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April 1999 (Volume 44, 4). [Index by author]

	(Expand the cover)	LEADING ARTICLES COMMENTARIES SCIENCE ALERTS CLINICAL ALERTS HELICOBACTER PYLORI MOTILITY SMALL INTESTINE COLON INFLAMMATORY BOWEL DISEASE QUALITY OF LIFE PANCREATIC DISEASE BILE AND GALLSTONES LIVER DISEASE REVIEWS LETTERS TO THE EDITOR BOOK REVIEWS

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LEADING ARTICLES

What keeps hepatocytes on the straight and narrow? Maintaining differentiated function in the liver
C SELDEN, M KHALIL, and H J F HODGSON
Gut 1999; 44: 443-446. doi:10.1136/gut.44.4.443 [Extract] [Full text] [PDF] [Request Permissions]

COMMENTARIES

Helicobacter pylori resists arrest
R J OWEN
Gut 1999; 44: 447-448. doi:10.1136/gut.44.4.447 [Extract] [Full text] [PDF] [Request Permissions]

Omeprazole: Helicobacter pylori makes thee greater yet
D PANTOFLICKOVA, A L BLUM, and P BERCIK
Gut 1999; 44: 448-449. doi:10.1136/gut.44.4.448 [Extract] [Full text] [Request Permissions]

The hiatus hernia slides back into prominence
J DENT
Gut 1999; 44: 449-450. doi:10.1136/gut.44.4.449 [Extract] [Full text] [Request Permissions]

The quality of quality of life
E J IRVINE
Gut 1999; 44: 450-451. doi:10.1136/gut.44.4.450 [Extract] [Full text] [Request Permissions]

New kids on the block: pancreatic stellate cells enter the fibrogenesis world
M PINZANI
Gut 1999; 44: 451-452. doi:10.1136/gut.44.4.451 [Extract] [Full text] [Request Permissions]

Budd-Chiari syndrome: blocked veins, open mind
D PATCH and A BURROUGHS
Gut 1999; 44: 452-453. doi:10.1136/gut.44.4.452 [Extract] [Full text] [Request Permissions]

SCIENCE ALERTS

Proteolytic release of membrane bound intercellular regulators
V E EYSSELEIN;
Gut 1999; 44: 454. doi:10.1136/gut.44.4.454 [Extract] [Full text] [PDF] [Request Permissions]

CLINICAL ALERTS

Balsalazide led to greater remission rates and tolerance than mesalamine in acute ulcerative colitis • Commentary
S B HANAUER
Gut 1999; 44: 455. doi:10.1136/gut.44.4.455 [Extract] [Full text] [PDF] [Request Permissions]

HELICOBACTER PYLORI

Role of apoptosis induced by Helicobacter pylori infection in the development of duodenal ulcer
K Kohda, K Tanaka, Y Aiba, M Yasuda, T Miwa, and Y Koga
Gut 1999; 44: 456-462. doi:10.1136/gut.44.4.456 [Abstract] [Full text] [PDF] [Request Permissions]

Direct detection of Helicobacter pylori resistance to macrolides by a polymerase chain reaction/DNA enzyme immunoassay in gastric biopsy specimens
A Marais, L Monteiro, A Occhialini, M Pina, H Lamouliatte, and F Mégraud
Gut 1999; 44: 463-467. doi:10.1136/gut.44.4.463 [Abstract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori infection potentiates the inhibition of gastric acid secretion by omeprazole
D Gillen, A A Wirz, W D Neithercut, J E S Ardill, and K E L McColl
Gut 1999; 44: 468-475. doi:10.1136/gut.44.4.468 [Abstract] [Full text] [PDF] [Request Permissions]

MOTILITY

The effect of hiatus hernia on gastro-oesophageal junction pressure
P J Kahrilas, S Lin, J Chen, and M Manka
Gut 1999; 44: 476-482. doi:10.1136/gut.44.4.476 [Abstract] [Full text] [PDF] [Request Permissions]

SMALL INTESTINE

Geography of intestinal permeability and absorption
I S Menzies, M J Zuckerman, W S Nukajam, S G Somasundaram, B Murphy, A P Jenkins, R S Crane, and G G Gregory
Gut 1999; 44: 483-489. doi:10.1136/gut.44.4.483 [Abstract] [Full text] [PDF] [Request Permissions]

Acute increase, stimulated by prostaglandin E₂, in glucose absorption via the sodium dependent glucose transporter-1 in rat intestine
B Scholtka, F Stümpel, and K Jungermann
Gut 1999; 44: 490-496. doi:10.1136/gut.44.4.490 [Abstract] [Full text] [PDF] [Request Permissions]

