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The premature invocation of a ‘gut-lung axis’ may obscure the direct effects of respiratory microbiota on pneumonia susceptibility
  1. Robert P Dickson1,
  2. Michael J Cox2
  1. 1Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan, USA
  2. 2National Heart and Lung Institute, Imperial College London, London, UK
  1. Correspondence to Dr Robert P Dickson, Division of Pulmonary and Critical Care Medicine, University of Michigan, 6220 MSRB III/SPC 5642, 1150 W. Medical Center Dr, Ann Arbor, MI 48109-5642, USA; rodickso{at}

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Dear Editor,

We read with interest the work by Schuijt et al1 reporting that sustained treatment with broad-spectrum antibiotics increases the susceptibility of mice to pneumococcal pneumonia, an effect that is reversed via faecal microbiota transplantation (FMT). Yet we question the authors' confidence that this effect is entirely attributable to alterations in …

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