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February 2000 (Volume 46, Number 2). [Index by author]

	(Cover illustration)	EDITORIALS LEADING ARTICLES COMMENTARIES SCIENCE ALERTS STOMACH INFLAMMATORY BOWEL DISEASE CANCER MOTILITY COLON PANCREAS GALL BLADDER LIVER DISEASE CASE REPORTS REVIEWS LETTERS TO THE EDITOR

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EDITORIALS

Gut in 2000
MICHAEL FARTHING
Gut 2000; 46: 143. doi:10.1136/gut.46.2.143 [Extract] [Full text] [PDF] [Request Permissions]

LEADING ARTICLES

Proton pump inhibitors for Barrett's oesophagus
G TRIADAFILOPOULOS
Gut 2000; 46: 144-146. doi:10.1136/gut.46.2.144 [Extract] [Full text] [PDF] [Request Permissions]

Barrett's oesophagus and proton pump inhibitors: a pathological perspective
N A SHEPHERD
Gut 2000; 46: 147-149. doi:10.1136/gut.46.2.147 [Extract] [Full text] [PDF] [Request Permissions]

COMMENTARIES

Haute cuisine and the colon
R C SPILLER
Gut 2000; 46: 150-151. doi:10.1136/gut.46.2.150 [Extract] [Full text] [PDF] [Request Permissions]

DMT1 expression: avoiding too much of a good thing
A P WALKER
Gut 2000; 46: 151-152. doi:10.1136/gut.46.2.151 [Extract] [Full text] [PDF] [Request Permissions]

Fibrosing colonopathy
J A DODGE
Gut 2000; 46: 152-153. doi:10.1136/gut.46.2.152 [Extract] [Full text] [PDF] [Request Permissions]

SCIENCE ALERTS

Prostaglandins and the induction of food sensitive enteropathy
A McI MOWAT
Gut 2000; 46: 154-155. doi:10.1136/gut.46.2.154 [Extract] [Full text] [PDF] [Request Permissions]

STOMACH

Exogenous nitric oxide inhibits apoptosis in guinea pig gastric mucous cells
C L Potter and P J Hanson
Gut 2000; 46: 156-162. doi:10.1136/gut.46.2.156 [Abstract] [Full text] [PDF] [Request Permissions]

INFLAMMATORY BOWEL DISEASE

Immunohistochemical analysis of the distribution of measles related antigen in the intestinal mucosa in inflammatory bowel disease
M Iizuka, M Chiba, M Yukawa, T Nakagomi, T Fukushima, S Watanabe, and O Nakagomi
Gut 2000; 46: 163-169. doi:10.1136/gut.46.2.163 [Abstract] [Full text] [PDF] [Request Permissions]

Role of bile acids and bile acid binding agents in patients with collagenous colitis
K-A Ung, R Gillberg, A Kilander, and H Abrahamsson
Gut 2000; 46: 170-175. doi:10.1136/gut.46.2.170 [Abstract] [Full text] [PDF] [Request Permissions]

Fracture risk is increased in Crohn's disease, but not in ulcerative colitis
P Vestergaard, K Krogh, L Rejnmark, S Laurberg, and L Mosekilde
Gut 2000; 46: 176-181. doi:10.1136/gut.46.2.176 [Abstract] [Full text] [PDF] [Request Permissions]

CANCER

Presence of sorbin in human digestive tract and endocrine digestive tumours
F Abou El Fadil-Nicol, F Berger, M Descroix-Vagne, and D Pansu
Gut 2000; 46: 182-190. doi:10.1136/gut.46.2.182 [Abstract] [Full text] [PDF] [Request Permissions]

Effect of olive oil on early and late events of colon carcinogenesis in rats: modulation of arachidonic acid metabolism and local prostaglandin E₂ synthesis
R Bartolí, F Fernández-Bañares, E Navarro, E Castellà, J Mañé, M Alvarez, C Pastor, E Cabré, and M A Gassull
Gut 2000; 46: 191-199. doi:10.1136/gut.46.2.191 [Abstract] [Full text] [PDF] [Request Permissions]

