Leading articles:

Non-pylori helicobacter species in humans

J L O'ROURKE, M GREHAN, and A LEE

Gut 2001; 49: 601-606. doi:10.1136/gut.49.5.601

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Commentaries:

Life, death, and varices

D LEBREC

Gut 2001; 49: 607-608. doi:10.1136/gut.49.5.607

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Can endoscopic papillary balloon dilation really preserve sphincter of Oddi function?

D L CARR-LOCKE

Gut 2001; 49: 608-609. doi:10.1136/gut.49.5.608

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Clinical alerts:

Intravenous omeprazole after endoscopic treatment of bleeding peptic ulcers

K R PALMER

Gut 2001; 49: 610-611. doi:10.1136/gut.49.5.610

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Science alerts:

Genomics at work: the global gene response to enteric bacteria

D KELLY and S CONWAY

Gut 2001; 49: 612-613. doi:10.1136/gut.49.5.612

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Debate:

Protagonist: Should we eradicate Helicobacter pylori before long term antireflux therapy?

J Labenz

Gut 2001; 49: 614-616. doi:10.1136/gut.49.5.614

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Antagonist: Should we eradicate Helicobacter pylori before long term antireflux therapy?

J W Freston

Gut 2001; 49: 616-617. doi:10.1136/gut.49.5.616

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Oesophagus:

Expression of the p53 homologue p63 and Np63 in the neoplastic sequence of Barrett's oesophagus: correlation with morphology and p53 protein

P A Hall, A C Woodman, S J Campbell, and N A Shepherd

Gut 2001; 49: 618-623. doi:10.1136/gut.49.5.618

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Duodenal fat intensifies the perception of heartburn

J H Meyer, A Lembo, J D Elashoff, R Fass, and E A Mayer

Gut 2001; 49: 624-628. doi:10.1136/gut.49.5.624

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Helicobacter pylori:

Analysis of iceA genotypes in South African Helicobacter pylori strains and relationship to clinically significant disease

M Kidd, R M Peek, A J Lastovica, D A Israel, A F Kummer, and J A Louw

Gut 2001; 49: 629-635. doi:10.1136/gut.49.5.629

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Inflammation and inflammatory bowel disease:

Interleukin 2 modulates ion secretion and cell proliferation in cultured human small intestinal enterocytes

E V O'Loughlin, G P Pang, R Noltorp, C Koina, R Batey, and R Clancy

Gut 2001; 49: 636-643. doi:10.1136/gut.49.5.636

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Allelic variation at the interleukin 1 gene is associated with decreased bone mass in patients with inflammatory bowel diseases

A Nemetz, M Tóth, M A García-González, T Zágoni, J Fehér, A S Peña, and Z Tulassay

Gut 2001; 49: 644-649. doi:10.1136/gut.49.5.644

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Acute gastrointestinal permeability responses to different non-steroidal anti-inflammatory drugs

E Smecuol, J C Bai, E Sugai, H Vazquez, S Niveloni, S Pedreira, E Mauriño, and J Meddings

Gut 2001; 49: 650-655. doi:10.1136/gut.49.5.650

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Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide

P W Lowry, C L Franklin, A L Weaver, C L Szumlanski, D C Mays, E V Loftus, W J Tremaine, J J Lipsky, R M Weinshilboum, and W J Sandborn

Gut 2001; 49: 656-664. doi:10.1136/gut.49.5.656

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Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease

P W Lowry, C L Franklin, A L Weaver, M Gennett Pike, D C Mays, W J Tremaine, J J Lipsky, and W J Sandborn

Gut 2001; 49: 665-670. doi:10.1136/gut.49.5.665

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High level perinuclear antineutrophil cytoplasmic antibody (pANCA) in ulcerative colitis patients before colectomy predicts the development of chronic pouchitis after ileal pouch-anal anastomosis

P R Fleshner, E A Vasiliauskas, L Y Kam, N E Fleshner, J Gaiennie, M T Abreu-Martin, and S R Targan

Gut 2001; 49: 671-677. doi:10.1136/gut.49.5.671

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Pancreas and biliary tract:

Risk of pancreatic cancer after cholecystectomy: a cohort study in Sweden

W Ye, J Lagergren, O Nyrén, and A Ekbom

Gut 2001; 49: 678-681. doi:10.1136/gut.49.5.678

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Improving prognosis following a first variceal haemorrhage over four decades

P A McCormick and C O'Keefe

Gut 2001; 49: 682-685. doi:10.1136/gut.49.5.682

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Can endoscopic papillary balloon dilation really preserve sphincter of Oddi function?

