One of the most dramatically successful of these has been Crohn's disease (CD).

      • Crohn's disease
      • association
      • autophagy
      • genomics
      • pathways

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