Replication error phenotype, clinicopathological variables, and patient outcome in Dukes' B stage II (T3,N0,M0) colorectal cancer
B Curran, K Lenehan, H Mulcahy, O Tighe, M A Bennett, E W Kay, D P O'Donoghue, M Leader, and D T Croke
Gut 2000; 46: 200-204. doi:10.1136/gut.46.2.200 [Abstract] [Full text] [PDF] [Request Permissions]

MOTILITY

Effects of fat and carbohydrate meals on colonic motor response
S S C Rao, R Kavelock, J Beaty, K Ackerson, and P Stumbo
Gut 2000; 46: 205-211. doi:10.1136/gut.46.2.205 [Abstract] [Full text] [PDF] [Request Permissions]

Laser Doppler flowmetry as a measure of extrinsic colonic innervation in functional bowel disease
A V Emmanuel and M A Kamm
Gut 2000; 46: 212-217. doi:10.1136/gut.46.2.212 [Abstract] [Full text] [PDF] [Request Permissions]

COLON

Mucin secretion is modulated by luminal factors in the isolated vascularly perfused rat colon
A Barcelo, J Claustre, F Moro, J-A Chayvialle, J-C Cuber, and P Plaisancié
Gut 2000; 46: 218-224. doi:10.1136/gut.46.2.218 [Abstract] [Full text] [PDF] [Request Permissions]

Generation of reactive oxygen species by the faecal matrix
R W Owen, B Spiegelhalder, and H Bartsch
Gut 2000; 46: 225-232. doi:10.1136/gut.46.2.225 [Abstract] [Full text] [PDF] [Request Permissions]

PANCREAS

Role of procalcitonin and granulocyte colony stimulating factor in the early prediction of infected necrosis in severe acute pancreatitis
C A Müller, W Uhl, G Printzen, B Gloor, H Bischofberger, O Tcholakov, and M W Büchler
Gut 2000; 46: 233-238. doi:10.1136/gut.46.2.233 [Abstract] [Full text] [PDF] [Request Permissions]

A prospective audit against national standards of the presentation and management of acute pancreatitis in the South of England
S K C Toh, S Phillips, and C D Johnson
Gut 2000; 46: 239-243. doi:10.1136/gut.46.2.239 [Abstract] [Full text] [PDF] [Request Permissions]

Value of endoscopic ultrasound guided fine needle aspiration biopsy in the diagnosis of solid pancreatic masses
M Voss, P Hammel, G Molas, L Palazzo, A Dancour, D O'Toole, B Terris, C Degott, P Bernades, and P Ruszniewski
Gut 2000; 46: 244-249. doi:10.1136/gut.46.2.244 [Abstract] [Full text] [PDF] [Request Permissions]

GALL BLADDER

Endoscopic ultrasonography for differential diagnosis of polypoid gall bladder lesions: analysis in surgical and follow up series
M Sugiyama, Y Atomi, and T Yamato
Gut 2000; 46: 250-254. doi:10.1136/gut.46.2.250 [Abstract] [Full text] [PDF] [Request Permissions]

LIVER DISEASE

Liver infiltrating T lymphocytes express interferon $gamma$ and inducible nitric oxide synthase in chronic hepatitis C virus infection
S Schweyer, S Mihm, H J Radzun, H Hartmann, and A Fayyazi
Gut 2000; 46: 255-259. doi:10.1136/gut.46.2.255 [Abstract] [Full text] [PDF] [Request Permissions]

Increases in intrahepatic CD68 positive cells, MAC387 positive cells, and proinflammatory cytokines (particularly interleukin 18) in chronic hepatitis C infection
P H McGuinness, D Painter, S Davies, and G W McCaughan
Gut 2000; 46: 260-269. doi:10.1136/gut.46.2.260 [Abstract] [Full text] [PDF] [Request Permissions]

Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload
D Trinder, P S Oates, C Thomas, J Sadleir, and E H Morgan
Gut 2000; 46: 270-276. doi:10.1136/gut.46.2.270 [Abstract] [Full text] [PDF] [Request Permissions]