I Yasuda, E Tomita, M Enya, T Kato, and H Moriwaki

Gut 2001; 49: 686-691. doi:10.1136/gut.49.5.686

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Motility and visceral sensation:

Inhibitory motor innervation of the gall bladder musculature by intrinsic neurones containing nitric oxide in the Australian Brush-tailed possum (Trichosurus vulpecula)

A C B Meedeniya, B O Al-Jiffry, H Konomi, A C Schloithe, J Toouli, and G T P Saccone

Gut 2001; 49: 692-698. doi:10.1136/gut.49.5.692

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Interaction of human chagasic IgG with human colon muscarinic acetylcholine receptor: molecular and functional evidence

L Sterin-Borda, J C Goin, C R Bilder, G Iantorno, A C Hernando, and E Borda

Gut 2001; 49: 699-705. doi:10.1136/gut.49.5.699

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Cardiac autonomic function and oesophageal acid sensitivity in patients with non-cardiac chest pain

G Tougas, R Spaziani, S Hollerbach, V Djuric, C Pang, A R M Upton, E L Fallen, and M V Kamath

Gut 2001; 49: 706-712. doi:10.1136/gut.49.5.706

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Liver disease:

Regulation of E-box DNA binding during in vivo and in vitro activation of rat and human hepatic stellate cells

K J Vincent, E Jones, M J P Arthur, D E Smart, J Trim, M C Wright, and D A Mann

Gut 2001; 49: 713-719. doi:10.1136/gut.49.5.713

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Extrahepatic portal vein thrombosis: aetiology and determinants of survival

H L A Janssen, A Wijnhoud, E B Haagsma, S H M van Uum, C M J van Nieuwkerk, R P Adang, R A F M Chamuleau, J van Hattum, F P Vleggaar, B E Hansen, F R Rosendaal, and B van Hoek

Gut 2001; 49: 720-724. doi:10.1136/gut.49.5.720

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Case reports:

Treatment of intestinal Behçet's syndrome with chimeric tumour necrosis factor antibody

S P L Travis, M Czajkowski, D P B McGovern, R G P Watson, and A L Bell

Gut 2001; 49: 725-728. doi:10.1136/gut.49.5.725

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Reviews:

The hepatorenal syndrome

L DAGHER and K MOORE

Gut 2001; 49: 729-737. doi:10.1136/gut.49.5.729

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Letters to the editor:

Coeliac disease and birth defects in offspring • Reply

K K HOZYASZ and L GRECO

Gut 2001; 49: 738. doi:10.1136/gut.49.5.738

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H pylori and functional dyspepsia • Reply

N J TALLEY and K E L McCOLL

Gut 2001; 49: 738-739. doi:10.1136/gut.49.5.738a

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The future of ERCP training in the UK • Reply

I A MURRAY, S PATHMAKANTHAN, R HEELEY, M T DONNELLY, M D HELLIER, and A I MORRIS

Gut 2001; 49: 739-740. doi:10.1136/gut.49.5.739

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Book reviews:

Evidence-Based Surgery

D ALDERSON

Gut 2001; 49: 740. doi:10.1136/gut.49.5.740

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Management of the Child with a Serious Infection or Severe Malnutrition. Guidelines for Care at the First-Referral Level in Developing Countries

C DOHERTY

Gut 2001; 49: 740. doi:10.1136/gut.49.5.740a

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Advanced Therapy of Inflammatory Bowel Disease

D RACHMILEWITZ

Gut 2001; 49: 740. doi:10.1136/gut.49.5.740b

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Liver Biopsy Interpretation

A KNISELY

Gut 2001; 49: 740. doi:10.1136/gut.49.5.740c

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Hirschsprung's Disease and Allied Disorders,

E R HOWARD

Gut 2001; 49: 740. doi:10.1136/gut.49.5.740d

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