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Evaluating cap-assisted colonoscopy: the relevance of study design
  1. David A Westwood1,
  2. Nicholas Alexakis2,
  3. Saxon J Connor3
  1. 1Department of Surgery, University of Melbourne, Austin Health, Melbourne, Australia
  2. 2Department of Surgery, University of Athens, Hippocratio Hospital, Athens, Greece
  3. 3Department of Surgery, Christchurch Hospital, Canterbury, New Zealand
  1. Correspondence to Dr David Westwood, Department of Surgery, University of Melbourne, Lance Townsend Building, Austin Health, Studley Road, Heidelberg, VIC 3084, Australia; d.westwood{at}doctors.net.uk

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We read with interest the articles by Rastogi et al1 and de Wijkerslooth et al2 describing two randomised-controlled trials (RCTs) of cap-assisted colonoscopy (CAC) versus standard colonoscopy (SC) in Western populations. These trials both used a parallel randomised study design, but yielded conflicting results with regard to adenoma detection rate. While Rastogi et al1 found a significantly higher adenoma detection rate with CAC compared with SC, de Wijkerslooth et al2 demonstrated no difference between the …

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