Liver iron is predictive of death in alcoholic cirrhosis: a multivariate study of 229 consecutive patients with alcoholic and/or hepatitis C virus cirrhosis: a prospective follow up study
N Ganne-Carrié, C Christidis, C Chastang, M Ziol, F Chapel, F Imbert-Bismut, J-C Trinchet, C Guettier, and M Beaugrand
Gut 2000; 46: 277-282. doi:10.1136/gut.46.2.277 [Abstract] [Full text] [PDF] [Request Permissions]

CASE REPORTS

Fibrosing colonopathy in an adult owing to over use of pancreatic enzyme supplements
D S Bansi, A Price, C Russell, and M Sarner
Gut 2000; 46: 283-285. doi:10.1136/gut.46.2.283 [Abstract] [Full text] [PDF] [Request Permissions]

REVIEWS

Peptide gene expression in gastrointestinal mucosal ulceration: ordered sequence or redundancy?
W-M WONG, R J PLAYFORD, and N A WRIGHT
Gut 2000; 46: 286-292. doi:10.1136/gut.46.2.286 [Extract] [Full text] [PDF] [Request Permissions]

LETTERS TO THE EDITOR

Ultrasonographic findings in Crohn's disease • Reply
V ARIENTI, L ZAMBONI, P GIONCHETTI, F RIZZELLO, M CAMPIERI;, and C GASCHE
Gut 2000; 46: 293. doi:10.1136/gut.46.2.293 [Extract] [Full text] [PDF] [Request Permissions]

Association between colon cancer and adenocarcinoma of the oesophagus • Reply
R MARIC, K K CHENG;, J LAGERGREN, and P NYREN
Gut 2000; 46: 293. doi:10.1136/gut.46.2.293a [Extract] [Full text] [PDF] [Request Permissions]

Diversion colitis as a trigger for ulcerative colitis
S L JOWETT and I COBDEN
Gut 2000; 46: 293. doi:10.1136/gut.46.2.293b [Extract] [Full text] [PDF] [Request Permissions]

Quality of life of parents of children on home parenteral nutrition
C WONG, A K AKOBENG, V MILLER, and A G THOMAS
Gut 2000; 46: 293. doi:10.1136/gut.46.2.293c [Extract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori infection and autoimmune pathogenesis of gastric neoplasias
G CAMMAROTA and G GASBARRINI
Gut 2000; 46: 293. doi:10.1136/gut.46.2.293d [Extract] [Full text] [PDF] [Request Permissions]

Cover

Double immunostaining of islets of Langerhans in human pancreas using the fluorescein isothiocyanate labelled goat anti-rabbitIgG for sorbin. (From the paper by Abou El Fadil-Nicol et al,pp 182-190.)

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	Gut in 2000 MICHAEL FARTHING Gut 2000; 46: 143. doi:10.1136/gut.46.2.143 [Extract] [Full text] [PDF] [Request Permissions]

	Proton pump inhibitors for Barrett's oesophagus G TRIADAFILOPOULOS Gut 2000; 46: 144-146. doi:10.1136/gut.46.2.144 [Extract] [Full text] [PDF] [Request Permissions]

	Barrett's oesophagus and proton pump inhibitors: a pathological perspective N A SHEPHERD Gut 2000; 46: 147-149. doi:10.1136/gut.46.2.147 [Extract] [Full text] [PDF] [Request Permissions]

	Haute cuisine and the colon R C SPILLER Gut 2000; 46: 150-151. doi:10.1136/gut.46.2.150 [Extract] [Full text] [PDF] [Request Permissions]

	DMT1 expression: avoiding too much of a good thing A P WALKER Gut 2000; 46: 151-152. doi:10.1136/gut.46.2.151 [Extract] [Full text] [PDF] [Request Permissions]

	Fibrosing colonopathy J A DODGE Gut 2000; 46: 152-153. doi:10.1136/gut.46.2.152 [Extract] [Full text] [PDF] [Request Permissions]

	Prostaglandins and the induction of food sensitive enteropathy A McI MOWAT Gut 2000; 46: 154-155. doi:10.1136/gut.46.2.154 [Extract] [Full text] [PDF] [Request Permissions]

