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June 2001 (Volume 48, Number 6). [Index by author]

	(Cover illustration)	Leading articles Commentaries Therapy update Debate Science alerts Stomach Proliferation and repair Gastrointestinal cancer Liver disease Case reports Gut file Reviews Letters to the editor Book reviews Corrections

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Leading articles

The importance of interleukin 1 $beta$ in Helicobacter pylori associated disease
E M EL-OMAR
Gut 2001; 48: 743-747. doi:10.1136/gut.48.6.743 [Extract] [Full text] [PDF] [Request Permissions]

Detection of persistent measles virus infection in Crohn's disease: current status of experimental work
S GHOSH, E ARMITAGE, D WILSON, P D MINOR, and M A AFZAL
Gut 2001; 48: 748-752. doi:10.1136/gut.48.6.748 [Extract] [Full text] [PDF] [Request Permissions]

Commentaries

Colonoscopic polypectomy and the incidence of colorectal cancer
S J WINAWER and A G ZAUBER
Gut 2001; 48: 753-754. doi:10.1136/gut.48.6.753 [Extract] [Full text] [PDF] [Request Permissions]

Small fry starting to make waves
M ALISON
Gut 2001; 48: 754-755. doi:10.1136/gut.48.6.754 [Extract] [Full text] [PDF] [Request Permissions]

Iron overload in Montpelier
P C ADAMS
Gut 2001; 48: 755-756. doi:10.1136/gut.48.6.755 [Extract] [Full text] [PDF] [Request Permissions]

Therapy update

Liquid diets for Crohn's disease
M O'Sullivan and C O'Morain
Gut 2001; 48: 757. doi:10.1136/gut.48.6.757 [Extract] [Full text] [PDF] [Request Permissions]

Methotrexate in Crohn's disease
D S Rampton
Gut 2001; 48: 790-791. doi:10.1136/gut.48.6.790 [Extract] [Full text] [PDF] [Request Permissions]

Debate

Antagonist: Should we eradicate Helicobacter pylori in non-ulcer dyspepsia?
D Pantoflickova and A L Blum
Gut 2001; 48: 758-759. doi:10.1136/gut.48.6.758 [Extract] [Full text] [Extra figures & legends] [PDF] [Request Permissions]

Protagonist: Should we eradicate Helicobacter pylori in non-ulcer dyspepsia?
K E L McColl
Gut 2001; 48: 759-761. doi:10.1136/gut.48.6.759 [Extract] [Full text] [PDF] [Request Permissions]

Science alerts

T cell control of the gut IgA response against commensal bacteria
N A BOS, H-Q JIANG, and J J CEBRA
Gut 2001; 48: 762-764. doi:10.1136/gut.48.6.762 [Extract] [Full text] [PDF] [Request Permissions]

Stomach

Effects of Helicobacter pylori infection on gastric acid secretion and serum gastrin levels in Mongolian gerbils
M Takashima, T Furuta, H Hanai, H Sugimura, and E Kaneko
Gut 2001; 48: 765-773. doi:10.1136/gut.48.6.765 [Abstract] [Full text] [PDF] [Request Permissions]

Acid regulates inflammatory response in a rat model of induction of gastric ulcer recurrence by interleukin 1 $beta$
T Watanabe, K Higuchi, K Tominaga, Y Fujiwara, and T Arakawa
Gut 2001; 48: 774-781. doi:10.1136/gut.48.6.774 [Abstract] [Full text] [PDF] [Request Permissions]

Inhibition of carbachol stimulated acid secretion by interleukin 1 $beta$ in rabbit parietal cells requires protein kinase C
I L P Beales and J Calam
Gut 2001; 48: 782-789. doi:10.1136/gut.48.6.782 [Abstract] [Full text] [PDF] [Request Permissions]

Proliferation and repair

Ulcer associated cell lineage glands expressing trefoil peptide genes are induced by chronic ulceration in ileal pouch mucosa
M Pera, J Heppell, R Poulsom, F V Teixeira, and J Williams
Gut 2001; 48: 792-796. doi:10.1136/gut.48.6.792 [Abstract] [Full text] [PDF] [Request Permissions]

Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells
H M Roche, A M Terres, I B Black, M J Gibney, and D Kelleher
Gut 2001; 48: 797-802. doi:10.1136/gut.48.6.797 [Abstract] [Full text] [PDF] [Request Permissions]

Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats
J Berlanga-Acosta, R J Playford, N Mandir, and R A Goodlad
Gut 2001; 48: 803-807. doi:10.1136/gut.48.6.803 [Abstract] [Full text] [PDF] [Request Permissions]

Gastrointestinal cancer

Soluble E-cadherin is a valid prognostic marker in gastric carcinoma
A O O Chan, S K Lam, K M Chu, C M Lam, E Kwok, S Y Leung, S T Yuen, S Y K Law, W M Hui, K C Lai, C Y Wong, H C Hu, C L Lai, and J Wong
Gut 2001; 48: 808-811. doi:10.1136/gut.48.6.808 [Abstract] [Full text] [PDF] [Request Permissions]

Efficacy in standard clinical practice of colonoscopic polypectomy in reducing colorectal cancer incidence
F Citarda, G Tomaselli, R Capocaccia, S Barcherini, M Crespi, and The Italian Multicentre Study Group
Gut 2001; 48: 812-815. doi:10.1136/gut.48.6.812 [Abstract] [Full text] [PDF] [Request Permissions]

Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998
S D Taylor-Robinson, M B Toledano, S Arora, T J Keegan, S Hargreaves, A Beck, S A Khan, P Elliott, and H C Thomas
Gut 2001; 48: 816-820. doi:10.1136/gut.48.6.816 [Abstract] [Full text] [PDF] [Request Permissions]

Microsatellite instability and the clinicopathological features of sporadic colorectal cancer
R Ward, A Meagher, I Tomlinson, T O'Connor, M Norrie, R Wu, and N Hawkins
Gut 2001; 48: 821-829. doi:10.1136/gut.48.6.821 [Abstract] [Full text] [PDF] [Request Permissions]

Liver disease

Sequences in the NS5A protein of hepatitis C virus and the serum alanine aminotransferase response to interferon therapy in Japanese patients
K Nagayama, N Enomoto, N Izumi, M Kurosaki, Y Miyasaka, H Watanabe, J Itakura, C-H Chen, J Tazawa, Y Hoshino, T Ikeda, F Marumo, and C Sato
Gut 2001; 48: 830-835. doi:10.1136/gut.48.6.830 [Abstract] [Full text] [PDF] [Request Permissions]

Variable phenotypic presentation of iron overload in H63D homozygotes: are genetic modifiers the cause?
P Aguilar-Martinez, M Bismuth, M C Picot, C Thelcide, G-P Pageaux, F Blanc, P Blanc, J-F Schved, and D Larrey
Gut 2001; 48: 836-842. doi:10.1136/gut.48.6.836 [Abstract] [Full text] [PDF] [Request Permissions]

Impact of interferon therapy on the natural history of hepatitis C virus related cirrhosis
A Gramenzi, P Andreone, S Fiorino, C Cammà, M Giunta, D Magalotti, C Cursaro, C Calabrese, V Arienti, C Rossi, G Di Febo, M Zoli, A Craxì, G Gasbarrini, and M Bernardi
Gut 2001; 48: 843-848. doi:10.1136/gut.48.6.843 [Abstract] [Full text] [PDF] [Request Permissions]

Wilson's disease with severe hepatic insufficiency: beneficial effects of early administration of D-penicillamine
F Durand, J Bernuau, E Giostra, G Mentha, D Shouval, C Degott, J P Benhamou, and D Valla
Gut 2001; 48: 849-852. doi:10.1136/gut.48.6.849 [Abstract] [Full text] [PDF] [Request Permissions]

Case reports

Concurrent occurrence of gastric adenocarcinoma and duodenal neuroendocrine cell carcinoma: a composite tumour or collision tumours ?
H Fukui, M Takada, T Chiba, R Kashiwagi, M Sakane, F Tabata, Y Kuroda, Y Ueda, H Kawamata, J Imura, and T Fujimori
Gut 2001; 48: 853-856. doi:10.1136/gut.48.6.853 [Abstract] [Full text] [PDF] [Request Permissions]

Gut file

A case of hypomagnesaemia due to malabsorption, unresponsive to oral administration of magnesium glycerophosphate, but responsive to oral magnesium oxide supplementation
J R ROSS, P I DARGAN, A L JONES, and A KOSTRZEWSKI
Gut 2001; 48: 857-858. doi:10.1136/gut.48.6.857 [Extract] [Full text] [PDF] [Request Permissions]

