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August 1998 (Volume 43, 2). [Index by author]

	(Expand the cover)	LEADING ARTICLES COMMENTARIES SCIENCE ALERTS HELICOBACTER PYLORI SMALL INTESTINE INFLAMMATORY BOWEL DISEASE CANCER PANCREAS CELL BIOLOGY MOTILITY AND VISCERAL SENSATION LIVER ENDOSCOPY CASE REPORTS OCCASIONAL REPORTS REVIEWS LETTERS TO THE EDITOR BOOK REVIEWS

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LEADING ARTICLES

Matrix metalloproteinases in gastrointestinal cancer
P D BROWN
Gut 1998; 43: 161-163. doi:10.1136/gut.43.2.161 [Extract] [Full text] [PDF] [Request Permissions]

COMMENTARIES

Coeliac disease: how much of what is toxic to whom?
C F FEIGHERY
Gut 1998; 43: 164-165. doi:10.1136/gut.43.2.164 [Extract] [Full text] [PDF] [Request Permissions]

SCIENCE ALERTS

Recognition by human gut $gamma$ $delta$ cells of stress inducible major histocompatibility molecules on enterocytes
E GRIFFITH, E RAMSBURG, and A HAYDAY
Gut 1998; 43: 166-167. doi:10.1136/gut.43.2.166 [Extract] [Full text] [PDF] [Request Permissions]

HELICOBACTER PYLORI

Systemic and local immune responses against Helicobacter pylori urease in patients with chronic gastritis: distinct IgA and IgG productive sites
S Futagami, H Takahashi, Y Norose, and M Kobayashi
Gut 1998; 43: 168-175. doi:10.1136/gut.43.2.168 [Abstract] [Full text] [PDF] [Request Permissions]

The histamine H₃ receptor agonist N-methylhistamine produced by Helicobacter pylori does not alter somatostatin release from cultured rabbit fundic D-cells
I L P Beales and J Calam
Gut 1998; 43: 176-181. doi:10.1136/gut.43.2.176 [Abstract] [Full text] [PDF] [Request Permissions]

Analysis of Helicobacter pylori vacA and cagA genotypes and serum antibody profile in benign and malignant gastroduodenal diseases
D Basso, F Navaglia, L Brigato, M G Piva, A Toma, E Greco, F Di Mario, F Galeotti, G Roveroni, A Corsini, and M Plebani
Gut 1998; 43: 182-186. doi:10.1136/gut.43.2.182 [Abstract] [Full text] [PDF] [Request Permissions]

SMALL INTESTINE

CTLA-4 gene polymorphism is associated with predisposition to coeliac disease
I Djilali-Saiah, J Schmitz, E Harfouch-Hammoud, J-F Mougenot, J-F Bach, and S Caillat-Zucman
Gut 1998; 43: 187-189. doi:10.1136/gut.43.2.187 [Abstract] [Full text] [PDF] [Request Permissions]

Measurement of gluten using a monoclonal antibody to a coeliac toxic peptide of A gliadin
H J Ellis, S Rosen-Bronson, N O'Reilly, and P J Ciclitira
Gut 1998; 43: 190-195. doi:10.1136/gut.43.2.190 [Abstract] [Full text] [PDF] [Request Permissions]

Bromelain protects piglets from diarrhoea caused by oral challenge with K88 positive enterotoxigenic Escherichia coli
D S Chandler and T L Mynott
Gut 1998; 43: 196-202. doi:10.1136/gut.43.2.196 [Abstract] [Full text] [PDF] [Request Permissions]

INFLAMMATORY BOWEL DISEASE

Secretion imbalance between tumour necrosis factor and its inhibitor in inflammatory bowel disease
M Noguchi, N Hiwatashi, Z Liu, and T Toyota
Gut 1998; 43: 203-209. doi:10.1136/gut.43.2.203 [Abstract] [Full text] [PDF] [Request Permissions]

