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August 1999 (Volume 45, 2). [Index by author]

	(Expand the cover)	LEADING ARTICLES COMMENTARIES SCIENCE ALERTS OESOPHAGUS AND STOMACH INFLAMMATION AND INFLAMMATORY BOWEL DISEASE SMALL INTESTINE NEOPLASIA HISTOPATHOLOGY MOTILITY PANCREAS LIVER DISEASE CASE REPORTS GUT FILE REVIEWS

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LEADING ARTICLES

Hepatitis C and liver transplantation
M BERENGUER and T L WRIGHT
Gut 1999; 45: 159-163. doi:10.1136/gut.45.2.159 [Extract] [Full text] [PDF] [Request Permissions]

COMMENTARIES

Helicobacter pylori and dyspepsia: trick or treat?
ROGER JONES
Gut 1999; 45: 164-165. doi:10.1136/gut.45.2.164 [Extract] [Full text] [PDF] [Request Permissions]

The pill: safe sex and Crohn's disease?
E M ALSTEAD
Gut 1999; 45: 165-166. doi:10.1136/gut.45.2.165 [Extract] [Full text] [Request Permissions]

Gall bladder and bowel: the links multiply
K W HEATON
Gut 1999; 45: 166-167. doi:10.1136/gut.45.2.166 [Extract] [Full text] [Request Permissions]

Cyclosporin and chronic pancreatitis: a supermodel?
M L STEER
Gut 1999; 45: 167-168. doi:10.1136/gut.45.2.167 [Extract] [Full text] [Request Permissions]

HBV + HCV = HCC?
M E CRAMP
Gut 1999; 45: 168-169. doi:10.1136/gut.45.2.168 [Extract] [Full text] [Request Permissions]

SCIENCE ALERTS

Nuclear factor $kappa$ B in liver disease
N J GALLAGHER and L S YOUNG
Gut 1999; 45: 170-171. doi:10.1136/gut.45.2.170 [Extract] [Full text] [PDF] [Request Permissions]

OESOPHAGUS AND STOMACH

Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification
L R Lundell, J Dent, J R Bennett, A L Blum, D Armstrong, J P Galmiche, F Johnson, M Hongo, J E Richter, S J Spechler, G N J Tytgat, and L Wallin
Gut 1999; 45: 172-180. doi:10.1136/gut.45.2.172 [Abstract] [Full text] [PDF] [Request Permissions]

Corpus gastritis is protective against reflux oesophagitis
H B El-Serag, A Sonnenberg, M M Jamal, J M Inadomi, L A Crooks, and R M Feddersen
Gut 1999; 45: 181-185. doi:10.1136/gut.45.2.181 [Abstract] [Full text] [PDF] [Request Permissions]

A prospective randomised trial of a "test and treat" policy versus endoscopy based management in young Helicobacter pylori positive patients with ulcer-like dyspepsia, referred to a hospital clinic
A Heaney, J S A Collins, R G P Watson, R J McFarland, K B Bamford, and T C K Tham
Gut 1999; 45: 186-190. doi:10.1136/gut.45.2.186 [Abstract] [Full text] [PDF] [Request Permissions]

INFLAMMATION AND INFLAMMATORY BOWEL DISEASE

Synergistic effects of interferon $gamma$ and tumour necrosis factor $alpha$ on T84 cell function
S M Fish, R Proujansky, and W W Reenstra
Gut 1999; 45: 191-198. doi:10.1136/gut.45.2.191 [Abstract] [Full text] [PDF] [Request Permissions]

Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase
B Zingarelli, C Szabó, and A L Salzman
Gut 1999; 45: 199-209. doi:10.1136/gut.45.2.199 [Abstract] [Full text] [PDF] [Request Permissions]

Strictures in Crohn's disease are characterised by an accumulation of mast cells colocalised with laminin but not with fibronectin or vitronectin
C M Gelbmann, S Mestermann, V Gross, M Köllinger, J Schölmerich, and W Falk
Gut 1999; 45: 210-217. doi:10.1136/gut.45.2.210 [Abstract] [Full text] [PDF] [Request Permissions]

