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Authors' response: clonidine for patients with refractory ascites
  1. Andres Cardenas1,2,
  2. Pere Gines2,3
  1. 1GI Unit, Institut Clinic de Malalties Digestives i Metaboliques, Hospital Clinic, Barcelona, Spain
  2. 2Institut d'Investigacions Biomèdiques August Pi-Sunyer (IDIBAPS), University of Barcelona, Ciber de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain
  3. 3Liver Unit, Institut Clinic de Malalties Digestives i Metaboliques, Hospital Clinic, Barcelona, Spain
  1. Correspondence to Dr Pere Gines, Liver Unit, Institut Clinic de Malalties Digestives, Hospital clinic I provincial, Barcelona, Catalunya, Spain; pgines{at}clinic.ub.es

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We thank Dr Hutchinson and Dr Davies for their comments1 regarding the use of alternative options in patients with cirrhosis and refractory ascites. The use of other potential therapies for patients with refractory ascites is attractive and should perhaps be considered in selected cases. Therapies such as clonidine, a centrally acting α2-agonist and sympatholytic agent, and the use of vasoconstrictors such as midodrine have been …

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