Analysis of MHC class II DP, DQ and DR alleles in Crohn's disease
A Cariappa, B Sands, D Forcione, D Finkelstein, D K Podolsky, and S Pillai
Gut 1998; 43: 210-215. doi:10.1136/gut.43.2.210 [Abstract] [Full text] [PDF] [Request Permissions]

CANCER

Impact of endoscopic biopsy surveillance of Barrett's oesophagus on pathological stage and clinical outcome of Barrett's carcinoma
J W van Sandick, J J B van Lanschot, B W Kuiken, G N J Tytgat, G J A Offerhaus, and H Obertop
Gut 1998; 43: 216-222. doi:10.1136/gut.43.2.216 [Abstract] [Full text] [PDF] [Request Permissions]

Clinical symptoms, hormone profiles, treatment, and prognosis in patients with gastric carcinoids
D Granberg, E Wilander, M Stridsberg, G Granerus, B Skogseid, and K Öberg
Gut 1998; 43: 223-228. doi:10.1136/gut.43.2.223 [Abstract] [Full text] [PDF] [Request Permissions]

Flat adenomas exist in asymptomatic people: important implications for colorectal cancer screening programmes
A R Hart, S Kudo, E H Mackay, J F Mayberry, and W S Atkin
Gut 1998; 43: 229-231. doi:10.1136/gut.43.2.229 [Abstract] [Full text] [PDF] [Request Permissions]

PANCREAS

A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotising pancreatitis in rabbits
M O Osman, J U Kristensen, N O Jacobsen, S B Lausten, B Deleuran, M Deleuran, B Gesser, K Matsushima, C G Larsen, and S L Jensen
Gut 1998; 43: 232-239. doi:10.1136/gut.43.2.232 [Abstract] [Full text] [PDF] [Request Permissions]

CELL BIOLOGY

Distribution and metabolism of intravenously administered trefoil factor 2/porcine spasmolytic polypeptide in the rat
S S Poulsen, J Thulesen, E Nexø, and L Thim
Gut 1998; 43: 240-247. doi:10.1136/gut.43.2.240 [Abstract] [Full text] [PDF] [Request Permissions]

MOTILITY AND VISCERAL SENSATION

Evidence for a lipid specific effect in nutrient induced human proximal gastric relaxation
J T McLaughlin, L E A Troncon, J Barlow, L J Heggie, and D G Thompson
Gut 1998; 43: 248-251. doi:10.1136/gut.43.2.248 [Abstract] [Full text] [PDF] [Request Permissions]

Intraluminal capsaicin does not affect fluid and electrolyte absorption in the human jejunum but does cause pain
J Hammer, H F Hammer, A J Eherer, W Petritsch, P Holzer, and G J Krejs
Gut 1998; 43: 252-255. doi:10.1136/gut.43.2.252 [Abstract] [Full text] [PDF] [Request Permissions]

Level of chronic life stress predicts clinical outcome in irritable bowel syndrome
E J Bennett, C C Tennant, C Piesse, C-A Badcock, and J E Kellow
Gut 1998; 43: 256-261. doi:10.1136/gut.43.2.256 [Abstract] [Full text] [PDF] [Request Permissions]

LIVER

Heterozygotes for HFE mutations have no increased risk of advanced alcoholic liver disease
J Grove, A K Daly, A D Burt, M Guzail, O F W James, M F Bassendine, and C P Day
Gut 1998; 43: 262-266. doi:10.1136/gut.43.2.262 [Abstract] [Full text] [PDF] [Request Permissions]

Thrombelastographic changes and early rebleeding in cirrhotic patients with variceal bleeding
T N Chau, Y W Chan, D Patch, S Tokunaga, L Greenslade, and A K Burroughs
Gut 1998; 43: 267-271. doi:10.1136/gut.43.2.267 [Abstract] [Full text] [PDF] [Request Permissions]

Hepatosplanchnic haemodynamics and renal blood flow and function in rats with liver failure
P Javlé, J Yates, H G Kynaston, K F Parsons, and S A Jenkins
Gut 1998; 43: 272-279. doi:10.1136/gut.43.2.272 [Abstract] [Full text] [PDF] [Request Permissions]