Oral contraceptive use and the clinical course of Crohn's disease: a prospective cohort study
J Cosnes, F Carbonnel, F Carrat, L Beaugerie, and J-P Gendre
Gut 1999; 45: 218-222. doi:10.1136/gut.45.2.218 [Abstract] [Full text] [PDF] [Request Permissions]

SMALL INTESTINE

Gut origin of sepsis: a prospective study investigating associations between bacterial translocation, gastric microflora, and septic morbidity
J MacFie, C O'Boyle, C J Mitchell, P M Buckley, D Johnstone, and P Sudworth
Gut 1999; 45: 223-228. doi:10.1136/gut.45.2.223 [Abstract] [Full text] [PDF] [Request Permissions]

Intestinal crypt cell apoptosis in murine acute graft versus host disease is mediated by tumour necrosis factor $alpha$ and not by the FasL-Fas interaction: effect of pentoxifylline on the development of mucosal atrophy
E Stüber, A Büschenfeld, A von Freier, T Arendt, and U R Fölsch
Gut 1999; 45: 229-235. doi:10.1136/gut.45.2.229 [Abstract] [Full text] [PDF] [Request Permissions]

Structural, neuronal, and functional adaptive changes in atrophic rat ileum
K M Ekelund and E Ekblad
Gut 1999; 45: 236-245. doi:10.1136/gut.45.2.236 [Abstract] [Full text] [PDF] [Request Permissions]

NEOPLASIA

Interleukin 1 and interleukin 1 $beta$ converting enzyme (caspase 1) expression in the human colonic epithelial barrier. Caspase 1 downregulation in colon cancer
A Jarry, G Vallette, E Cassagnau, A Moreau, C Bou-Hanna, P Lemarre, E Letessier, J-C Le Neel, J-P Galmiche, and C L Laboisse
Gut 1999; 45: 246-251. doi:10.1136/gut.45.2.246 [Abstract] [Full text] [PDF] [Request Permissions]

Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers
Y Adachi, H Yamamoto, F Itoh, Y Hinoda, Y Okada, and K Imai
Gut 1999; 45: 252-258. doi:10.1136/gut.45.2.252 [Abstract] [Full text] [PDF] [Request Permissions]

HISTOPATHOLOGY

Polymerase chain reaction based human leucocyte antigen genotyping for the investigation of suspected gastrointestinal biopsy contamination
A C Bateman, S J Turner, J M Theaker, B F Warren, and W M Howell
Gut 1999; 45: 259-263. doi:10.1136/gut.45.2.259 [Abstract] [Full text] [PDF] [Request Permissions]

MOTILITY

Gall bladder emptying in severe idiopathic constipation
C Penning, H A J Gielkens, J B V M Delemarre, C B H W Lamers, and A A M Masclee
Gut 1999; 45: 264-268. doi:10.1136/gut.45.2.264 [Abstract] [Full text] [PDF] [Request Permissions]

PANCREAS

Myofibroblast proliferation, fibrosis, and defective pancreatic repair induced by cyclosporin in rats
E Vaquero, X Molero, X Tian, A Salas, and J-R Malagelada
Gut 1999; 45: 269-277. doi:10.1136/gut.45.2.269 [Abstract] [Full text] [PDF] [Request Permissions]

LIVER DISEASE

Iron overload in urban Africans in the 1990s
I T Gangaidzo, V M Moyo, T Saungweme, H Khumalo, R M Charakupa, Z A R Gomo, M Loyevsky, R Stearman, T La Vaute, E G Enquist, T A Rouault, and V R Gordeuk
Gut 1999; 45: 278-283. doi:10.1136/gut.45.2.278 [Abstract] [Full text] [PDF] [Request Permissions]