	Exogenous nitric oxide inhibits apoptosis in guinea pig gastric mucous cells C L Potter and P J Hanson Gut 2000; 46: 156-162. doi:10.1136/gut.46.2.156 [Abstract] [Full text] [PDF] [Request Permissions]

	Immunohistochemical analysis of the distribution of measles related antigen in the intestinal mucosa in inflammatory bowel disease M Iizuka, M Chiba, M Yukawa, T Nakagomi, T Fukushima, S Watanabe, and O Nakagomi Gut 2000; 46: 163-169. doi:10.1136/gut.46.2.163 [Abstract] [Full text] [PDF] [Request Permissions]

	Role of bile acids and bile acid binding agents in patients with collagenous colitis K-A Ung, R Gillberg, A Kilander, and H Abrahamsson Gut 2000; 46: 170-175. doi:10.1136/gut.46.2.170 [Abstract] [Full text] [PDF] [Request Permissions]

	Fracture risk is increased in Crohn's disease, but not in ulcerative colitis P Vestergaard, K Krogh, L Rejnmark, S Laurberg, and L Mosekilde Gut 2000; 46: 176-181. doi:10.1136/gut.46.2.176 [Abstract] [Full text] [PDF] [Request Permissions]

	Presence of sorbin in human digestive tract and endocrine digestive tumours F Abou El Fadil-Nicol, F Berger, M Descroix-Vagne, and D Pansu Gut 2000; 46: 182-190. doi:10.1136/gut.46.2.182 [Abstract] [Full text] [PDF] [Request Permissions]

	Effect of olive oil on early and late events of colon carcinogenesis in rats: modulation of arachidonic acid metabolism and local prostaglandin E₂ synthesis R Bartolí, F Fernández-Bañares, E Navarro, E Castellà, J Mañé, M Alvarez, C Pastor, E Cabré, and M A Gassull Gut 2000; 46: 191-199. doi:10.1136/gut.46.2.191 [Abstract] [Full text] [PDF] [Request Permissions]

	Replication error phenotype, clinicopathological variables, and patient outcome in Dukes' B stage II (T3,N0,M0) colorectal cancer B Curran, K Lenehan, H Mulcahy, O Tighe, M A Bennett, E W Kay, D P O'Donoghue, M Leader, and D T Croke Gut 2000; 46: 200-204. doi:10.1136/gut.46.2.200 [Abstract] [Full text] [PDF] [Request Permissions]

	Effects of fat and carbohydrate meals on colonic motor response S S C Rao, R Kavelock, J Beaty, K Ackerson, and P Stumbo Gut 2000; 46: 205-211. doi:10.1136/gut.46.2.205 [Abstract] [Full text] [PDF] [Request Permissions]

	Laser Doppler flowmetry as a measure of extrinsic colonic innervation in functional bowel disease A V Emmanuel and M A Kamm Gut 2000; 46: 212-217. doi:10.1136/gut.46.2.212 [Abstract] [Full text] [PDF] [Request Permissions]

	Mucin secretion is modulated by luminal factors in the isolated vascularly perfused rat colon A Barcelo, J Claustre, F Moro, J-A Chayvialle, J-C Cuber, and P Plaisancié Gut 2000; 46: 218-224. doi:10.1136/gut.46.2.218 [Abstract] [Full text] [PDF] [Request Permissions]

	Generation of reactive oxygen species by the faecal matrix R W Owen, B Spiegelhalder, and H Bartsch Gut 2000; 46: 225-232. doi:10.1136/gut.46.2.225 [Abstract] [Full text] [PDF] [Request Permissions]

	Role of procalcitonin and granulocyte colony stimulating factor in the early prediction of infected necrosis in severe acute pancreatitis C A Müller, W Uhl, G Printzen, B Gloor, H Bischofberger, O Tcholakov, and M W Büchler Gut 2000; 46: 233-238. doi:10.1136/gut.46.2.233 [Abstract] [Full text] [PDF] [Request Permissions]

	A prospective audit against national standards of the presentation and management of acute pancreatitis in the South of England S K C Toh, S Phillips, and C D Johnson Gut 2000; 46: 239-243. doi:10.1136/gut.46.2.239 [Abstract] [Full text] [PDF] [Request Permissions]