Involvement of tachykinin receptors in sensitisation to cow's milk proteins in guinea pigs
J Gay, J Fioramonti, R Garcia-Villar, X Emonds-Alt, and L Bueno
Gut 1999; 44: 497-503. doi:10.1136/gut.44.4.497 [Abstract] [Full text] [PDF] [Request Permissions]

COLON

Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro
M Riegler, M Lotz, C Sears, C Pothoulakis, I Castagliuolo, C C Wang, R Sedivy, T Sogukoglu, E Cosentini, G Bischof, W Feil, B Teleky, G Hamilton, J T LaMont, and E Wenzl
Gut 1999; 44: 504-510. doi:10.1136/gut.44.4.504 [Abstract] [Full text] [PDF] [Request Permissions]

Clinical spectral characterisation of colonic mucosal lesions using autofluorescence and $delta$ aminolevulinic acid sensitisation
C Eker, S Montán, E Jaramillo, K Koizumi, C Rubio, S Andersson-Engels, K Svanberg, S Svanberg, and P Slezak
Gut 1999; 44: 511-518. doi:10.1136/gut.44.4.511 [Abstract] [Full text] [PDF] [Request Permissions]

INFLAMMATORY BOWEL DISEASE

Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses
H Yang, S E Plevy, K Taylor, D Tyan, N Fischel-Ghodsian, C McElree, S R Targan, and J I Rotter
Gut 1999; 44: 519-526. doi:10.1136/gut.44.4.519 [Abstract] [Full text] [PDF] [Request Permissions]

QUALITY OF LIFE

Validation of a specific quality of life questionnaire for functional digestive disorders
O Chassany, P Marquis, B Scherrer, N W Read, T Finger, J F Bergmann, B Fraitag, J Geneve, and C Caulin
Gut 1999; 44: 527-533. doi:10.1136/gut.44.4.527 [Abstract] [Full text] [PDF] [Request Permissions]

PANCREATIC DISEASE

Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis
M V Apte, P S Haber, S J Darby, S C Rodgers, G W McCaughan, M A Korsten, R C Pirola, and J S Wilson
Gut 1999; 44: 534-541. doi:10.1136/gut.44.4.534 [Abstract] [Full text] [PDF] [Request Permissions]

Underestimation of acute pancreatitis: patients with only a small increase in amylase/lipase levels can also have or develop severe acute pancreatitis
P G Lankisch, S Burchard-Reckert, and D Lehnick
Gut 1999; 44: 542-544. doi:10.1136/gut.44.4.542 [Abstract] [Full text] [PDF] [Request Permissions]

Immunoreactive pancreatic Reg protein in sera from cystic fibrosis patients with and without pancreatic insufficiency
J Carrère, O Guy-Crotte, E Gaia, and C Figarella
Gut 1999; 44: 545-551. doi:10.1136/gut.44.4.545 [Abstract] [Full text] [PDF] [Request Permissions]

BILE AND GALLSTONES

Effect of long term simvastatin administration as an adjunct to ursodeoxycholic acid: evidence for a synergistic effect on biliary bile acid composition but not on serum lipids in humans
F Lanzarotto, B Panarotto, R Sorbara, M Panteghini, F Pagani, S Sosta, and A Lanzini
Gut 1999; 44: 552-556. doi:10.1136/gut.44.4.552 [Abstract] [Full text] [PDF] [Request Permissions]

The role of apolipoprotein E and glucose intolerance in gallstone disease in middle aged subjects
M Niemi, K Kervinen, A Rantala, H Kauma, M Päivänsalo, M J Savolainen, M Lilja, and Y A Kesäniemi
Gut 1999; 44: 557-562. doi:10.1136/gut.44.4.557 [Abstract] [Full text] [PDF] [Request Permissions]

LIVER DISEASE

The natural course of hepatitis C virus infection 18 years after an epidemic outbreak of non-A, non-B hepatitis in a plasmapheresis centre
C Datz, M Cramp, T Haas, O Dietze, H Nitschko, G Froesner, N Muss, F Sandhofer, and W Vogel
Gut 1999; 44: 563-567. doi:10.1136/gut.44.4.563 [Abstract] [Full text] [PDF] [Request Permissions]

Managing Budd-Chiari syndrome: a retrospective review of percutaneous hepatic vein angioplasty and surgical shunting
N C Fisher, I McCafferty, M Dolapci, M Wali, J A C Buckels, S P Olliff, and E Elias
Gut 1999; 44: 568-574. doi:10.1136/gut.44.4.568 [Abstract] [Full text] [PDF] [Request Permissions]