Reviews

Cannabinoids and the gastrointestinal tract
R G PERTWEE
Gut 2001; 48: 859-867. doi:10.1136/gut.48.6.859 [Abstract] [Full text] [PDF] [Request Permissions]

Letters to the editor

Survival for colorectal cancer • Reply
S S CROSS, G GATTA, and F BERRINO
Gut 2001; 48: 868-869. doi:10.1136/gut.48.6.868 [Extract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori, Lewis antigens, and inflammation
M A HENEGHAN and A P MORAN
Gut 2001; 48: 869. doi:10.1136/gut.48.6.869 [Extract] [Full text] [PDF] [Request Permissions]

Relation of H pylori to gastric mucins and gastric surface mucous gel layer • Reply
H OTA, J NAKAYAMA, T SHIMIZU, J NAKAYAMA, D Y GRAHAM, T KATSUYAMA, and J DEKKER
Gut 2001; 48: 869-871. doi:10.1136/gut.48.6.869a [Extract] [Full text] [PDF] [Request Permissions]

Helicobacter pylori infection and acid secretion in patients with duodenal ulcer in Japan
T CHIBA, T WATANABE, and T ITO
Gut 2001; 48: 871-872. doi:10.1136/gut.48.6.871 [Extract] [Full text] [PDF] [Request Permissions]

Book reviews

Colon Microbiota, Nutrition and Health
I SEGAL
Gut 2001; 48: 872. doi:10.1136/gut.48.6.872 [Extract] [Full text] [PDF] [Request Permissions]

Advances in Inflammatory Bowel Diseases (Falk Symposium 106)
F SHANAHAN
Gut 2001; 48: 872. doi:10.1136/gut.48.6.872a [Extract] [Full text] [PDF] [Request Permissions]

Corrections

Correction for vol. 47, p. 72
Gut 2001; 48: 872. doi:10.1136/gut.48.6.872b [Extract] [Full text] [PDF] [Request Permissions]

Retraction for vol. 48, p. 20
Gut 2001; 48: 872. doi:10.1136/gut.48.6.872c [Extract] [Full text] [PDF] [Request Permissions]

Cover

Antioccludin immunofluorescent staining of Caco-2 cell monolayers grown in media supplemented with trans-10 conjugated linoleicacid for 21 days. (From the paper by Roche et al, pp 797-802.)

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	*The importance of interleukin 1 $beta$ in Helicobacter pylori* associated disease** E M EL-OMAR Gut 2001; 48: 743-747. doi:10.1136/gut.48.6.743 [Extract] [Full text] [PDF] [Request Permissions]

	Detection of persistent measles virus infection in Crohn's disease: current status of experimental work S GHOSH, E ARMITAGE, D WILSON, P D MINOR, and M A AFZAL Gut 2001; 48: 748-752. doi:10.1136/gut.48.6.748 [Extract] [Full text] [PDF] [Request Permissions]

	Colonoscopic polypectomy and the incidence of colorectal cancer S J WINAWER and A G ZAUBER Gut 2001; 48: 753-754. doi:10.1136/gut.48.6.753 [Extract] [Full text] [PDF] [Request Permissions]

	Small fry starting to make waves M ALISON Gut 2001; 48: 754-755. doi:10.1136/gut.48.6.754 [Extract] [Full text] [PDF] [Request Permissions]

	Iron overload in Montpelier P C ADAMS Gut 2001; 48: 755-756. doi:10.1136/gut.48.6.755 [Extract] [Full text] [PDF] [Request Permissions]

	Liquid diets for Crohn's disease M O'Sullivan and C O'Morain Gut 2001; 48: 757. doi:10.1136/gut.48.6.757 [Extract] [Full text] [PDF] [Request Permissions]

	Methotrexate in Crohn's disease D S Rampton Gut 2001; 48: 790-791. doi:10.1136/gut.48.6.790 [Extract] [Full text] [PDF] [Request Permissions]

	*Antagonist: Should we eradicate Helicobacter pylori* in non-ulcer dyspepsia?** D Pantoflickova and A L Blum Gut 2001; 48: 758-759. doi:10.1136/gut.48.6.758 [Extract] [Full text] [Extra figures & legends] [PDF] [Request Permissions]

