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May 1998 (Volume 42, 5). [Index by author]

	(Expand the cover)	LEADING ARTICLES COMMENTARIES SCIENCE ALERTS HELICOBACTER PYLORI SMALL INTESTINE INFLAMMATION AND INFLAMMATORY BOWEL DISEASE CANCER MOTILITY AND VISCERAL SENSATION ENDOSCOPY LIVER CASE REPORTS LETTERS TO THE EDITOR

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LEADING ARTICLES

The relationship between autoimmune markers and different clinical syndromes in autoimmune hepatitis
I G McFARLANE
Gut 1998; 42: 599-602. doi:10.1136/gut.42.5.599 [Extract] [Full text] [PDF] [Request Permissions]

COMMENTARIES

Just how inflamed is the normal gut?
C O'FARRELLY
Gut 1998; 42: 603-604. doi:10.1136/gut.42.5.603 [Extract] [Full text] [PDF] [Request Permissions]

Intestinal metaplasia and the squamocolumnar junction: what does it all mean?
J E RICHTER
Gut 1998; 42: 604-606. doi:10.1136/gut.42.5.604 [Extract] [Full text] [Request Permissions]

Shock news for the gut
T D WARNER and S A McCARTNEY
Gut 1998; 42: 606. doi:10.1136/gut.42.5.606 [Extract] [Full text] [Request Permissions]

SCIENCE ALERTS

Altering cytokine soups: a recipe for inflammatory bowel disease?
J L VINEY
Gut 1998; 42: 607-608. doi:10.1136/gut.42.5.607 [Extract] [Full text] [PDF] [Request Permissions]

HELICOBACTER PYLORI

Chemokines in the gastric mucosa in Helicobacter pylori infection
Y Yamaoka, M Kita, T Kodama, N Sawai, T Tanahashi, K Kashima, and J Imanishi
Gut 1998; 42: 609-617. doi:10.1136/gut.42.5.609 [Abstract] [Full text] [PDF] [Request Permissions]

Assessment of symptomatic response as predictor of Helicobacter pylori status following eradication therapy in patients with ulcer
K E L McColl, A El-Nujumi, L S Murray, E M El-Omar, A Dickson, A W Kelman, and T E Hilditch
Gut 1998; 42: 618-622. doi:10.1136/gut.42.5.618 [Abstract] [Full text] [PDF] [Request Permissions]

SMALL INTESTINE

Nitroxide radical attenuates ischaemia/reperfusion injury to the rat small intestine
R Udassin, Y Haskel, and A Samuni
Gut 1998; 42: 623-627. doi:10.1136/gut.42.5.623 [Abstract] [Full text] [PDF] [Request Permissions]

Medium term effects of a new 5HT₃ antagonist, alosetron, in patients with carcinoid diarrhoea
S B Saslow, J S Scolapio, M Camilleri, L A Forstrom, G M Thomforde, D D Burton, J Rubin, H C Pitot, and A R Zinsmeister
Gut 1998; 42: 628-634. doi:10.1136/gut.42.5.628 [Abstract] [Full text] [PDF] [Request Permissions]

INFLAMMATION AND INFLAMMATORY BOWEL DISEASE

Cytokine profiles of cultured microvascular endothelial cells from the human intestine
E M Nilsen, F-E Johansen, F L Jahnsen, K E A Lundin, T Scholz, P Brandtzaeg, and G Haraldsen
Gut 1998; 42: 635-642. doi:10.1136/gut.42.5.635 [Abstract] [Full text] [PDF] [Request Permissions]

Spontaneous secretion of interferon $gamma$ and interleukin 4 by human intraepithelial and lamina propria gut lymphocytes
M Carol, A Lambrechts, A Van Gossum, M Libin, M Goldman, and F Mascart-Lemone
Gut 1998; 42: 643-649. doi:10.1136/gut.42.5.643 [Abstract] [Full text] [PDF] [Request Permissions]

Tumour necrosis factor- $alpha$ enhances intraepithelial lymphocyte proliferation and migration
E C Ebert
Gut 1998; 42: 650-655. doi:10.1136/gut.42.5.650 [Abstract] [Full text] [PDF] [Request Permissions]

