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Insulin resistance and hepatitis C: an evolving story
  1. Mohammed Eslam1,
  2. Mahmoud AboElneen Khattab1,
  3. Stephen A Harrison2
  1. 1Department of Internal Medicine, Minia University, Minia, Egypt
  2. 2Department of Medicine, Division of Gastroenterology and Hepatology, Brooke Army Medical Center, Fort Sam Houston, Texas, USA
  1. Correspondence to Stephen A Harrison, Department of Medicine, Division of Gastroenterology and Hepatology, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA; stephen.harrison{at}amedd.army.mil

Abstract

Insulin resistance and diabetes are inextricably linked to chronic hepatitis C. Our understanding of this relationship continues to improve. This review focuses on the molecular mechanisms relating insulin resistance to hepatitis C with a subsequent overview of the consequences of hepatitis C-associated insulin resistance and diabetes, as well as perspectives for future management.

  • Diabetes mellitus
  • hepatitis
  • C

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Footnotes

  • All authors contributed equally to this article.

  • The opinion of ascertains contained herein are the private views of the authors and are not to be construed as official or reflecting the view of the Department of the Army or the Department of Defense.

  • Competing interests SAH: Research support from Genentech, Merck and Rottapharm; Ad Hoc Advisory Board for Three Rivers Pharmaceuticals; Speaker's bureau for Bristol Myers Squibb.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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