ENDOSCOPY

Two way push videoenteroscopy in investigation of small bowel disease
Y Bouhnik, A Bitoun, B Coffin, R Moussaoui, A Oudghiri, and J C Rambaud
Gut 1998; 43: 280-284. doi:10.1136/gut.43.2.280 [Abstract] [Full text] [PDF] [Request Permissions]

CASE REPORTS

Ischaemic enterocolitis complicating idiopathic dysautonomia
J M Woodward, D S A Sanders, M R Keighley, and R N Allan
Gut 1998; 43: 285-287. doi:10.1136/gut.43.2.285 [Abstract] [Full text] [PDF] [Request Permissions]

OCCASIONAL REPORTS

Gastroenterology research in the United Kingdom: funding sources and impact
G Lewison
Gut 1998; 43: 288-293. doi:10.1136/gut.43.2.288 [Abstract] [Full text] [PDF] [Request Permissions]

REVIEWS

Salt and water absorption in the human colon: a modern appraisal
G I SANDLE
Gut 1998; 43: 294-299. doi:10.1136/gut.43.2.294 [Extract] [Full text] [PDF] [Request Permissions]

LETTERS TO THE EDITOR

Association between primary biliary cirrhosis and coeliac disease • Primary biliary cirrhosis and coeliac disease: a study of relative prevalences • Reply
W DICKEY, S A MCMILLAN, H M FIDLER, P BUTLER, A K BURROUGHS, N MCINTYRE, C BUNN, M MCMORROW, R WALMSLEY, J DOOLEY, J G C KINGHAM, and D R PARKER
Gut 1998; 43: 300. doi:10.1136/gut.43.2.300 [Extract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori: the African enigma
I SEGAL, R ALLY, F SITAS, and A R P WALKER
Gut 1998; 43: 300. doi:10.1136/gut.43.2.300a [Extract] [Full text] [Request Permissions]

6-Mercaptopurine metabolism in Crohn's disease • Reply
A BALLINGER, Y THÉORÊT, and E G SEIDMAN
Gut 1998; 43: 300. doi:10.1136/gut.43.2.300b [Extract] [Full text] [Request Permissions]

BOOK REVIEWS

Imaging of Abdominal and Pelvic Anatomy
D NOLAN
Gut 1998; 43: 300. doi:10.1136/gut.43.2.300c [Extract] [Full text] [Request Permissions]

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	Matrix metalloproteinases in gastrointestinal cancer P D BROWN Gut 1998; 43: 161-163. doi:10.1136/gut.43.2.161 [Extract] [Full text] [PDF] [Request Permissions]

	Coeliac disease: how much of what is toxic to whom? C F FEIGHERY Gut 1998; 43: 164-165. doi:10.1136/gut.43.2.164 [Extract] [Full text] [PDF] [Request Permissions]

	Recognition by human gut $gamma$ $delta$ cells of stress inducible major histocompatibility molecules on enterocytes E GRIFFITH, E RAMSBURG, and A HAYDAY Gut 1998; 43: 166-167. doi:10.1136/gut.43.2.166 [Extract] [Full text] [PDF] [Request Permissions]

	*Systemic and local immune responses against Helicobacter pylori* urease in patients with chronic gastritis: distinct IgA and IgG productive sites** S Futagami, H Takahashi, Y Norose, and M Kobayashi Gut 1998; 43: 168-175. doi:10.1136/gut.43.2.168 [Abstract] [Full text] [PDF] [Request Permissions]

	*The histamine H₃ receptor agonist N-methylhistamine produced by Helicobacter pylori* does not alter somatostatin release from cultured rabbit fundic D-cells** I L P Beales and J Calam Gut 1998; 43: 176-181. doi:10.1136/gut.43.2.176 [Abstract] [Full text] [PDF] [Request Permissions]