High prevalence of anti-hepatitis B virus serological markers in patients with hepatitis C virus related chronic liver disease in Japan
H Marusawa, Y Osaki, T Kimura, K Ito, Y Yamashita, T Eguchi, M Kudo, Y Yamamoto, H Kojima, H Seno, F Moriyasu, and T Chiba
Gut 1999; 45: 284-288. doi:10.1136/gut.45.2.284 [Abstract] [Full text] [PDF] [Request Permissions]

Familial occurrence of nodular regenerative hyperplasia of the liver: a report on three families
J Dumortier, O Boillot, M Chevallier, F Berger, P Potier, P-J Valette, P Paliard, and J-Y Scoazec
Gut 1999; 45: 289-294. doi:10.1136/gut.45.2.289 [Abstract] [Full text] [PDF] [Request Permissions]

Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease
Z M Younossi, G Guyatt, M Kiwi, N Boparai, and D King
Gut 1999; 45: 295-300. doi:10.1136/gut.45.2.295 [Abstract] [Full text] [PDF] [Request Permissions]

Spur cell anaemia and hepatic iron stores in patients with alcoholic liver disease undergoing orthotopic liver transplantation
A Pascoe, P Kerlin, C Steadman, A Clouston, D Jones, L Powell, E Jazwinska, S Lynch, and R Strong
Gut 1999; 45: 301-305. doi:10.1136/gut.45.2.301 [Abstract] [Full text] [PDF] [Request Permissions]

CASE REPORTS

Selection of hepatitis B surface "escape" mutants during passive immune prophylaxis following liver transplantation: potential impact of genetic changes on polymerase protein function
P L Shields, A Owsianka, W F Carman, E Boxall, S G Hubscher, J Shaw, K O'Donnell, E Elias, and D J Mutimer
Gut 1999; 45: 306-309. doi:10.1136/gut.45.2.306 [Abstract] [Full text] [PDF] [Request Permissions]

GUT FILE

A woman who bled after a decade of dyspnoea
N J ROBERTSON, M E F SMITH, A J SHERWOOD, and S P L TRAVIS
Gut 1999; 45: 310. doi:10.1136/gut.45.2.310 [Extract] [Full text] [PDF] [Request Permissions]

REVIEWS

The role of infection in acute pancreatitis
S W SCHMID, W UHL, H FRIESS, P MALFERTHEINER, and M W BÜCHLER
Gut 1999; 45: 311. doi:10.1136/gut.45.2.311 [Extract] [Full text] [PDF] [Request Permissions]

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	Hepatitis C and liver transplantation M BERENGUER and T L WRIGHT Gut 1999; 45: 159-163. doi:10.1136/gut.45.2.159 [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori and dyspepsia: trick or treat? ROGER JONES Gut 1999; 45: 164-165. doi:10.1136/gut.45.2.164 [Extract] [Full text] [PDF] [Request Permissions]

	The pill: safe sex and Crohn's disease? E M ALSTEAD Gut 1999; 45: 165-166. doi:10.1136/gut.45.2.165 [Extract] [Full text] [Request Permissions]

	Gall bladder and bowel: the links multiply K W HEATON Gut 1999; 45: 166-167. doi:10.1136/gut.45.2.166 [Extract] [Full text] [Request Permissions]

	Cyclosporin and chronic pancreatitis: a supermodel? M L STEER Gut 1999; 45: 167-168. doi:10.1136/gut.45.2.167 [Extract] [Full text] [Request Permissions]

	HBV + HCV = HCC? M E CRAMP Gut 1999; 45: 168-169. doi:10.1136/gut.45.2.168 [Extract] [Full text] [Request Permissions]

	Nuclear factor $kappa$ B in liver disease N J GALLAGHER and L S YOUNG Gut 1999; 45: 170-171. doi:10.1136/gut.45.2.170 [Extract] [Full text] [PDF] [Request Permissions]

	Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification L R Lundell, J Dent, J R Bennett, A L Blum, D Armstrong, J P Galmiche, F Johnson, M Hongo, J E Richter, S J Spechler, G N J Tytgat, and L Wallin Gut 1999; 45: 172-180. doi:10.1136/gut.45.2.172 [Abstract] [Full text] [PDF] [Request Permissions]

	Corpus gastritis is protective against reflux oesophagitis H B El-Serag, A Sonnenberg, M M Jamal, J M Inadomi, L A Crooks, and R M Feddersen Gut 1999; 45: 181-185. doi:10.1136/gut.45.2.181 [Abstract] [Full text] [PDF] [Request Permissions]

	*A prospective randomised trial of a "test and treat" policy versus endoscopy based management in young Helicobacter pylori* positive patients with ulcer-like dyspepsia, referred to a hospital clinic** A Heaney, J S A Collins, R G P Watson, R J McFarland, K B Bamford, and T C K Tham Gut 1999; 45: 186-190. doi:10.1136/gut.45.2.186 [Abstract] [Full text] [PDF] [Request Permissions]

	Synergistic effects of interferon $gamma$ and tumour necrosis factor $alpha$ on T84 cell function S M Fish, R Proujansky, and W W Reenstra Gut 1999; 45: 191-198. doi:10.1136/gut.45.2.191 [Abstract] [Full text] [PDF] [Request Permissions]

	Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase B Zingarelli, C Szabó, and A L Salzman Gut 1999; 45: 199-209. doi:10.1136/gut.45.2.199 [Abstract] [Full text] [PDF] [Request Permissions]

	Strictures in Crohn's disease are characterised by an accumulation of mast cells colocalised with laminin but not with fibronectin or vitronectin C M Gelbmann, S Mestermann, V Gross, M Köllinger, J Schölmerich, and W Falk Gut 1999; 45: 210-217. doi:10.1136/gut.45.2.210 [Abstract] [Full text] [PDF] [Request Permissions]

	Oral contraceptive use and the clinical course of Crohn's disease: a prospective cohort study J Cosnes, F Carbonnel, F Carrat, L Beaugerie, and J-P Gendre Gut 1999; 45: 218-222. doi:10.1136/gut.45.2.218 [Abstract] [Full text] [PDF] [Request Permissions]

	Gut origin of sepsis: a prospective study investigating associations between bacterial translocation, gastric microflora, and septic morbidity J MacFie, C O'Boyle, C J Mitchell, P M Buckley, D Johnstone, and P Sudworth Gut 1999; 45: 223-228. doi:10.1136/gut.45.2.223 [Abstract] [Full text] [PDF] [Request Permissions]

	Intestinal crypt cell apoptosis in murine acute graft versus host disease is mediated by tumour necrosis factor $alpha$ and not by the FasL-Fas interaction: effect of pentoxifylline on the development of mucosal atrophy E Stüber, A Büschenfeld, A von Freier, T Arendt, and U R Fölsch Gut 1999; 45: 229-235. doi:10.1136/gut.45.2.229 [Abstract] [Full text] [PDF] [Request Permissions]

	Structural, neuronal, and functional adaptive changes in atrophic rat ileum K M Ekelund and E Ekblad Gut 1999; 45: 236-245. doi:10.1136/gut.45.2.236 [Abstract] [Full text] [PDF] [Request Permissions]

	Interleukin 1 and interleukin 1 $beta$ converting enzyme (caspase 1) expression in the human colonic epithelial barrier. Caspase 1 downregulation in colon cancer A Jarry, G Vallette, E Cassagnau, A Moreau, C Bou-Hanna, P Lemarre, E Letessier, J-C Le Neel, J-P Galmiche, and C L Laboisse Gut 1999; 45: 246-251. doi:10.1136/gut.45.2.246 [Abstract] [Full text] [PDF] [Request Permissions]

	Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers Y Adachi, H Yamamoto, F Itoh, Y Hinoda, Y Okada, and K Imai Gut 1999; 45: 252-258. doi:10.1136/gut.45.2.252 [Abstract] [Full text] [PDF] [Request Permissions]