REVIEWS

Hepatitis C virus recurrence after liver transplantation
T BIZOLLON, C DUCERF, C TREPO, and D MUTIMER
Gut 1999; 44: 575-578. doi:10.1136/gut.44.4.575 [Abstract] [Full text] [PDF] [Request Permissions]

LETTERS TO THE EDITOR

"Non-alcoholic duct destructive chronic pancreatitis" or "primary chronic pancreatitis"?
L FRULLONI, P BOVO, V DI FRANCESCO, G CAVALLINI, and G ZAMBONI
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579 [Extract] [Full text] [PDF] [Request Permissions]

Guidelines for treatment of acute pancreatitis
A ANDRIULLI, F PERRI, V ANNESE, and G LEANDRO
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579a [Extract] [Full text] [Request Permissions]

Colonoscopic surveillance in ulcerative colitis
G GARAS
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579b [Extract] [Full text] [Request Permissions]

Cholecystokinin provocation tests
A W MAJEED and A G JOHNSON
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579c [Extract] [Full text] [Request Permissions]

Requiem for the cholecystokinin provocation test • Reply
W R MURRAY and A W MAJEED
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579d [Extract] [Full text] [Request Permissions]

Cholecystokinin infusion and gall bladder dysfunction
G W MIDDLETON and J H WILLIAMS
Gut 1999; 44: 579. doi:10.1136/gut.44.4.e579 [Extract] [Full text] [Request Permissions]

Ductal dilatation and stenting for residual hepatolithiasis
J E J KRIGE, I J BECKINGHAM, J TERBLANCHE, and S J BENINGFIELD
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579f [Extract] [Full text] [Request Permissions]

The Helicobacter pylori breath test: a surrogate marker for peptic ulcer disease in dyspeptic patients • Reply
C M PATHAK, K L KHANDUJA, D K BHASIN, B C SHARMA, T E HILDITCH, and K E L McCOLL
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579g [Extract] [Full text] [Request Permissions]

BOOK REVIEWS

The Esophagogastric Junction
A J P M SMOUT
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579h [Extract] [Full text] [Request Permissions]

Pancreatic Cancer Pathogenesis Diagnosis and Treatment
J SLAVIN
Gut 1999; 44: i579. doi:10.1136/gut.44.4.i579 [Extract] [Full text] [Request Permissions]

Imaging of Small Intestinal Tumours
C BARTRAM
Gut 1999; 44: 579. doi:10.1136/gut.44.4.579j [Extract] [Full text] [Request Permissions]

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	What keeps hepatocytes on the straight and narrow? Maintaining differentiated function in the liver C SELDEN, M KHALIL, and H J F HODGSON Gut 1999; 44: 443-446. doi:10.1136/gut.44.4.443 [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori resists arrest R J OWEN Gut 1999; 44: 447-448. doi:10.1136/gut.44.4.447 [Extract] [Full text] [PDF] [Request Permissions]

	*Omeprazole: Helicobacter pylori* makes thee greater yet** D PANTOFLICKOVA, A L BLUM, and P BERCIK Gut 1999; 44: 448-449. doi:10.1136/gut.44.4.448 [Extract] [Full text] [Request Permissions]

	The hiatus hernia slides back into prominence J DENT Gut 1999; 44: 449-450. doi:10.1136/gut.44.4.449 [Extract] [Full text] [Request Permissions]

	The quality of quality of life E J IRVINE Gut 1999; 44: 450-451. doi:10.1136/gut.44.4.450 [Extract] [Full text] [Request Permissions]

	New kids on the block: pancreatic stellate cells enter the fibrogenesis world M PINZANI Gut 1999; 44: 451-452. doi:10.1136/gut.44.4.451 [Extract] [Full text] [Request Permissions]

	Budd-Chiari syndrome: blocked veins, open mind D PATCH and A BURROUGHS Gut 1999; 44: 452-453. doi:10.1136/gut.44.4.452 [Extract] [Full text] [Request Permissions]

	Proteolytic release of membrane bound intercellular regulators V E EYSSELEIN; Gut 1999; 44: 454. doi:10.1136/gut.44.4.454 [Extract] [Full text] [PDF] [Request Permissions]

	Balsalazide led to greater remission rates and tolerance than mesalamine in acute ulcerative colitis • Commentary S B HANAUER Gut 1999; 44: 455. doi:10.1136/gut.44.4.455 [Extract] [Full text] [PDF] [Request Permissions]

