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- Home parenteral nutrition (HPN)
- intestinal transplantation
- intestinal failure
- parenteral nutrition
We thank Abu-Elmagd and Mazariegos1 for their comments and are pleased to have the opportunity to explain our work further.
Our study2 aimed to determine which indications for intestinal transplantation (ITx) were most closely associated with an increased risk of death on home parenteral nutrition (HPN), and whether deaths were due to causes that could be avoided by ITx. The indications for ITx we considered were those described by Medicare, USA, and the American Society of Transplantation; they include objective parameters which allow clear patient identification. Our results confirm that our baseline patient categorisation was appropriate. Ninety-five per cent of patients who were weaned off HPN belonged to the non-candidate group, and 95% of patients who underwent ITx belonged to the candidate group. Survival on HPN was significantly lower in candidates who had HPN failure. Death on HPN was mainly HPN related in candidates, and related to neither HPN …