	Polymerase chain reaction based human leucocyte antigen genotyping for the investigation of suspected gastrointestinal biopsy contamination A C Bateman, S J Turner, J M Theaker, B F Warren, and W M Howell Gut 1999; 45: 259-263. doi:10.1136/gut.45.2.259 [Abstract] [Full text] [PDF] [Request Permissions]

	Gall bladder emptying in severe idiopathic constipation C Penning, H A J Gielkens, J B V M Delemarre, C B H W Lamers, and A A M Masclee Gut 1999; 45: 264-268. doi:10.1136/gut.45.2.264 [Abstract] [Full text] [PDF] [Request Permissions]

	Myofibroblast proliferation, fibrosis, and defective pancreatic repair induced by cyclosporin in rats E Vaquero, X Molero, X Tian, A Salas, and J-R Malagelada Gut 1999; 45: 269-277. doi:10.1136/gut.45.2.269 [Abstract] [Full text] [PDF] [Request Permissions]

	Iron overload in urban Africans in the 1990s I T Gangaidzo, V M Moyo, T Saungweme, H Khumalo, R M Charakupa, Z A R Gomo, M Loyevsky, R Stearman, T La Vaute, E G Enquist, T A Rouault, and V R Gordeuk Gut 1999; 45: 278-283. doi:10.1136/gut.45.2.278 [Abstract] [Full text] [PDF] [Request Permissions]

	High prevalence of anti-hepatitis B virus serological markers in patients with hepatitis C virus related chronic liver disease in Japan H Marusawa, Y Osaki, T Kimura, K Ito, Y Yamashita, T Eguchi, M Kudo, Y Yamamoto, H Kojima, H Seno, F Moriyasu, and T Chiba Gut 1999; 45: 284-288. doi:10.1136/gut.45.2.284 [Abstract] [Full text] [PDF] [Request Permissions]

	Familial occurrence of nodular regenerative hyperplasia of the liver: a report on three families J Dumortier, O Boillot, M Chevallier, F Berger, P Potier, P-J Valette, P Paliard, and J-Y Scoazec Gut 1999; 45: 289-294. doi:10.1136/gut.45.2.289 [Abstract] [Full text] [PDF] [Request Permissions]

	Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease Z M Younossi, G Guyatt, M Kiwi, N Boparai, and D King Gut 1999; 45: 295-300. doi:10.1136/gut.45.2.295 [Abstract] [Full text] [PDF] [Request Permissions]

	Spur cell anaemia and hepatic iron stores in patients with alcoholic liver disease undergoing orthotopic liver transplantation A Pascoe, P Kerlin, C Steadman, A Clouston, D Jones, L Powell, E Jazwinska, S Lynch, and R Strong Gut 1999; 45: 301-305. doi:10.1136/gut.45.2.301 [Abstract] [Full text] [PDF] [Request Permissions]

	Selection of hepatitis B surface "escape" mutants during passive immune prophylaxis following liver transplantation: potential impact of genetic changes on polymerase protein function P L Shields, A Owsianka, W F Carman, E Boxall, S G Hubscher, J Shaw, K O'Donnell, E Elias, and D J Mutimer Gut 1999; 45: 306-309. doi:10.1136/gut.45.2.306 [Abstract] [Full text] [PDF] [Request Permissions]

	A woman who bled after a decade of dyspnoea N J ROBERTSON, M E F SMITH, A J SHERWOOD, and S P L TRAVIS Gut 1999; 45: 310. doi:10.1136/gut.45.2.310 [Extract] [Full text] [PDF] [Request Permissions]

	The role of infection in acute pancreatitis S W SCHMID, W UHL, H FRIESS, P MALFERTHEINER, and M W BÜCHLER Gut 1999; 45: 311. doi:10.1136/gut.45.2.311 [Extract] [Full text] [PDF] [Request Permissions]