Pathologist's observations have remained central to the evolution of the field of non-alcoholic fatty liver disease, even with the advent of increasingly effective non-invasive markers of advanced fibrosis. As the field matures, the role of pathology has also shifted from being largely descriptive to being confirmatory and diagnostic, as well as providing semi-quantitative evaluation of specific findings, particularly in therapeutic interventional trials. Some newly appreciated histopathological findings will be discussed in this review.
- Non-alcoholic fatty liver disease
- non-alcoholic steatohepatitis
- liver pathology
- liver biopsy
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Competing interests None.
Provenance and peer review Commissioned; externally peer reviewed.