	Value of endoscopic ultrasound guided fine needle aspiration biopsy in the diagnosis of solid pancreatic masses M Voss, P Hammel, G Molas, L Palazzo, A Dancour, D O'Toole, B Terris, C Degott, P Bernades, and P Ruszniewski Gut 2000; 46: 244-249. doi:10.1136/gut.46.2.244 [Abstract] [Full text] [PDF] [Request Permissions]

	Endoscopic ultrasonography for differential diagnosis of polypoid gall bladder lesions: analysis in surgical and follow up series M Sugiyama, Y Atomi, and T Yamato Gut 2000; 46: 250-254. doi:10.1136/gut.46.2.250 [Abstract] [Full text] [PDF] [Request Permissions]

	Liver infiltrating T lymphocytes express interferon $gamma$ and inducible nitric oxide synthase in chronic hepatitis C virus infection S Schweyer, S Mihm, H J Radzun, H Hartmann, and A Fayyazi Gut 2000; 46: 255-259. doi:10.1136/gut.46.2.255 [Abstract] [Full text] [PDF] [Request Permissions]

	Increases in intrahepatic CD68 positive cells, MAC387 positive cells, and proinflammatory cytokines (particularly interleukin 18) in chronic hepatitis C infection P H McGuinness, D Painter, S Davies, and G W McCaughan Gut 2000; 46: 260-269. doi:10.1136/gut.46.2.260 [Abstract] [Full text] [PDF] [Request Permissions]

	Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload D Trinder, P S Oates, C Thomas, J Sadleir, and E H Morgan Gut 2000; 46: 270-276. doi:10.1136/gut.46.2.270 [Abstract] [Full text] [PDF] [Request Permissions]

	Liver iron is predictive of death in alcoholic cirrhosis: a multivariate study of 229 consecutive patients with alcoholic and/or hepatitis C virus cirrhosis: a prospective follow up study N Ganne-Carrié, C Christidis, C Chastang, M Ziol, F Chapel, F Imbert-Bismut, J-C Trinchet, C Guettier, and M Beaugrand Gut 2000; 46: 277-282. doi:10.1136/gut.46.2.277 [Abstract] [Full text] [PDF] [Request Permissions]

	Fibrosing colonopathy in an adult owing to over use of pancreatic enzyme supplements D S Bansi, A Price, C Russell, and M Sarner Gut 2000; 46: 283-285. doi:10.1136/gut.46.2.283 [Abstract] [Full text] [PDF] [Request Permissions]

	Peptide gene expression in gastrointestinal mucosal ulceration: ordered sequence or redundancy? W-M WONG, R J PLAYFORD, and N A WRIGHT Gut 2000; 46: 286-292. doi:10.1136/gut.46.2.286 [Extract] [Full text] [PDF] [Request Permissions]

	Ultrasonographic findings in Crohn's disease • Reply V ARIENTI, L ZAMBONI, P GIONCHETTI, F RIZZELLO, M CAMPIERI;, and C GASCHE Gut 2000; 46: 293. doi:10.1136/gut.46.2.293 [Extract] [Full text] [PDF] [Request Permissions]

	Association between colon cancer and adenocarcinoma of the oesophagus • Reply R MARIC, K K CHENG;, J LAGERGREN, and P NYREN Gut 2000; 46: 293. doi:10.1136/gut.46.2.293a [Extract] [Full text] [PDF] [Request Permissions]

	Diversion colitis as a trigger for ulcerative colitis S L JOWETT and I COBDEN Gut 2000; 46: 293. doi:10.1136/gut.46.2.293b [Extract] [Full text] [PDF] [Request Permissions]

	Quality of life of parents of children on home parenteral nutrition C WONG, A K AKOBENG, V MILLER, and A G THOMAS Gut 2000; 46: 293. doi:10.1136/gut.46.2.293c [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori infection and autoimmune pathogenesis of gastric neoplasias G CAMMAROTA and G GASBARRINI Gut 2000; 46: 293. doi:10.1136/gut.46.2.293d [Extract] [Full text] [PDF] [Request Permissions]