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A 75-year-old woman with multifocal jejunal strictures
  1. Hui Yann Lee1,
  2. Gina Howarth2,
  3. Robert Willert1
  1. 1Department of Endoscopy, Manchester Royal Infirmary, Central Manchester University Hospitals Foundation Trust, Manchester, UK
  2. 2Department of Histopathology, Manchester Royal Infirmary, Central Manchester University Hospitals Foundation Trust, Manchester, UK
  1. Correspondence to Dr Hui Yann Lee, Department of Endoscopy, Manchester Royal Infirmary, Central Manchester University Hospitals Foundation Trust, Oxford Road, Manchester M13 9WL, UK; huiyann.lee{at}cmft.nhs.uk

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Clinical presentation

A previously fit and well 75-year-old Caucasian woman presented with a 2-month history of postprandial abdominal pain, vomiting and 10 kg weight loss without diarrhoea.

Blood investigations showed marked hypoalbuminaemia of 18 g/L and elevated C reactive protein (CRP) of 185 mg/L. Tissue transglutaminase IgA level was within normal limits without evidence of IgA deficiency. Faecal calprotectin was elevated at 205 µg/g.

Abdominal CT revealed subacute small bowel obstruction characterised by multiple long, thick walled, dilated loops of jejunum (figure 1) associated with lymphadenopathy. Histological findings from laparoscopic mesenteric lymph node resection showed reactive features only.

Figure 1

Coronal CT view of …

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