Effects of smoking on the urine excretion of oral ⁵¹Cr EDTA in ulcerative colitis
C Benoni and H Prytz
Gut 1998; 42: 656-658. doi:10.1136/gut.42.5.656 [Abstract] [Full text] [PDF] [Request Permissions]

CANCER

Short segments of Barrett's epithelium and intestinal metaplasia in normal appearing oesophagogastric junctions: the same or two different entities?
A Dias Pereira, A Suspiro, P Chaves, A Saraiva, L Glória, J C Mendes de Almeida, C N Leitão, J Soares, and F C Mira
Gut 1998; 42: 659-662. doi:10.1136/gut.42.5.659 [Abstract] [Full text] [PDF] [Request Permissions]

Clonal analysis of isolated intestinal metaplastic glands of stomach using X linked polymorphism
S Nomura, M Kaminishi, K Sugiyama, T Oohara, and H Esumi
Gut 1998; 42: 663-668. doi:10.1136/gut.42.5.663 [Abstract] [Full text] [PDF] [Request Permissions]

Somatic mutations, acetylator status, and prognosis in colorectal cancer
J E Hardingham, W J Butler, D Roder, A Dobrovic, R B Dymock, R E Sage, and I C Roberts-Thomson
Gut 1998; 42: 669-672. doi:10.1136/gut.42.5.669 [Abstract] [Full text] [PDF] [Request Permissions]

Morphology of sporadic colorectal cancer with DNA replication errors
J R Jass, K-A Do, L A Simms, H Iino, C Wynter, S P Pillay, J Searle, G Radford-Smith, J Young, and B Leggett
Gut 1998; 42: 673-679. doi:10.1136/gut.42.5.673 [Abstract] [Full text] [PDF] [Request Permissions]

Infrequent K-ras codon 12 mutation in serrated adenomas of human colorectum
Y Ajioka, H Watanabe, J R Jass, Y Yokota, M Kobayashi, and K Nishikura
Gut 1998; 42: 680-684. doi:10.1136/gut.42.5.680 [Abstract] [Full text] [PDF] [Request Permissions]

MOTILITY AND VISCERAL SENSATION

Small bowel transit of a bran meal residue in humans: sieving of solids from liquids and response to feeding
J M Hebden, P E Blackshaw, A C Perkins, M D'Amato, and R C Spiller
Gut 1998; 42: 685-689. doi:10.1136/gut.42.5.685 [Abstract] [Full text] [PDF] [Request Permissions]

Identification of distinct upper and lower gastrointestinal symptom groupings in an urban population
N J Talley, P Boyce, and M Jones
Gut 1998; 42: 690-695. doi:10.1136/gut.42.5.690 [Abstract] [Full text] [PDF] [Request Permissions]

The endothelin receptor antagonist bosentan restores gut oxygen delivery and reverses intestinal mucosal acidosis in porcine endotoxin shock
A Oldner, M Wanecek, M Goiny, E Weitzberg, A Rudehill, K Alving, and A Sollevi
Gut 1998; 42: 696-702. doi:10.1136/gut.42.5.696 [Abstract] [Full text] [PDF] [Request Permissions]

ENDOSCOPY

Management of occluded biliary Wallstents
T C K Tham, D L Carr-Locke, J Vandervoort, R C K Wong, D R Lichtenstein, J Van Dam, F Ruymann, S Chow, J J Bosco, T Qaseem, D Howell, D Pleskow, W Vannerman, and E D Libby
Gut 1998; 42: 703-707. doi:10.1136/gut.42.5.703 [Abstract] [Full text] [PDF] [Request Permissions]

Ductal dilatation and stenting for residual hepatolithiasis: a promising treatment strategy
S-M Sheen-Chen, Y-F Cheng, F-C Chen, F-F Chou, and T-Y Lee
Gut 1998; 42: 708-710. doi:10.1136/gut.42.5.708 [Abstract] [Full text] [PDF] [Request Permissions]