	*Analysis of Helicobacter pylori vacA* and cagA genotypes and serum antibody profile in benign and malignant gastroduodenal diseases** D Basso, F Navaglia, L Brigato, M G Piva, A Toma, E Greco, F Di Mario, F Galeotti, G Roveroni, A Corsini, and M Plebani Gut 1998; 43: 182-186. doi:10.1136/gut.43.2.182 [Abstract] [Full text] [PDF] [Request Permissions]

	CTLA-4 gene polymorphism is associated with predisposition to coeliac disease I Djilali-Saiah, J Schmitz, E Harfouch-Hammoud, J-F Mougenot, J-F Bach, and S Caillat-Zucman Gut 1998; 43: 187-189. doi:10.1136/gut.43.2.187 [Abstract] [Full text] [PDF] [Request Permissions]

	Measurement of gluten using a monoclonal antibody to a coeliac toxic peptide of A gliadin H J Ellis, S Rosen-Bronson, N O'Reilly, and P J Ciclitira Gut 1998; 43: 190-195. doi:10.1136/gut.43.2.190 [Abstract] [Full text] [PDF] [Request Permissions]

	Bromelain protects piglets from diarrhoea caused by oral challenge with K88 positive enterotoxigenic Escherichia coli D S Chandler and T L Mynott Gut 1998; 43: 196-202. doi:10.1136/gut.43.2.196 [Abstract] [Full text] [PDF] [Request Permissions]

	Secretion imbalance between tumour necrosis factor and its inhibitor in inflammatory bowel disease M Noguchi, N Hiwatashi, Z Liu, and T Toyota Gut 1998; 43: 203-209. doi:10.1136/gut.43.2.203 [Abstract] [Full text] [PDF] [Request Permissions]

	Analysis of MHC class II DP, DQ and DR alleles in Crohn's disease A Cariappa, B Sands, D Forcione, D Finkelstein, D K Podolsky, and S Pillai Gut 1998; 43: 210-215. doi:10.1136/gut.43.2.210 [Abstract] [Full text] [PDF] [Request Permissions]

	Impact of endoscopic biopsy surveillance of Barrett's oesophagus on pathological stage and clinical outcome of Barrett's carcinoma J W van Sandick, J J B van Lanschot, B W Kuiken, G N J Tytgat, G J A Offerhaus, and H Obertop Gut 1998; 43: 216-222. doi:10.1136/gut.43.2.216 [Abstract] [Full text] [PDF] [Request Permissions]

	Clinical symptoms, hormone profiles, treatment, and prognosis in patients with gastric carcinoids D Granberg, E Wilander, M Stridsberg, G Granerus, B Skogseid, and K Öberg Gut 1998; 43: 223-228. doi:10.1136/gut.43.2.223 [Abstract] [Full text] [PDF] [Request Permissions]

	Flat adenomas exist in asymptomatic people: important implications for colorectal cancer screening programmes A R Hart, S Kudo, E H Mackay, J F Mayberry, and W S Atkin Gut 1998; 43: 229-231. doi:10.1136/gut.43.2.229 [Abstract] [Full text] [PDF] [Request Permissions]

	A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotising pancreatitis in rabbits M O Osman, J U Kristensen, N O Jacobsen, S B Lausten, B Deleuran, M Deleuran, B Gesser, K Matsushima, C G Larsen, and S L Jensen Gut 1998; 43: 232-239. doi:10.1136/gut.43.2.232 [Abstract] [Full text] [PDF] [Request Permissions]

	Distribution and metabolism of intravenously administered trefoil factor 2/porcine spasmolytic polypeptide in the rat S S Poulsen, J Thulesen, E Nexø, and L Thim Gut 1998; 43: 240-247. doi:10.1136/gut.43.2.240 [Abstract] [Full text] [PDF] [Request Permissions]

	Evidence for a lipid specific effect in nutrient induced human proximal gastric relaxation J T McLaughlin, L E A Troncon, J Barlow, L J Heggie, and D G Thompson Gut 1998; 43: 248-251. doi:10.1136/gut.43.2.248 [Abstract] [Full text] [PDF] [Request Permissions]