	*Role of apoptosis induced by Helicobacter pylori* infection in the development of duodenal ulcer** K Kohda, K Tanaka, Y Aiba, M Yasuda, T Miwa, and Y Koga Gut 1999; 44: 456-462. doi:10.1136/gut.44.4.456 [Abstract] [Full text] [PDF] [Request Permissions]

	*Direct detection of Helicobacter pylori* resistance to macrolides by a polymerase chain reaction/DNA enzyme immunoassay in gastric biopsy specimens** A Marais, L Monteiro, A Occhialini, M Pina, H Lamouliatte, and F Mégraud Gut 1999; 44: 463-467. doi:10.1136/gut.44.4.463 [Abstract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori infection potentiates the inhibition of gastric acid secretion by omeprazole D Gillen, A A Wirz, W D Neithercut, J E S Ardill, and K E L McColl Gut 1999; 44: 468-475. doi:10.1136/gut.44.4.468 [Abstract] [Full text] [PDF] [Request Permissions]

	The effect of hiatus hernia on gastro-oesophageal junction pressure P J Kahrilas, S Lin, J Chen, and M Manka Gut 1999; 44: 476-482. doi:10.1136/gut.44.4.476 [Abstract] [Full text] [PDF] [Request Permissions]

	Geography of intestinal permeability and absorption I S Menzies, M J Zuckerman, W S Nukajam, S G Somasundaram, B Murphy, A P Jenkins, R S Crane, and G G Gregory Gut 1999; 44: 483-489. doi:10.1136/gut.44.4.483 [Abstract] [Full text] [PDF] [Request Permissions]

	Acute increase, stimulated by prostaglandin E₂, in glucose absorption via the sodium dependent glucose transporter-1 in rat intestine B Scholtka, F Stümpel, and K Jungermann Gut 1999; 44: 490-496. doi:10.1136/gut.44.4.490 [Abstract] [Full text] [PDF] [Request Permissions]

	Involvement of tachykinin receptors in sensitisation to cow's milk proteins in guinea pigs J Gay, J Fioramonti, R Garcia-Villar, X Emonds-Alt, and L Bueno Gut 1999; 44: 497-503. doi:10.1136/gut.44.4.497 [Abstract] [Full text] [PDF] [Request Permissions]

	Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro M Riegler, M Lotz, C Sears, C Pothoulakis, I Castagliuolo, C C Wang, R Sedivy, T Sogukoglu, E Cosentini, G Bischof, W Feil, B Teleky, G Hamilton, J T LaMont, and E Wenzl Gut 1999; 44: 504-510. doi:10.1136/gut.44.4.504 [Abstract] [Full text] [PDF] [Request Permissions]

	Clinical spectral characterisation of colonic mucosal lesions using autofluorescence and $delta$ aminolevulinic acid sensitisation C Eker, S Montán, E Jaramillo, K Koizumi, C Rubio, S Andersson-Engels, K Svanberg, S Svanberg, and P Slezak Gut 1999; 44: 511-518. doi:10.1136/gut.44.4.511 [Abstract] [Full text] [PDF] [Request Permissions]

	Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses H Yang, S E Plevy, K Taylor, D Tyan, N Fischel-Ghodsian, C McElree, S R Targan, and J I Rotter Gut 1999; 44: 519-526. doi:10.1136/gut.44.4.519 [Abstract] [Full text] [PDF] [Request Permissions]

	Validation of a specific quality of life questionnaire for functional digestive disorders O Chassany, P Marquis, B Scherrer, N W Read, T Finger, J F Bergmann, B Fraitag, J Geneve, and C Caulin Gut 1999; 44: 527-533. doi:10.1136/gut.44.4.527 [Abstract] [Full text] [PDF] [Request Permissions]

	Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis M V Apte, P S Haber, S J Darby, S C Rodgers, G W McCaughan, M A Korsten, R C Pirola, and J S Wilson Gut 1999; 44: 534-541. doi:10.1136/gut.44.4.534 [Abstract] [Full text] [PDF] [Request Permissions]

	Underestimation of acute pancreatitis: patients with only a small increase in amylase/lipase levels can also have or develop severe acute pancreatitis P G Lankisch, S Burchard-Reckert, and D Lehnick Gut 1999; 44: 542-544. doi:10.1136/gut.44.4.542 [Abstract] [Full text] [PDF] [Request Permissions]

	Immunoreactive pancreatic Reg protein in sera from cystic fibrosis patients with and without pancreatic insufficiency J Carrère, O Guy-Crotte, E Gaia, and C Figarella Gut 1999; 44: 545-551. doi:10.1136/gut.44.4.545 [Abstract] [Full text] [PDF] [Request Permissions]