Is colonoscopic surveillance reducing colorectal cancer mortality in ulcerative colitis? A population based case control study
P Karlén, D Kornfeld, O Broström, R Löfberg, P-G Persson, and A Ekbom
Gut 1998; 42: 711-714. doi:10.1136/gut.42.5.711 [Abstract] [Full text] [PDF] [Request Permissions]

LIVER

Evidence for altered hepatic matrix degradation in genetic haemochromatosis
D K George, G A Ramm, L W Powell, L M Fletcher, N I Walker, L L Cowley, and D H G Crawford
Gut 1998; 42: 715-720. doi:10.1136/gut.42.5.715 [Abstract] [Full text] [PDF] [Request Permissions]

Liver/kidney microsomal antibody type 1 and liver cytosol antibody type 1 concentrations in type 2 autoimmune hepatitis
L Muratori, M Cataleta, P Muratori, M Lenzi, and F B Bianchi
Gut 1998; 42: 721-726. doi:10.1136/gut.42.5.721 [Abstract] [Full text] [PDF] [Request Permissions]

The liver in systemic amyloidosis: insights from ¹²³I serum amyloid P component scintigraphy in 484 patients
L B Lovat, M R Persey, S Madhoo, M B Pepys, and P N Hawkins
Gut 1998; 42: 727-734. doi:10.1136/gut.42.5.727 [Abstract] [Full text] [PDF] [Request Permissions]

In vivo and in vitro hepatic phosphorus-31 magnetic resonance spectroscopy and electron microscopy in chronic ductopenic rejection of human liver allografts
S D Taylor-Robinson, J Sargentoni, J D Bell, E L Thomas, C D Marcus, K K Changani, N Saeed, H J F Hodgson, B R Davidson, A K Burroughs, K Rolles, C S Foster, and I J Cox
Gut 1998; 42: 735-743. doi:10.1136/gut.42.5.735 [Abstract] [Full text] [PDF] [Request Permissions]

Outcome of orthotopic liver transplantation in patients with haemophilia
F H Gordon, P K Mistry, C A Sabin, and C A Lee
Gut 1998; 42: 744-749. doi:10.1136/gut.42.5.744 [Abstract] [Full text] [PDF] [Request Permissions]

CASE REPORTS

Tranexamic acid for severe bleeding gastric antral vascular ectasia in cirrhosis
P A McCormick, H Ooi, and O Crosbie
Gut 1998; 42: 750-752. doi:10.1136/gut.42.5.750 [Abstract] [Full text] [PDF] [Request Permissions]

Autoantibodies against subunits of pyruvate dehydrogenase and citrate synthase in a case of paediatric biliary cirrhosis
B Melegh, G Skuta, L Pajor, and B Sumegi
Gut 1998; 42: 753-756. doi:10.1136/gut.42.5.753 [Abstract] [Full text] [PDF] [Request Permissions]

LETTERS TO THE EDITOR

The aging stomach • Reply
M GUSLANDI, M LEE, and M FELDMAN
Gut 1998; 42: 757-760. doi:10.1136/gut.42.5.757 [Extract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori: beware "blind" eradication!
C D ROSEVEARE, D A VAN HEEL, M J P ARTHUR, and R J LAWRANCE
Gut 1998; 42: 757. doi:10.1136/gut.42.5.757a [Extract] [Full text] [Request Permissions]

Are complications of endoscopic sphincterotomy age related? • Reply
M H THOMPSON, G T DEANS, W A BROUGH, P SEDMAN, C M S ROYSTON, D F MARTIN, C K LOEW, and W E G THOMAS
Gut 1998; 42: 757. doi:10.1136/gut.42.5.757b [Extract] [Full text] [Request Permissions]

History of dyspepsia in patients with gastric cancer • Reply
R J F LAHEIJ, J B M J JANSEN, E H VAN DE LISDONK, A L M VERBEEK, Z SUVAKOVIC, and M G BRAMBLE
Gut 1998; 42: 757. doi:10.1136/gut.42.5.757c [Extract] [Full text] [Request Permissions]