	*Protagonist: Should we eradicate Helicobacter pylori* in non-ulcer dyspepsia?** K E L McColl Gut 2001; 48: 759-761. doi:10.1136/gut.48.6.759 [Extract] [Full text] [PDF] [Request Permissions]

	T cell control of the gut IgA response against commensal bacteria N A BOS, H-Q JIANG, and J J CEBRA Gut 2001; 48: 762-764. doi:10.1136/gut.48.6.762 [Extract] [Full text] [PDF] [Request Permissions]

	*Effects of Helicobacter pylori* infection on gastric acid secretion and serum gastrin levels in Mongolian gerbils** M Takashima, T Furuta, H Hanai, H Sugimura, and E Kaneko Gut 2001; 48: 765-773. doi:10.1136/gut.48.6.765 [Abstract] [Full text] [PDF] [Request Permissions]

	Acid regulates inflammatory response in a rat model of induction of gastric ulcer recurrence by interleukin 1 $beta$ T Watanabe, K Higuchi, K Tominaga, Y Fujiwara, and T Arakawa Gut 2001; 48: 774-781. doi:10.1136/gut.48.6.774 [Abstract] [Full text] [PDF] [Request Permissions]

	Inhibition of carbachol stimulated acid secretion by interleukin 1 $beta$ in rabbit parietal cells requires protein kinase C I L P Beales and J Calam Gut 2001; 48: 782-789. doi:10.1136/gut.48.6.782 [Abstract] [Full text] [PDF] [Request Permissions]

	Ulcer associated cell lineage glands expressing trefoil peptide genes are induced by chronic ulceration in ileal pouch mucosa M Pera, J Heppell, R Poulsom, F V Teixeira, and J Williams Gut 2001; 48: 792-796. doi:10.1136/gut.48.6.792 [Abstract] [Full text] [PDF] [Request Permissions]

	Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells H M Roche, A M Terres, I B Black, M J Gibney, and D Kelleher Gut 2001; 48: 797-802. doi:10.1136/gut.48.6.797 [Abstract] [Full text] [PDF] [Request Permissions]

	Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats J Berlanga-Acosta, R J Playford, N Mandir, and R A Goodlad Gut 2001; 48: 803-807. doi:10.1136/gut.48.6.803 [Abstract] [Full text] [PDF] [Request Permissions]

	Soluble E-cadherin is a valid prognostic marker in gastric carcinoma A O O Chan, S K Lam, K M Chu, C M Lam, E Kwok, S Y Leung, S T Yuen, S Y K Law, W M Hui, K C Lai, C Y Wong, H C Hu, C L Lai, and J Wong Gut 2001; 48: 808-811. doi:10.1136/gut.48.6.808 [Abstract] [Full text] [PDF] [Request Permissions]

	Efficacy in standard clinical practice of colonoscopic polypectomy in reducing colorectal cancer incidence F Citarda, G Tomaselli, R Capocaccia, S Barcherini, M Crespi, and The Italian Multicentre Study Group Gut 2001; 48: 812-815. doi:10.1136/gut.48.6.812 [Abstract] [Full text] [PDF] [Request Permissions]

	Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998 S D Taylor-Robinson, M B Toledano, S Arora, T J Keegan, S Hargreaves, A Beck, S A Khan, P Elliott, and H C Thomas Gut 2001; 48: 816-820. doi:10.1136/gut.48.6.816 [Abstract] [Full text] [PDF] [Request Permissions]

	Microsatellite instability and the clinicopathological features of sporadic colorectal cancer R Ward, A Meagher, I Tomlinson, T O'Connor, M Norrie, R Wu, and N Hawkins Gut 2001; 48: 821-829. doi:10.1136/gut.48.6.821 [Abstract] [Full text] [PDF] [Request Permissions]

	Sequences in the NS5A protein of hepatitis C virus and the serum alanine aminotransferase response to interferon therapy in Japanese patients K Nagayama, N Enomoto, N Izumi, M Kurosaki, Y Miyasaka, H Watanabe, J Itakura, C-H Chen, J Tazawa, Y Hoshino, T Ikeda, F Marumo, and C Sato Gut 2001; 48: 830-835. doi:10.1136/gut.48.6.830 [Abstract] [Full text] [PDF] [Request Permissions]