	Intraluminal capsaicin does not affect fluid and electrolyte absorption in the human jejunum but does cause pain J Hammer, H F Hammer, A J Eherer, W Petritsch, P Holzer, and G J Krejs Gut 1998; 43: 252-255. doi:10.1136/gut.43.2.252 [Abstract] [Full text] [PDF] [Request Permissions]

	Level of chronic life stress predicts clinical outcome in irritable bowel syndrome E J Bennett, C C Tennant, C Piesse, C-A Badcock, and J E Kellow Gut 1998; 43: 256-261. doi:10.1136/gut.43.2.256 [Abstract] [Full text] [PDF] [Request Permissions]

	*Heterozygotes for HFE* mutations have no increased risk of advanced alcoholic liver disease** J Grove, A K Daly, A D Burt, M Guzail, O F W James, M F Bassendine, and C P Day Gut 1998; 43: 262-266. doi:10.1136/gut.43.2.262 [Abstract] [Full text] [PDF] [Request Permissions]

	Thrombelastographic changes and early rebleeding in cirrhotic patients with variceal bleeding T N Chau, Y W Chan, D Patch, S Tokunaga, L Greenslade, and A K Burroughs Gut 1998; 43: 267-271. doi:10.1136/gut.43.2.267 [Abstract] [Full text] [PDF] [Request Permissions]

	Hepatosplanchnic haemodynamics and renal blood flow and function in rats with liver failure P Javlé, J Yates, H G Kynaston, K F Parsons, and S A Jenkins Gut 1998; 43: 272-279. doi:10.1136/gut.43.2.272 [Abstract] [Full text] [PDF] [Request Permissions]

	Two way push videoenteroscopy in investigation of small bowel disease Y Bouhnik, A Bitoun, B Coffin, R Moussaoui, A Oudghiri, and J C Rambaud Gut 1998; 43: 280-284. doi:10.1136/gut.43.2.280 [Abstract] [Full text] [PDF] [Request Permissions]

	Ischaemic enterocolitis complicating idiopathic dysautonomia J M Woodward, D S A Sanders, M R Keighley, and R N Allan Gut 1998; 43: 285-287. doi:10.1136/gut.43.2.285 [Abstract] [Full text] [PDF] [Request Permissions]

	Gastroenterology research in the United Kingdom: funding sources and impact G Lewison Gut 1998; 43: 288-293. doi:10.1136/gut.43.2.288 [Abstract] [Full text] [PDF] [Request Permissions]

	Salt and water absorption in the human colon: a modern appraisal G I SANDLE Gut 1998; 43: 294-299. doi:10.1136/gut.43.2.294 [Extract] [Full text] [PDF] [Request Permissions]

	Association between primary biliary cirrhosis and coeliac disease • Primary biliary cirrhosis and coeliac disease: a study of relative prevalences • Reply W DICKEY, S A MCMILLAN, H M FIDLER, P BUTLER, A K BURROUGHS, N MCINTYRE, C BUNN, M MCMORROW, R WALMSLEY, J DOOLEY, J G C KINGHAM, and D R PARKER Gut 1998; 43: 300. doi:10.1136/gut.43.2.300 [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori: the African enigma I SEGAL, R ALLY, F SITAS, and A R P WALKER Gut 1998; 43: 300. doi:10.1136/gut.43.2.300a [Extract] [Full text] [Request Permissions]

	6-Mercaptopurine metabolism in Crohn's disease • Reply A BALLINGER, Y THÉORÊT, and E G SEIDMAN Gut 1998; 43: 300. doi:10.1136/gut.43.2.300b [Extract] [Full text] [Request Permissions]

	Imaging of Abdominal and Pelvic Anatomy D NOLAN Gut 1998; 43: 300. doi:10.1136/gut.43.2.300c [Extract] [Full text] [Request Permissions]