The genetics of ulcerative colitis based on one Swede • Reply
J J HARDING, J SATSANGI, and D P JEWELL
Gut 1998; 42: 757. doi:10.1136/gut.42.5.757d [Extract] [Full text] [Request Permissions]

Iron reduction therapy in hepatitis C
Y LURIE, M BEER GABEL, I LAMBORT, T SOUMATZKY, S D H MALNICK, and D D BASS
Gut 1998; 42: 757. doi:10.1136/gut.42.5.e757 [Extract] [Full text] [Request Permissions]

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	The relationship between autoimmune markers and different clinical syndromes in autoimmune hepatitis I G McFARLANE Gut 1998; 42: 599-602. doi:10.1136/gut.42.5.599 [Extract] [Full text] [PDF] [Request Permissions]

	Just how inflamed is the normal gut? C O'FARRELLY Gut 1998; 42: 603-604. doi:10.1136/gut.42.5.603 [Extract] [Full text] [PDF] [Request Permissions]

	Intestinal metaplasia and the squamocolumnar junction: what does it all mean? J E RICHTER Gut 1998; 42: 604-606. doi:10.1136/gut.42.5.604 [Extract] [Full text] [Request Permissions]

	Shock news for the gut T D WARNER and S A McCARTNEY Gut 1998; 42: 606. doi:10.1136/gut.42.5.606 [Extract] [Full text] [Request Permissions]

	Altering cytokine soups: a recipe for inflammatory bowel disease? J L VINEY Gut 1998; 42: 607-608. doi:10.1136/gut.42.5.607 [Extract] [Full text] [PDF] [Request Permissions]

	*Chemokines in the gastric mucosa in Helicobacter pylori* infection** Y Yamaoka, M Kita, T Kodama, N Sawai, T Tanahashi, K Kashima, and J Imanishi Gut 1998; 42: 609-617. doi:10.1136/gut.42.5.609 [Abstract] [Full text] [PDF] [Request Permissions]

	*Assessment of symptomatic response as predictor of Helicobacter pylori* status following eradication therapy in patients with ulcer** K E L McColl, A El-Nujumi, L S Murray, E M El-Omar, A Dickson, A W Kelman, and T E Hilditch Gut 1998; 42: 618-622. doi:10.1136/gut.42.5.618 [Abstract] [Full text] [PDF] [Request Permissions]

	Nitroxide radical attenuates ischaemia/reperfusion injury to the rat small intestine R Udassin, Y Haskel, and A Samuni Gut 1998; 42: 623-627. doi:10.1136/gut.42.5.623 [Abstract] [Full text] [PDF] [Request Permissions]

	Medium term effects of a new 5HT₃ antagonist, alosetron, in patients with carcinoid diarrhoea S B Saslow, J S Scolapio, M Camilleri, L A Forstrom, G M Thomforde, D D Burton, J Rubin, H C Pitot, and A R Zinsmeister Gut 1998; 42: 628-634. doi:10.1136/gut.42.5.628 [Abstract] [Full text] [PDF] [Request Permissions]

	Cytokine profiles of cultured microvascular endothelial cells from the human intestine E M Nilsen, F-E Johansen, F L Jahnsen, K E A Lundin, T Scholz, P Brandtzaeg, and G Haraldsen Gut 1998; 42: 635-642. doi:10.1136/gut.42.5.635 [Abstract] [Full text] [PDF] [Request Permissions]

	Spontaneous secretion of interferon $gamma$ and interleukin 4 by human intraepithelial and lamina propria gut lymphocytes M Carol, A Lambrechts, A Van Gossum, M Libin, M Goldman, and F Mascart-Lemone Gut 1998; 42: 643-649. doi:10.1136/gut.42.5.643 [Abstract] [Full text] [PDF] [Request Permissions]

	Tumour necrosis factor- $alpha$ enhances intraepithelial lymphocyte proliferation and migration E C Ebert Gut 1998; 42: 650-655. doi:10.1136/gut.42.5.650 [Abstract] [Full text] [PDF] [Request Permissions]