	Variable phenotypic presentation of iron overload in H63D homozygotes: are genetic modifiers the cause? P Aguilar-Martinez, M Bismuth, M C Picot, C Thelcide, G-P Pageaux, F Blanc, P Blanc, J-F Schved, and D Larrey Gut 2001; 48: 836-842. doi:10.1136/gut.48.6.836 [Abstract] [Full text] [PDF] [Request Permissions]

	Impact of interferon therapy on the natural history of hepatitis C virus related cirrhosis A Gramenzi, P Andreone, S Fiorino, C Cammà, M Giunta, D Magalotti, C Cursaro, C Calabrese, V Arienti, C Rossi, G Di Febo, M Zoli, A Craxì, G Gasbarrini, and M Bernardi Gut 2001; 48: 843-848. doi:10.1136/gut.48.6.843 [Abstract] [Full text] [PDF] [Request Permissions]

	Wilson's disease with severe hepatic insufficiency: beneficial effects of early administration of D-penicillamine F Durand, J Bernuau, E Giostra, G Mentha, D Shouval, C Degott, J P Benhamou, and D Valla Gut 2001; 48: 849-852. doi:10.1136/gut.48.6.849 [Abstract] [Full text] [PDF] [Request Permissions]

	Concurrent occurrence of gastric adenocarcinoma and duodenal neuroendocrine cell carcinoma: a composite tumour or collision tumours ? H Fukui, M Takada, T Chiba, R Kashiwagi, M Sakane, F Tabata, Y Kuroda, Y Ueda, H Kawamata, J Imura, and T Fujimori Gut 2001; 48: 853-856. doi:10.1136/gut.48.6.853 [Abstract] [Full text] [PDF] [Request Permissions]

	A case of hypomagnesaemia due to malabsorption, unresponsive to oral administration of magnesium glycerophosphate, but responsive to oral magnesium oxide supplementation J R ROSS, P I DARGAN, A L JONES, and A KOSTRZEWSKI Gut 2001; 48: 857-858. doi:10.1136/gut.48.6.857 [Extract] [Full text] [PDF] [Request Permissions]

	Cannabinoids and the gastrointestinal tract R G PERTWEE Gut 2001; 48: 859-867. doi:10.1136/gut.48.6.859 [Abstract] [Full text] [PDF] [Request Permissions]

	Survival for colorectal cancer • Reply S S CROSS, G GATTA, and F BERRINO Gut 2001; 48: 868-869. doi:10.1136/gut.48.6.868 [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori, Lewis antigens, and inflammation M A HENEGHAN and A P MORAN Gut 2001; 48: 869. doi:10.1136/gut.48.6.869 [Extract] [Full text] [PDF] [Request Permissions]

	*Relation of H pylori* to gastric mucins and gastric surface mucous gel layer • Reply** H OTA, J NAKAYAMA, T SHIMIZU, J NAKAYAMA, D Y GRAHAM, T KATSUYAMA, and J DEKKER Gut 2001; 48: 869-871. doi:10.1136/gut.48.6.869a [Extract] [Full text] [PDF] [Request Permissions]

	Helicobacter pylori infection and acid secretion in patients with duodenal ulcer in Japan T CHIBA, T WATANABE, and T ITO Gut 2001; 48: 871-872. doi:10.1136/gut.48.6.871 [Extract] [Full text] [PDF] [Request Permissions]

	Colon Microbiota, Nutrition and Health I SEGAL Gut 2001; 48: 872. doi:10.1136/gut.48.6.872 [Extract] [Full text] [PDF] [Request Permissions]

	Advances in Inflammatory Bowel Diseases (Falk Symposium 106) F SHANAHAN Gut 2001; 48: 872. doi:10.1136/gut.48.6.872a [Extract] [Full text] [PDF] [Request Permissions]

	Correction for vol. 47, p. 72 Gut 2001; 48: 872. doi:10.1136/gut.48.6.872b [Extract] [Full text] [PDF] [Request Permissions]

	Retraction for vol. 48, p. 20 Gut 2001; 48: 872. doi:10.1136/gut.48.6.872c [Extract] [Full text] [PDF] [Request Permissions]