	Effect of long term simvastatin administration as an adjunct to ursodeoxycholic acid: evidence for a synergistic effect on biliary bile acid composition but not on serum lipids in humans F Lanzarotto, B Panarotto, R Sorbara, M Panteghini, F Pagani, S Sosta, and A Lanzini Gut 1999; 44: 552-556. doi:10.1136/gut.44.4.552 [Abstract] [Full text] [PDF] [Request Permissions]

	The role of apolipoprotein E and glucose intolerance in gallstone disease in middle aged subjects M Niemi, K Kervinen, A Rantala, H Kauma, M Päivänsalo, M J Savolainen, M Lilja, and Y A Kesäniemi Gut 1999; 44: 557-562. doi:10.1136/gut.44.4.557 [Abstract] [Full text] [PDF] [Request Permissions]

	The natural course of hepatitis C virus infection 18 years after an epidemic outbreak of non-A, non-B hepatitis in a plasmapheresis centre C Datz, M Cramp, T Haas, O Dietze, H Nitschko, G Froesner, N Muss, F Sandhofer, and W Vogel Gut 1999; 44: 563-567. doi:10.1136/gut.44.4.563 [Abstract] [Full text] [PDF] [Request Permissions]

	Managing Budd-Chiari syndrome: a retrospective review of percutaneous hepatic vein angioplasty and surgical shunting N C Fisher, I McCafferty, M Dolapci, M Wali, J A C Buckels, S P Olliff, and E Elias Gut 1999; 44: 568-574. doi:10.1136/gut.44.4.568 [Abstract] [Full text] [PDF] [Request Permissions]

	Hepatitis C virus recurrence after liver transplantation T BIZOLLON, C DUCERF, C TREPO, and D MUTIMER Gut 1999; 44: 575-578. doi:10.1136/gut.44.4.575 [Abstract] [Full text] [PDF] [Request Permissions]

	"Non-alcoholic duct destructive chronic pancreatitis" or "primary chronic pancreatitis"? L FRULLONI, P BOVO, V DI FRANCESCO, G CAVALLINI, and G ZAMBONI Gut 1999; 44: 579. doi:10.1136/gut.44.4.579 [Extract] [Full text] [PDF] [Request Permissions]

	Guidelines for treatment of acute pancreatitis A ANDRIULLI, F PERRI, V ANNESE, and G LEANDRO Gut 1999; 44: 579. doi:10.1136/gut.44.4.579a [Extract] [Full text] [Request Permissions]

	Colonoscopic surveillance in ulcerative colitis G GARAS Gut 1999; 44: 579. doi:10.1136/gut.44.4.579b [Extract] [Full text] [Request Permissions]

	Cholecystokinin provocation tests A W MAJEED and A G JOHNSON Gut 1999; 44: 579. doi:10.1136/gut.44.4.579c [Extract] [Full text] [Request Permissions]

	Requiem for the cholecystokinin provocation test • Reply W R MURRAY and A W MAJEED Gut 1999; 44: 579. doi:10.1136/gut.44.4.579d [Extract] [Full text] [Request Permissions]

	Cholecystokinin infusion and gall bladder dysfunction G W MIDDLETON and J H WILLIAMS Gut 1999; 44: 579. doi:10.1136/gut.44.4.e579 [Extract] [Full text] [Request Permissions]

	Ductal dilatation and stenting for residual hepatolithiasis J E J KRIGE, I J BECKINGHAM, J TERBLANCHE, and S J BENINGFIELD Gut 1999; 44: 579. doi:10.1136/gut.44.4.579f [Extract] [Full text] [Request Permissions]

	*The Helicobacter pylori* breath test: a surrogate marker for peptic ulcer disease in dyspeptic patients • Reply** C M PATHAK, K L KHANDUJA, D K BHASIN, B C SHARMA, T E HILDITCH, and K E L McCOLL Gut 1999; 44: 579. doi:10.1136/gut.44.4.579g [Extract] [Full text] [Request Permissions]

	The Esophagogastric Junction A J P M SMOUT Gut 1999; 44: 579. doi:10.1136/gut.44.4.579h [Extract] [Full text] [Request Permissions]

	Pancreatic Cancer Pathogenesis Diagnosis and Treatment J SLAVIN Gut 1999; 44: i579. doi:10.1136/gut.44.4.i579 [Extract] [Full text] [Request Permissions]

	Imaging of Small Intestinal Tumours C BARTRAM Gut 1999; 44: 579. doi:10.1136/gut.44.4.579j [Extract] [Full text] [Request Permissions]