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Response to: ‘Full-spectrum (FUSE) versus standard forward-viewing colonoscopy in an organised colorectal cancer screening programme’ by Hassan et al
  1. Benjamin Nulsen1,
  2. Blair Lewis2,3
  1. 1Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA
  2. 2Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
  3. 3Carnegie Hill Endoscopy, New York, New York, USA
  1. Correspondence to Dr Benjamin Nulsen, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1118, New York, NY 10029-6574, USA; Benjamin.Nulsen{at}mssm.edu

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We read with great interest the recently published study by Hassan et al,1 in which the authors randomised 658 faecal immunochemical test-positive patients in Italy to full-spectrum endoscopy (Fuse) or standard forward-viewing endoscopy (SFV). The authors did not identify a difference between Fuse and SFV in several endpoints, including adenoma detection rate (ADR), advanced adenoma detection rate (A-ADR) and mean number of adenomas and proximal adenomas per colonoscopy. These results were surprising given the significantly lower adenoma miss rate (AMR) with Fuse as compared with SFV (7% vs41%) in a previous multicenter, …

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