	Effects of smoking on the urine excretion of oral ⁵¹Cr EDTA in ulcerative colitis C Benoni and H Prytz Gut 1998; 42: 656-658. doi:10.1136/gut.42.5.656 [Abstract] [Full text] [PDF] [Request Permissions]

	Short segments of Barrett's epithelium and intestinal metaplasia in normal appearing oesophagogastric junctions: the same or two different entities? A Dias Pereira, A Suspiro, P Chaves, A Saraiva, L Glória, J C Mendes de Almeida, C N Leitão, J Soares, and F C Mira Gut 1998; 42: 659-662. doi:10.1136/gut.42.5.659 [Abstract] [Full text] [PDF] [Request Permissions]

	Clonal analysis of isolated intestinal metaplastic glands of stomach using X linked polymorphism S Nomura, M Kaminishi, K Sugiyama, T Oohara, and H Esumi Gut 1998; 42: 663-668. doi:10.1136/gut.42.5.663 [Abstract] [Full text] [PDF] [Request Permissions]

	Somatic mutations, acetylator status, and prognosis in colorectal cancer J E Hardingham, W J Butler, D Roder, A Dobrovic, R B Dymock, R E Sage, and I C Roberts-Thomson Gut 1998; 42: 669-672. doi:10.1136/gut.42.5.669 [Abstract] [Full text] [PDF] [Request Permissions]

	Morphology of sporadic colorectal cancer with DNA replication errors J R Jass, K-A Do, L A Simms, H Iino, C Wynter, S P Pillay, J Searle, G Radford-Smith, J Young, and B Leggett Gut 1998; 42: 673-679. doi:10.1136/gut.42.5.673 [Abstract] [Full text] [PDF] [Request Permissions]

	*Infrequent K-ras* codon 12 mutation in serrated adenomas of human colorectum** Y Ajioka, H Watanabe, J R Jass, Y Yokota, M Kobayashi, and K Nishikura Gut 1998; 42: 680-684. doi:10.1136/gut.42.5.680 [Abstract] [Full text] [PDF] [Request Permissions]

	Small bowel transit of a bran meal residue in humans: sieving of solids from liquids and response to feeding J M Hebden, P E Blackshaw, A C Perkins, M D'Amato, and R C Spiller Gut 1998; 42: 685-689. doi:10.1136/gut.42.5.685 [Abstract] [Full text] [PDF] [Request Permissions]

	Identification of distinct upper and lower gastrointestinal symptom groupings in an urban population N J Talley, P Boyce, and M Jones Gut 1998; 42: 690-695. doi:10.1136/gut.42.5.690 [Abstract] [Full text] [PDF] [Request Permissions]

	The endothelin receptor antagonist bosentan restores gut oxygen delivery and reverses intestinal mucosal acidosis in porcine endotoxin shock A Oldner, M Wanecek, M Goiny, E Weitzberg, A Rudehill, K Alving, and A Sollevi Gut 1998; 42: 696-702. doi:10.1136/gut.42.5.696 [Abstract] [Full text] [PDF] [Request Permissions]

	Management of occluded biliary Wallstents T C K Tham, D L Carr-Locke, J Vandervoort, R C K Wong, D R Lichtenstein, J Van Dam, F Ruymann, S Chow, J J Bosco, T Qaseem, D Howell, D Pleskow, W Vannerman, and E D Libby Gut 1998; 42: 703-707. doi:10.1136/gut.42.5.703 [Abstract] [Full text] [PDF] [Request Permissions]

	Ductal dilatation and stenting for residual hepatolithiasis: a promising treatment strategy S-M Sheen-Chen, Y-F Cheng, F-C Chen, F-F Chou, and T-Y Lee Gut 1998; 42: 708-710. doi:10.1136/gut.42.5.708 [Abstract] [Full text] [PDF] [Request Permissions]

	Is colonoscopic surveillance reducing colorectal cancer mortality in ulcerative colitis? A population based case control study P Karlén, D Kornfeld, O Broström, R Löfberg, P-G Persson, and A Ekbom Gut 1998; 42: 711-714. doi:10.1136/gut.42.5.711 [Abstract] [Full text] [PDF] [Request Permissions]

