Compared with our ancestors, Western societies today lead a lifestyle that is much more sedentary, likely as a result of cultural changes stemming from modern socioeconomic morays. Taking into account differences in body size, our energy expenditure per kilogram of body weight has been estimated to be less than 40% of our prehistoric ancestors. Current estimates suggest that 7 out of 10 adults are inactive or lack adequate conditioning  and this lack of adequate exercise, combined with dietary indiscretion, has contributed to the worldwide epidemic of obesity and nonalcoholic fatty liver disease (NAFLD).
- lifestyle modification
- weight loss