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The impact of acute kidney injury in cirrhosis: does definition matter?
  1. Alexander L Gerbes
  1. Correspondence to Professor Alexander L Gerbes, Klinikum of the University of Munich, Liver Center Munich, Munich, Germany; gerbes{at}med.uni-muenchen.de

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In their important study, Tsien et al1 demonstrated for the first time that minor increases of serum creatinine have major clinical impact in outpatients with cirrhosis, ascites and normal serum creatinine. Patients with acute kidney injury (AKI) had a slow constant increase of serum creatinine over time and, interestingly, a reduced survival probability. These data …

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