	Evidence for altered hepatic matrix degradation in genetic haemochromatosis D K George, G A Ramm, L W Powell, L M Fletcher, N I Walker, L L Cowley, and D H G Crawford Gut 1998; 42: 715-720. doi:10.1136/gut.42.5.715 [Abstract] [Full text] [PDF] [Request Permissions]

	Liver/kidney microsomal antibody type 1 and liver cytosol antibody type 1 concentrations in type 2 autoimmune hepatitis L Muratori, M Cataleta, P Muratori, M Lenzi, and F B Bianchi Gut 1998; 42: 721-726. doi:10.1136/gut.42.5.721 [Abstract] [Full text] [PDF] [Request Permissions]

	The liver in systemic amyloidosis: insights from ¹²³I serum amyloid P component scintigraphy in 484 patients L B Lovat, M R Persey, S Madhoo, M B Pepys, and P N Hawkins Gut 1998; 42: 727-734. doi:10.1136/gut.42.5.727 [Abstract] [Full text] [PDF] [Request Permissions]

	In vivo and in vitro hepatic phosphorus-31 magnetic resonance spectroscopy and electron microscopy in chronic ductopenic rejection of human liver allografts S D Taylor-Robinson, J Sargentoni, J D Bell, E L Thomas, C D Marcus, K K Changani, N Saeed, H J F Hodgson, B R Davidson, A K Burroughs, K Rolles, C S Foster, and I J Cox Gut 1998; 42: 735-743. doi:10.1136/gut.42.5.735 [Abstract] [Full text] [PDF] [Request Permissions]

	Outcome of orthotopic liver transplantation in patients with haemophilia F H Gordon, P K Mistry, C A Sabin, and C A Lee Gut 1998; 42: 744-749. doi:10.1136/gut.42.5.744 [Abstract] [Full text] [PDF] [Request Permissions]

	Tranexamic acid for severe bleeding gastric antral vascular ectasia in cirrhosis P A McCormick, H Ooi, and O Crosbie Gut 1998; 42: 750-752. doi:10.1136/gut.42.5.750 [Abstract] [Full text] [PDF] [Request Permissions]

	Autoantibodies against subunits of pyruvate dehydrogenase and citrate synthase in a case of paediatric biliary cirrhosis B Melegh, G Skuta, L Pajor, and B Sumegi Gut 1998; 42: 753-756. doi:10.1136/gut.42.5.753 [Abstract] [Full text] [PDF] [Request Permissions]

	The aging stomach • Reply M GUSLANDI, M LEE, and M FELDMAN Gut 1998; 42: 757-760. doi:10.1136/gut.42.5.757 [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori: beware "blind" eradication! C D ROSEVEARE, D A VAN HEEL, M J P ARTHUR, and R J LAWRANCE Gut 1998; 42: 757. doi:10.1136/gut.42.5.757a [Extract] [Full text] [Request Permissions]

	Are complications of endoscopic sphincterotomy age related? • Reply M H THOMPSON, G T DEANS, W A BROUGH, P SEDMAN, C M S ROYSTON, D F MARTIN, C K LOEW, and W E G THOMAS Gut 1998; 42: 757. doi:10.1136/gut.42.5.757b [Extract] [Full text] [Request Permissions]

	History of dyspepsia in patients with gastric cancer • Reply R J F LAHEIJ, J B M J JANSEN, E H VAN DE LISDONK, A L M VERBEEK, Z SUVAKOVIC, and M G BRAMBLE Gut 1998; 42: 757. doi:10.1136/gut.42.5.757c [Extract] [Full text] [Request Permissions]

	The genetics of ulcerative colitis based on one Swede • Reply J J HARDING, J SATSANGI, and D P JEWELL Gut 1998; 42: 757. doi:10.1136/gut.42.5.757d [Extract] [Full text] [Request Permissions]

	Iron reduction therapy in hepatitis C Y LURIE, M BEER GABEL, I LAMBORT, T SOUMATZKY, S D H MALNICK, and D D BASS Gut 1998; 42: 757. doi:10.1136/gut.42.5.e757 [Extract] [Full text] [Request Permissions]